Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

Cisco and Nutanix are both solutions in the HCI category. Additionally, 89% of Cisco users are willing to recommend the solution, compared to 94% of Nutanix users who would recommend it.

Cisco HyperFlex HX-Series [...

Read 90 Cisco HyperFlex HX-Series [EOL] reviews

89% willing to recommend

Nutanix Cloud Infrastructur...

Read 197 Nutanix Cloud Infrastructure (NCI) reviews

12,656 Views
5,694 Comparison Views

94% willing to recommend

Cisco HyperFlex HX-Series [...

Nutanix Cloud Infrastructur...

Comparison Buyer's Guide

Download the report

Executive SummaryUpdated on Jan 12, 2025

Nutanix Cloud Infrastructure (NCI) and Cisco HyperFlex HX-Series [EOL] compete in the cloud infrastructure category. Nutanix Cloud Infrastructure seems to have the upper hand with its robust features, though both have areas for improvement and various deployment and ROI models.

Features: Nutanix Cloud Infrastructure features high availability, ease of administration, and seamless scalability. Its hyper-converged infrastructure provides data protection and storage auto-tiering. One-click upgrades optimize performance. Cisco HyperFlex HX-Series, while integrated well with Cisco ecosystems, lacks software-defined capabilities and data locality features.

Room for Improvement: NCI could improve network integration and hypervisor support, and offer better pricing transparency. Enhanced connectivity with older systems is also needed. Cisco HyperFlex faced scalability issues and challenges with third-party cloud integration, suggesting room for better documentation and license management.

Ease of Deployment and Customer Service: Nutanix Cloud Infrastructure offers flexible deployment for on-premises, hybrid, and private cloud environments, with outstanding customer service. In contrast, Cisco HyperFlex struggled with deployment complexities in multi-site integrations, though it offers reliable customer service but requires more technical expertise.

Pricing and ROI: Nutanix Cloud Infrastructure is seen as more cost-effective over time, despite a high initial cost, due to reduced operational expenses and a free hypervisor. Cisco HyperFlex, although initially attractively priced, incurs higher long-term costs due to additional licensing, making Nutanix a more favorable option for sustained savings.

To learn more, read our detailed HCI Report (Updated: March 2025).

Buyer's Guide

HCI

March 2025

Download the complete report

Helped 842,767 peers since 2012

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Cisco HyperFlex HX-Series [...

Average Rating

8.0

Reviews Sentiment

6.7

Number of Reviews

Ranking in other categories

No ranking in other categories

Nutanix Cloud Infrastructur...

Average Rating

8.6

Reviews Sentiment

7.4

Number of Reviews

197

Ranking in other categories

Software Defined Storage (SDS) (3rd), HCI (3rd), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (5th)

Featured Reviews

Nuno Mendes

IT Manager - Resp.Department at Parvalorem

High performance solution that makes it easy to efficiently manage VM resources

In our case as a credit recovery company working with the state, our infrastructure is fixed and stable as we don't have the same need for growth as other types of companies. That said, one of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application. Since we as a company will only be operating for perhaps the next ten years, when our HyperFlex solution comes to its end-of-life in 2024 our next step will likely not be with HyperFlex or any other solution from Cisco. Instead, from a financial point of view, we will likely turn toward a cloud solution because, that way, we won't have to spend so much money on physical infrastructure. We are, after all, only a small company and HyperFlex can be very expensive for other companies of our size, whether in Portugal or elsewhere like the United States. One other area for improvement is in regard to HyperFlex's integration with VMware. HyperFlex integrates with a specific version of VMware in such a way that HyperFlex doesn't always resolve security issues with VMware at the same pace as what you see in native implementations of VMware. This has happened in one or two situations in the past. On the other hand, the integration is otherwise adequate, especially in terms of availability and virtualization features (such as being able to split up each of our four hosts within VMware).

Read full review

MahendraPanchotiya

Infrastructure Manager at ER Tech Pros

Offers a unified platform, reduces downtime, and simple updates

Nutanix offers a unified platform for managing databases, virtual machines, and applications. This simplifies management by consolidating everything into a single interface. While Nutanix may have a higher upfront cost compared to other hypervisors, it can significantly reduce the resources needed for infrastructure management. With our previous hypervisor, we needed nearly ten IT personnel. Nutanix has allowed us to streamline our team to just three members. We use a combination of database technologies, including SQL databases and web servers such as IIS, BHP, and NGINX. Nutanix features helped our organization reduce downtime. I don't recall the last time we had downtime related to Nutanix because it is such a stable product. Nutanix, a reliable product, helps us streamline our processes, which in turn improves company revenue. We began to see the benefits after two years, with a 40 percent reduction in operational costs. We migrated 200 servers from AWS to Nutanix. Nutanix may not consolidate applications, but it helps us run them more efficiently on its platform. Updating is simple with one click. I would rate the updating processes 10 out of 10. Adding compute and storage on demand is not difficult. However, we need to factor in the existing and new firmware and software requirements.

Read full review

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"On the VDI side, because the storage is local to the HyperFlex, it was very easy and convenient. The performance is exceptional."

"Our customers have seen ROI in terms of the time they save troubleshooting."

"It increases efficiency, decreases the cost, and manages the network in one single way. That's the most important thing."

"It saves space for data centers, which is good."

"Most of our users are Cisco customers, so it fits in within the suites we use. Primarily for me, as a solution architect, it's the technology and architecture that is the most valuable. I know from my technical colleagues that it's easy to use and for the customer, the up-time is the most valuable asset. It's running, has low failure, and so on which is why we use it."

"It allows us to authorize our residents to come in using their own personal devices to access any of our clinical applications and ensure that the PHI is secure and protected."

"The most valuable features are scalability and the easy operation - if it works. You can configure everything from just one window."

"The most valuable features of this solution are scalability, performance, and reliability. It scales well inside of a large data center."

More Cisco HyperFlex HX-Series [EOL] pros

"It supports multi-cloud integration that includes AWS, Google, and Azure."

"One-Click Upgrade and Foundation is the most valuable feature. One-Click Upgrade makes upgrades and LCM a breeze. Prior to Nutanix One-Click Upgrade, upgrades and LCM were overly cumbersome and time-consuming. Foundation provides an easy, yet very structured, approach to cluster modification (adding or removing nodes)."

"The most valuable features are the RBAC, role-based access control, and the reporting. NCI also provides a single platform, a single pane with a dashboard, to manage the entire infrastructure. We have complete information about overall utilization, performance, and a forecast for our platform in that single pane."

"One of the main features of the solution is that it works on many hypervisors. It is a big advantage. Additionally, the solution is compatible with VMware and Hyper-V, and the management interface, which is called Prism, is very intuitive and user-friendly."

"Some of the most valuable features of Nutanix Acropolis are that it's free from Nutanix and it's very stable."

"It gives us a single dashboard to control multiple sites and multiple zones. It helps to do things on a single platform and data sharing is quite easy. The network and the security are easy to manage."

"The maintenance software is straightforward because you do not need to do any configuration."

"Data locality provides super-fast data access and ultra-low latency."

More Nutanix Cloud Infrastructure (NCI) pros

Cons

"Technical support is very good. Not excellent, but good. There's still not enough data available on the web. For example, for the integration to VMware, I had a case recently and I searched for more information but didn't find any."

"The product does not have a cloud version...The product should be made more flexible in terms of integration capabilities."

"There should be the opportunity to create more than one div group"

"One of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application."

"We'd like the product to offer better integration with other products."

"We would like to move off the GUI."

"The initial setup can be a bit complex."

"You have to get the same servers with the same storage; they need to be identical. However, in vSAN or in VMware we don't have to do that. We can just add storage and manage it in the same server."

More Cisco HyperFlex HX-Series [EOL] cons

"To have internal stability, we needed to network the solution ourselves. Performance depends on the application. Performance could be the lack of IOPS, memory and CPU and configuration issues."

"There should be a little more access to Nutanix files."

"The initial setup can be a bit difficult."

"The process of migrating from old hardware to new could improve."

"They have offered some new features that I have not deployed so I assume that these issues might have been addressed already, but, at my time there was a networking problem."

"The only problem is that not many operating systems are supported on the AOS hypervisor. They need to probably increase the support on multiple operating systems. As of now, a very limited number of operating systems and patch levels are supported on AOS."

"Storage utilization and optimization should be better."

"USB dongle-based licenses do not allow us to directly locate the USB ports on Nutanix."

More Nutanix Cloud Infrastructure (NCI) cons

Pricing and Cost Advice

"Comparable solutions with switches, storage, and services are cheaper than HyperFlex. It should be cheaper."

"Its price is rather fair when compared with other solutions like VxRail, vSAN, and HPE SimpliVity. We got a fair amount of discount from Cisco for Cisco HyperFlex. It is cost-effective. We have renewed storage till next year, and we have already paid the vendor. When we talk about HyperFlex or any HCI solution, storage is the part where we can reduce a lot of costs. At the current moment, we are already using NetApp storage, which did not allow us to go for a full Cisco HyperFlex setup. We are planning to go to a larger scale next year. Then we will be able to see how cost-effective it really is for us."

"It's roughly $30,000 per Hyperflex license, so that would be about $60,000 a year."

"Our licensing costs are large, but it is combined between all of the Cisco products that we have."

"It is highly priced compared to other vendors."

"The cost is expensive, but there is a chance to save money in the future."

"The licensing is perpetual and the only thing that you may need to pay for on a monthly basis is if you're going to use their cloud-based management features."

"There is a license required to use this solution."

More Cisco HyperFlex HX-Series [EOL] pricing and cost advice

"The product’s licensing fee is moderately expensive."

"Nutanix Cloud Infrastructure is expensive."

"In terms of the solution's licensing, it's quite comprehensive."

"They should lower the price. If they did they would fall into a more competitive market because the price does scare a lot of potential customers away when they get the quote."

"Its price is fine. I can't really complain about that."

"The price is good but I think there is still room for improvement on the price."

"We renew our license on a yearly basis and have no costs in addition to the standard fee."

"Its licensing model is easy, but the bad thing is that we need to pay for the whole capacity at once. With VMware vSAN, we only have to pay for the capacity that we are using, which is not the case with Nutanix. So, we have more overhead for the licensing cost with Nutanix."

More Nutanix Cloud Infrastructure (NCI) pricing and cost advice

See which vendors are best for you

Use our free recommendation engine to learn which HCI solutions are best for your needs.

See recommendations

842,767 professionals have used our research since 2012.

Comparison Review

it_user244362

Managing Consultant with 51-200 employees

Aug 30, 2015

Nutanix vs. VMware EVO:RAIL vs. FlexPod

Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…

Read full review

Answers from the Community

Netanya Carmi

Content Manager at PeerSpot

Aug 2, 2022

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

See 2 answers

Leah Fainchtein Buenavida

Tech Blogger

Oct 17, 2021

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.

Read full answer

Steffen Hornung

Administrator at Neuberger Gebäudeautomation GmbH

Aug 2, 2022

With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.

Read full answer

Top Industries

By visitors reading reviews

Computer Software Company

27%

Financial Services Firm

Government

Manufacturing Company

Educational Organization

36%

Computer Software Company

12%

Financial Services Firm

Manufacturing Company

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...

See all answers

How does VxRail compare with Cisco HyperFlex HX Series?

VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...

See all answers

What do you like most about Cisco HyperFlex HX-Series?

It's easy to get the tool started.

See all answers

What is the biggest difference between Nutanix Acropolis and VMware vSphere?

We found the reduced power consumption with Nutanix Acropolis AOS a very attractive feature. We also like the interface that allows you to talk directly to your VM from the present software. We fou...

See all answers

Which would you choose - Nutanix Acropolis AOS or VMware vSAN?

See all answers

What makes Nutanix Cloud Infrastructure (NCI) worth using?

NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...

See all answers

Comparisons

VMware vSAN vs Cisco HyperFlex HX-Series [EOL]

Compared 30% of the time

VxRail vs Cisco HyperFlex HX-Series [EOL]

Compared 24% of the time

HPE SimpliVity vs Cisco HyperFlex HX-Series [EOL]

Compared 19% of the time

Dell PowerFlex vs Cisco HyperFlex HX-Series [EOL]

Compared 10% of the time

More Cisco HyperFlex HX-Series [EOL] Competitors

VxRail vs Nutanix Cloud Infrastructure (NCI)

Compared 8% of the time

VMware vSphere vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Dell PowerFlex vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

HPE SimpliVity vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Hyper-V vs Nutanix Cloud Infrastructure (NCI)

Compared 5% of the time

More Nutanix Cloud Infrastructure (NCI) Competitors

Product Reports

Buyer's Guide

Cisco HyperFlex HX-Series [EOL]

March 2025

Download Cisco HyperFlex HX-Series [EOL] product report

Buyer's Guide

Nutanix Cloud Infrastructure (NCI)

March 2025

Nutanix Cloud Infrastructure (NCI) report

Download Nutanix Cloud Infrastructure (NCI) product report

Also Known As

No data available

Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis

Overview

The Cisco HyperFlex HX Data Platform is a purpose-built, high-performance, scale-out file system with a wide array of enterprise-class data management services. The data platform’s innovations redefine distributed storage technology, giving you complete hyper-convergence with enterprise storage features:

Enterprise-class data management
Continuous data optimization
Securely encrypted storage
Dynamic data placement
Clusterwide parallel data distribution
Linear and incremental scaling
API-based data platform architecture
A simplified approach

Cisco

Nutanix Cloud Infrastructure (NCI) is a top-ranking HCI software, cloud management tool, and Software Defined Storage (SDS) tool that is marketed as the foundation for users' hybrid clouds. It offers a powerful and secure hyperconverged infrastructure to deliver all data and applications at any scale and on any cloud. The solution offers a complete software stack that allows users to unify their hybrid cloud infrastructure.

NCI’s services include computer, storage and network, hypervisors and containers, and deployment in public or in private clouds. The product also comes with built-in resilience, disaster recovery capabilities, self-healing, and high-security capacities. It provides further deployment flexibility through several software and hardware options and platforms. NCI includes a full set of enterprise capabilities. It can also be deployed on a wide range of servers from popular manufacturers.

The capabilities of the product are categorized into three main groups:

AOS storage
Flexible and open compute
Automated and secure networking

Outside of these categories, NCI also offers other capabilities:

Integrated disaster recovery
Full-stack lifecycle management
VMware with Nutanix
Intelligent operations

Nutanix Cloud Infrastructure (NCI) Features

Nutanix Cloud Infrastructure (NCI) offers its customers various features and tools in each of the previously mentioned categories. The available features for users currently include:

High-performance: This set of features utilizes hardware advances such as NVMe and RDMA to accelerate users' most demanding applications with consistent performance. The tools in this feature category work alongside data locality to ensure successful results.
Foolproof resiliency: These Nutanix Cloud Infrastructure features protect data and keep it available by facilitating advanced distributed consistency algorithms. Users can utilize these features to protect their data from issues like bit rot, hardware failures, and even entire site failure.
Flexibility: This set of features allows storage to be sized for the needs of each organization and expanded promptly and easily so that the organization and its data can grow. The features offer flexibility to users in terms of applying storage policies logically on a pre-workload basis, instead of being tied to hardware.
Hypervisor choice: Users can choose from the leading hypervisors - Microsoft Hyper-V or VMware ESXi. They can also leverage the built-in hypervisor AHV that Nutanix Cloud Infrastructure (NCI) provides.
Integrated virtualization: These features offer simplified automation and AHV streamlined operations. The services in this category are optimized for high performance and reliability.
Kubernetes: Nutanix Cloud Infrastructure (NCI) offers features to build and deploy cloud-native applications on intelligent distributed infrastructure. Apps can be integrated with cloud-compatible storage and both building and deployment can be achieved within the same platform.
Microsegmentation: Nutanix Cloud Infrastructure (NCI) offers features to prevent malware spread and reduce attack surfaces by leveraging machine learning (ML).
Virtual networking: This set of features allows users to easily implement multi-tenancy in their environment or stretch networks across clouds.
Centralized network management: Nutanix Cloud Infrastructure (NCI) provides organizations with a way to manage networking configurations centrally. Users can utilize it across their human-computer interaction (HCI) environment with simple virtual switch management.

Nutanix Cloud Infrastructure (NCI) Benefits

The product offers various benefits to users who utilize its capacities. Some of these include:

NCI reduces technology sprawl and frees up technical resources to allow organizations to focus on other activities, potentially reducing costs for the business.
The product allows customers to deploy, scale, and bridge to the public cloud to be able to react in evolving business environments.
Nutanix Cloud Infrastructure improves data availability while simultaneously protecting it against several kinds of failures and attacks.
The solution offers high-performance, resilient distributed storage for all workloads.
Working alongside Nutanix Cloud Platform, NCI offers simple management of data from one console.
Nutanix Cloud Infrastructure works by the zero trust philosophy, protecting users' apps and data through specially designed security protocols.

Reviews from Real Users

According to Gerhard J., an IT manager at Q4 Fuel, Nutanix Cloud Infrastructure (NCI) provides serious reliability and stability across the entire system makes for ROI.

A solutions architect at a computer software company describes NCI as a stable, straightforward to set up, and scalable solution.

Nutanix

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest

St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.

Find out what your peers are saying about Dell Technologies, VMware, Nutanix and others in HCI. Updated: March 2025.

DOWNLOAD NOW

842,767 professionals have used our research since 2012.

See our list of best HCI vendors.

We monitor all HCI reviews to prevent fraudulent reviews and keep review quality high. We do not post reviews by company employees or direct competitors. We validate each review for authenticity via cross-reference with LinkedIn, and personal follow-up with the reviewer when necessary.