I use AWS Certificate Manager primarily for managing SSL certificates. This includes issuing certificates for domains hosted in different environments and integrating them with Elastic Load Balancer and EC2 instances.
AWS Certificate Manager is a service that lets you easily provision, manage, and deploy public and private Secure Sockets Layer/Transport Layer Security (SSL/TLS) certificates for use with AWS services and your internal connected resources. SSL/TLS certificates are used to secure network communications and establish the identity of websites over the Internet as well as resources on private networks. AWS Certificate Manager removes the time-consuming manual process of purchasing, uploading, and renewing SSL/TLS certificates.