Microsoft Defender for Endpoint vs VirusTotal comparison

Microsoft Defender for Endp...

Read 11 VirusTotal reviews

5,217 Views
3,861 Comparison Views

100% willing to recommend

Comparison Buyer's Guide

Download the report

Executive SummaryUpdated on Jul 27, 2025

VirusTotal and Microsoft Defender for Endpoint compete in the cybersecurity space. Microsoft Defender for Endpoint appears to have the advantage due to its extensive security features and integrated threat management tools.

Features: VirusTotal offers multi-engine scanning for comprehensive threat analysis, efficient detection, and community-driven insights. Microsoft Defender for Endpoint provides advanced threat protection, real-time security monitoring, and automated response tools.

Room for Improvement: VirusTotal could enhance its integration capabilities, improve dark web scanning, and expand customer support. Microsoft Defender for Endpoint might improve user interface simplicity, enhance customer training resources, and further optimize system resource usage.

Ease of Deployment and Customer Service: VirusTotal is easy to deploy with a focus on straightforward file and URL analysis, yet offers limited customer service. Microsoft Defender for Endpoint involves a more complex setup but provides comprehensive support services as part of its deployment model.

Pricing and ROI: VirusTotal is cost-effective for quick threat assessments without a significant ROI impact. Microsoft Defender for Endpoint presents a higher initial cost but offers substantial ROI by reducing security risks and providing superior protection and management capabilities.

To learn more, read our detailed Microsoft Defender for Endpoint vs. VirusTotal Report (Updated: September 2025).

Microsoft Defender for Endpoint vs. VirusTotal

September 2025

Download the complete report

Helped 870,623 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Microsoft Defender for Endp...

Ranking in Anti-Malware Tools

1st

Average Rating

8.2

Reviews Sentiment

7.1

Number of Reviews

198

Ranking in other categories

Endpoint Protection Platform (EPP) (2nd), Advanced Threat Protection (ATP) (3rd), Endpoint Detection and Response (EDR) (3rd), Microsoft Security Suite (5th)

VirusTotal

Ranking in Anti-Malware Tools

3rd

Average Rating

8.8

Reviews Sentiment

7.3

Number of Reviews

Ranking in other categories

Threat Intelligence Platforms (TIP) (3rd)

Mindshare comparison

As of October 2025, in the Anti-Malware Tools category, the mindshare of Microsoft Defender for Endpoint is 13.7%, down from 19.1% compared to the previous year. The mindshare of VirusTotal is 4.4%, down from 5.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.

Anti-Malware Tools Market Share Distribution
Product	Market Share (%)
Microsoft Defender for Endpoint	13.7%
VirusTotal	4.4%
Other	81.9%

Anti-Malware Tools

Featured Reviews

NaySan @ Suraj Verma

Solution Consultant at BIM Group of Companies

Has effectively blocked sophisticated attacks and malicious activities while providing excellent support

Microsoft Defender for Endpoint is very good, but one suggestion is that in some products, we may need to configure security-related settings, whereas Microsoft Defender for Endpoint works completely differently, providing automatic recommendations and actions that we may need to perform ourselves. Regarding the pricing of Microsoft Defender for Endpoint, during the last three years, we set up the product and sold it, but we faced difficulties because Microsoft pricing is always the same. For example, whether I purchase Microsoft Defender for Endpoint for one year or for the next three years, the pricing remains constant with no discounts available. In contrast, competing products offer reduced pricing for long-term commitments, which makes it difficult for us in that environment. Microsoft should consider this option to remain competitive, but otherwise, everything else is fine.

Read full review

Chinmay Banerjee

Advisor Adtech/Martech/API product/project Engineering at Fiserv

Helps businesses collect threat data while keeping privacy in mind and apable of detecting, blocking, and removing viruses and malware

There are two gray areas I still need to explore. I have worked with VirusTotal because it easily integrates with over seventy antivirus scanners and blacklisting services. In addition to those there is much scope to improve and add other services or integrations. The areas for improvement are that VirusTotal is not using much AI or generative AI models, while other competitors are starting to build them. For example, VirusTotal's work is based on the setup done by their engineers. If you want to do scanning or protection activities for a specific site, app, or device, that is the area VirusTotal is currently focused on. But other competitors are building AI models that can do things like left-side scanning and provide auto-generated reports. VirusTotal has predefined reports, but there is a lot of manual effort involved. Secondly, the API is very limited if I want to integrate VirusTotal with other applications. They need to build more connectors and provide support for Webhook connectors for the API. If you can't build your own connector, it's always good to have provisions for Webhook setup connectors across platforms. Thirdly, Kaspersky, a competitor of VirusTotal, is using a methodology called "gatekeeper." A gatekeeper is a security system that protects the inside of a building from outside threats. This is the model Kaspersky is currently using. You have your website set up, but the entire army of VirusTotal or Kaspersky is standing guard, protecting you from the first gate itself. Right now, VirusTotal detects threats from your domain, but it is always better to verify inside the domain and protect it from the first level when people or malware are entering. This first level of protection is lacking in VirusTotal right now. The security bridge and protection gate are missing.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"DFE organizational security posture has been a positive experience. We're a Microsoft house. It works. Once it's deployed and once it's configured, it works and our clients tend to be happy with it. I haven't really experienced anyone who has been so unsatisfied with the platform that they wanted to go a couple of different directions, that has never happened to me."

"Ensures that I'm working with a product that gets updated regularly without me having to remember to do it. Since it's a Microsoft product, I'm confident that it requires a low use of system resources. The benefit of that being that my computer isn't constantly being drained."

"Defender for Endpoint is a robust solution that works well out-of-the-box."

"The main features of this solution are that it handles everything by itself and is well integrated."

"One of the best features of Microsoft Defender for Endpoint is called Threat and Vulnerability Management, TVM, which provides real-time visibility of vulnerabilities and misconfiguration at our endpoint level and helps prioritize and remediate based on risk information."

"I enjoy using the live response feature, which allows me to remotely access different endpoints and investigate malicious files, such as malware that people may have downloaded, and other related issues."

"It's an enterprise solution that provides a centralized console and it supports all the platforms that we use, including Windows, Linux, Mac, iOS, and Android."

"Microsoft Defender for Endpoint has helped reduce our mean time to remediation significantly."

More Microsoft Defender for Endpoint pros

"VirusTotal provides 95% to 98% accurate information."

"The feature I like the most is the ability to see the MD5 or SHA-256 signature of the file, and also the composition of the file according to its segments."

"It gives detailed information about suspicious IPs, which is one of its most valuable features."

"It can scan the dark web and find if an email ID has been compromised. This is another area that we have not explored yet."

"VirusTotal provides 95% to 98% accurate information."

"It is quite simple for anyone if they just want to check some suspicious URLs."

"It allows us to see if there have been previous reports on certain indicators of compromise, providing insights from other security professionals."

"The initial setup is easy."

More VirusTotal pros

Cons

"The solution should be updated by Microsoft with new features from time to time."

"The solution could be more friendly for end-users, with different type of scans or scheduled scans for it."

"The integration and effectiveness of email security could be better. It's already built-in to the solution and checks emails, scans the links they contain etc."

"Microsoft Defender for Endpoint could provide us with a more holistic approach, such as collaboration. They can provide us with an environment from where we can manage all the endpoints from one central location, such as overall management."

"The solution can be more user-friendly."

"Localization is always a challenge, especially with new products you typically want. Solutions are designed to be deployed where the most licenses are being consumed, such as in the United States. They focus on US products, devices, and networks. Specialized deployments for other countries would allow for a smoother experience in transition."

"The user interface could use some improvement."

"I would like Microsoft to have some kind of direct integration for USB controls. They have GPO and other controls to control the access of the USB drives on devices, but if there is something that can be directly implemented into the portal, it would be good. There should be a way to control via a cloud portal or something like that in a dynamic way. USB control for data exfiltration would be a good feature to implement. Currently, there are ways to do it, but it involves too many different things. You have to implement it via GPOs and other stuff, and then you move or copy those big files via Defender ATP. If there is a simple way of implementing those features, it would be great."

More Microsoft Defender for Endpoint cons

"They can improve the telemetry. Whenever we handle a sample, they cannot provide any information about a victim."

"There should be room for improvement, particularly in the API side of things."

"VirusTotal needs better advertisement and promotion, especially in the Middle East, since it is not yet widely recognized or popular in that region."

"I would like to see an improved user interface and some automation."

"VirusTotal is hard to understand because you need to know Google Docs to create queries, and it doesn't have documentation for that."

"I would like to see improved correlation with other threat intelligence sources, not just reliant on its own database, to enhance the database of threat intelligence that VirusTotal offers."

"There is room for improvement, particularly in making some of the most useful features more accessible in the non-paid version."

"VirusTotal has different versions, and sometimes the parameters of the API are not very clear."

More VirusTotal cons

Pricing and Cost Advice

"Currently, for us, Windows Defender is free with the purchase of Windows Server. Pricing is an important point for us when we are looking at the competitors of this solution. If we choose to go with another vendor, we will have to pay some license fees."

"We have the E5 security license, and the solution comes with that."

"If you don't purchase the advanced threat protection then there is no additional charge."

"Microsoft Defender for Endpoint is more affordable compared to some other endpoint solutions."

"The normal, standalone model, is not expensive, but the enterprise model that includes the bundle with email and some web protection, is a bit more expensive."

"The nice thing about Defender and Sentinel is that the cost is based on the data logs that you ingest from the Defender endpoints and data connectors. I don't have to buy a 25- or 50- or 1,000-user or enterprise license. I can buy one license at a time."

"You don't need to worry about the renewal and purchase of antivirus products. It is bundled with Windows 10, so you don't need to worry about separately purchasing any antiviruses."

"There is an annual license required."

More Microsoft Defender for Endpoint pricing and cost advice

"VirusTotal is an expensive solution."

"The pricing is reasonable."

"We are using VirusTotal with free licenses, managing the license limits across three or four accounts, thus incurring no costs."

"The pricing is very economical."

See which vendors are best for you

Use our free recommendation engine to learn which Anti-Malware Tools solutions are best for your needs.

See recommendations

870,623 professionals have used our research since 2012.

Top Industries

By visitors reading reviews

Computer Software Company

13%

Manufacturing Company

Financial Services Firm

Government

Computer Software Company

19%

Financial Services Firm

University

Government

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

By reviewers
Company Size	Count
Small Business	79
Midsize Enterprise	34
Large Enterprise	87

By reviewers
Company Size	Count
Small Business	4
Midsize Enterprise	2
Large Enterprise	5

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?

Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...

Which offers better endpoint security - Symantec or Microsoft Defender?

We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...

How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?

The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...

What do you like most about VirusTotal?

With VirusTotal, I can check for any hash, malware, file, domain, IP URL, or malicious URL, and Kaspersky stays clean.

What is your experience regarding pricing and costs for VirusTotal?

I do not know about the pricing or licensing as our organization services VirusTotal for our clients.

What needs improvement with VirusTotal?

I would like to see improvements in the score consistency and accuracy. VirusTotal should add more details like those from competitors such as URL Void or Symantec URL Checker, which show the categ...

HP Wolf Security vs Microsoft Defender for Endpoint

Comparisons

Compared 5% of the time

CrowdStrike Falcon vs Microsoft Defender for Endpoint

Compared 5% of the time

F-Secure Total vs Microsoft Defender for Endpoint

Compared 4% of the time

Symantec Endpoint Security vs Microsoft Defender for Endpoint

Compared 4% of the time

Trellix Endpoint Security Platform vs Microsoft Defender for Endpoint

Compared 4% of the time

More Microsoft Defender for Endpoint Competitors

MetaDefender vs VirusTotal

Compared 14% of the time

ANY.RUN vs VirusTotal

Compared 11% of the time

Recorded Future vs VirusTotal

Compared 9% of the time

Cuckoo Sandbox vs VirusTotal

Compared 8% of the time

ReversingLabs vs VirusTotal

Compared 5% of the time

More VirusTotal Competitors

Product Reports

Microsoft Defender for Endpoint

September 2025

Download Microsoft Defender for Endpoint product report

Download VirusTotal product report

Anti-Malware Tools

January 2025

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus

No data available

Interactive Demo

Microsoft

Demo not available

Overview

Microsoft Defender for Endpoint is a comprehensive security solution that provides advanced threat protection for organizations. It offers real-time protection against various types of cyber threats, including malware, viruses, ransomware, and phishing attacks.

With its powerful machine-learning capabilities, it can detect and block sophisticated attacks before they can cause any harm. The solution also includes endpoint detection and response (EDR) capabilities, allowing organizations to quickly investigate and respond to security incidents. It provides detailed insights into the attack timeline, enabling security teams to understand the scope and impact of an incident.

Microsoft Defender for Endpoint also offers proactive threat hunting, allowing organizations to proactively search for and identify potential threats within their network. It integrates seamlessly with other Microsoft security solutions, such as Microsoft Defender XDR, to provide a unified and holistic security approach. With its centralized management console, organizations can easily deploy, configure, and monitor the security solution across their entire network.

Microsoft Defender for Endpoint is a robust and scalable security solution that helps organizations protect their endpoints and data from evolving cyber threats.

Microsoft

VirusTotal provides a comprehensive digital security platform by leveraging a vast malware database. It integrates numerous antivirus scanners for robust malware and virus detection, offering valuable insights for threat intelligence and security analysis.

VirusTotal is widely used for malware analysis and cybersecurity investigations, relying on its extensive capabilities in file and IP analysis. It integrates seamlessly with various antivirus engines, ensuring detailed threat intelligence. The platform excels at performing automated reputation checks, gleaning insights from a robust community, and delivering comprehensive information on suspicious activities. With an API system, it facilitates deeper analysis and integration into existing security workflows.

What are the standout features of VirusTotal?

Vast Malware Database: A comprehensive repository for malware intelligence.
Integration with Antivirus Scanners: Collaborates with multiple scanners for enhanced detection.
File and IP Analysis: Detailed insights into files and IP addresses.
Automated Reputation Checks: Efficiently verifies file and domain safety.
Community Insights: Gathers valuable data from an active community.

What benefits and ROI should be considered?

Threat Intelligence: Informs strategic security decisions with detailed malware data.
Enhanced Detection: Supports comprehensive threat identification and response.
Contextual Analysis: Provides extensive details for thorough investigation of threats.

In sectors like retail, FinTech, and GRC, VirusTotal is integrated into cybersecurity workflows to enhance incident response capabilities. It is invaluable for analyzing phishing websites, inspecting URLs, identifying compromised information, and generating alerts for specific threats. APIs enable deeper examination of suspicious activity, supporting comprehensive cybersecurity operations.

Sample Customers

Petrofrac, Metro CSG, Christus Health

Information Not Available