Cisco HyperFlex HX-Series [EOL] vs Nutanix Cloud Infrastructure (NCI) comparison

Cisco and Nutanix are both solutions in the HCI category. Additionally, 89% of Cisco users are willing to recommend the solution, compared to 94% of Nutanix users who would recommend it.

Cisco HyperFlex HX-Series [...

Read 90 Cisco HyperFlex HX-Series [EOL] reviews

89% willing to recommend

Nutanix Cloud Infrastructur...

Read 197 Nutanix Cloud Infrastructure (NCI) reviews

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5,694 Comparison Views

94% willing to recommend

Cisco HyperFlex HX-Series [...

Nutanix Cloud Infrastructur...

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Executive SummaryUpdated on Apr 20, 2025

Nutanix Cloud Infrastructure and Cisco HyperFlex HX-Series compete in the hyper-converged infrastructure market. NCI appears to have an advantage due to its robust feature set, ease of deployment, and customer service.

Features: Nutanix Cloud Infrastructure offers high performance I/O and high availability. It features ease of administration and advanced data management with distributed file systems supporting deduplication and compression. Cisco HyperFlex HX-Series, while integrating computing, storage, and networking, focused on scalability and Cisco environment integration but lacked some advanced functionality found in competitors.

Room for Improvement: Nutanix Cloud Infrastructure could enhance network integration, improve support for various hypervisors, and expand storage capabilities. Cisco HyperFlex faced challenges with cloud integration, scalability, and high cost, along with complex storage and backup integration issues.

Ease of Deployment and Customer Service: Nutanix Cloud Infrastructure is praised for easy deployment across on-premises and hybrid environments. It provides exceptional customer service with responsive support. Cisco HyperFlex, though providing good integration within Cisco ecosystems, can be complex and costly to deploy, and its support has received mixed reviews.

Pricing and ROI: Nutanix Cloud Infrastructure offers competitive pricing, with high performance and reduced downtime justifying the investment. Cisco HyperFlex is perceived as expensive, with high initial costs and licensing issues. Although some users report decent ROI, it varies significantly based on deployment scale and additional service costs.

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Buyer's Guide

HCI

March 2025

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Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Categories and Ranking

Cisco HyperFlex HX-Series [...

Average Rating

8.0

Reviews Sentiment

6.7

Number of Reviews

Ranking in other categories

No ranking in other categories

Nutanix Cloud Infrastructur...

Average Rating

8.6

Reviews Sentiment

7.4

Number of Reviews

197

Ranking in other categories

Software Defined Storage (SDS) (3rd), HCI (3rd), Software Defined Data Center (SDDC) (1st), Hybrid Cloud Computing Platforms (5th)

Featured Reviews

Nuno Mendes

IT Manager - Resp.Department at Parvalorem

High performance solution that makes it easy to efficiently manage VM resources

In our case as a credit recovery company working with the state, our infrastructure is fixed and stable as we don't have the same need for growth as other types of companies. That said, one of the biggest problems with HyperFlex HX is that if you want to adjust your solution in terms of processing power, memory, or disk capacity, you have to buy completely new hosts. From a financial perspective, it can be very expensive to do so, and from a legal perspective, there are all kinds of compliance issues we would have to sort out before buying any new solution or application. Since we as a company will only be operating for perhaps the next ten years, when our HyperFlex solution comes to its end-of-life in 2024 our next step will likely not be with HyperFlex or any other solution from Cisco. Instead, from a financial point of view, we will likely turn toward a cloud solution because, that way, we won't have to spend so much money on physical infrastructure. We are, after all, only a small company and HyperFlex can be very expensive for other companies of our size, whether in Portugal or elsewhere like the United States. One other area for improvement is in regard to HyperFlex's integration with VMware. HyperFlex integrates with a specific version of VMware in such a way that HyperFlex doesn't always resolve security issues with VMware at the same pace as what you see in native implementations of VMware. This has happened in one or two situations in the past. On the other hand, the integration is otherwise adequate, especially in terms of availability and virtualization features (such as being able to split up each of our four hosts within VMware).

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MahendraPanchotiya

Infrastructure Manager at ER Tech Pros

Offers a unified platform, reduces downtime, and simple updates

Nutanix offers a unified platform for managing databases, virtual machines, and applications. This simplifies management by consolidating everything into a single interface. While Nutanix may have a higher upfront cost compared to other hypervisors, it can significantly reduce the resources needed for infrastructure management. With our previous hypervisor, we needed nearly ten IT personnel. Nutanix has allowed us to streamline our team to just three members. We use a combination of database technologies, including SQL databases and web servers such as IIS, BHP, and NGINX. Nutanix features helped our organization reduce downtime. I don't recall the last time we had downtime related to Nutanix because it is such a stable product. Nutanix, a reliable product, helps us streamline our processes, which in turn improves company revenue. We began to see the benefits after two years, with a 40 percent reduction in operational costs. We migrated 200 servers from AWS to Nutanix. Nutanix may not consolidate applications, but it helps us run them more efficiently on its platform. Updating is simple with one click. I would rate the updating processes 10 out of 10. Adding compute and storage on demand is not difficult. However, we need to factor in the existing and new firmware and software requirements.

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Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:

Pros

"The most valuable feature of Cisco HyperFlex HX-Series is the integration with everything in a much smoother, such as in physical and virtual environments. VMware NSX is a simpler solution but, Cisco HyperFlex HX-Series is more robust compared to VMware NSX."

"The solution is stable."

"The speed, storage, and management are the most valuable features."

"I like Cisco Intersight."

"The most valuable feature of Cisco HyperFlex HX-Series is its performance."

"The integration between the storage and the server applications is the most valuable feature of this solution. It cuts down on the necessity to buy a secondary storage system.. It saves money in the long-run."

"It saves space for data centers, which is good."

"We are providing this solution for the customer or converting the customer from a traditional environment to a hyper-converged environment which consolidates all management and support on a single port. This is the main benefit of using the hyper-converged versus the traditional."

More Cisco HyperFlex HX-Series [EOL] pros

"Nutanix Acropolis AOS is flexible and has helped people to work from home during the pandemic."

"In general, being able to patch and not having to pay for SanDisk is the best thing about hyper-converged."

"The most valuable features are easy cloud administration and management."

"The level of statistical performance data that it can confirm in real-time is extremely useful. I can see what my VM’s hosts and guests are doing from a single pane of glass and identify issues before they would otherwise become apparent."

"You can be sure that whatever you patch is already compatible with the current firmware and the current version of the Acropolis that you're using."

"Acropolis AOS's networking concept is excellent."

"You need to send commands through the command-line interface(CLI). This could be improved. The commands are done better in VMware."

"Their Google operating system is more mature, so their results are much better."

More Nutanix Cloud Infrastructure (NCI) pros

Cons

"One aspect that really needs to be looked at, is to fix the bugs issue."

"Does not support the stretch cluster, and the interface is not good."

"The primary improvements should be made in the cluster storage controller VMs so that they don't break the upgrade process."

"We'd like the product to offer better integration with other products."

"The deployment could be made a little bit easier, as we still seem to struggle with it a little bit for a day or so to get it running."

"In the next release, Cisco should add more integration and management capabilities as well as some tweaks to the dashboard that make it more user-friendly. They could also add support for multiple hypervisors."

"They should give us a little more information about how to use the CLI and offer more commands."

"Cisco HyperFlex should decrease the amount of memory needed from the Controller VM that controls the physical discs. They control the discs by using the virtual VM over every ESXi host and the VM consumes memory and consumes more hardware resources. They have to improve that by decreasing the amount of required memory and CPUs to control this disc on the server."

More Cisco HyperFlex HX-Series [EOL] cons

"The reporting feature isn't very good."

"The GUI of Nutanix Acropolis AOS could be improved that can be done from the OEM side. It's a very basic stable web browser that they're using. It is not very inclusive."

"Deployment could be more user-friendly - currently, it requires certain skills with the network and nodes."

"The solution doesn't support older systems, which can be a problem for some organizations who wish to implement it. It became a problem for us due to the fact that some of our systems are older."

"The documentation could be improved."

"It already has the capability to integrate with the major cloud providers but, in an upcoming release, if there is a possibility to have it integrate with other cloud providers like IBM, Alibaba, and other moderate-level cloud providers, that would be good."

"The storage and back-up facilities could be improved. We need day-to-day encrypting of the database."

"Nutanix Cloud Infrastructure lacks compatibility with certain older processors."

More Nutanix Cloud Infrastructure (NCI) cons

Pricing and Cost Advice

"It is relatively expensive, but it can easily return value by freeing up other resources."

"We would not have invested if we didn't feel the return was there for our customers."

"We currently have a perpetual license, which is kind of unlimited, so we don't have the normal licensing cost, yet."

"Pricing is better if you buy more Cisco products."

"Cisco HyperFlex HX-Series is a bit pricier compared to other brands in the market...There is a need to make additional payments towards the maintenance and support of the solution."

"HyperFlex is relatively expensive, but you get good value for money."

"Cisco HyperFlex HX-Series is expensive. It's a standard license, and we pay for it yearly. I think we pay about 700."

"HyperFlex is a little pricey."

More Cisco HyperFlex HX-Series [EOL] pricing and cost advice

"Many of my customers have issues with Acropolis' licensing model because they are charging the customers based on two things— the CPUs and the capacity in the solid stack disk — and that's a problem. Nutanix's competitors are not licensing that layer, so this is something that they should change. They should abandon this licensing model because it's too complex. Technical support is bundled with the subscription."

"The initial cost is affordable but the renewal fees are high."

"The one disadvantage is relative, financially Nutanix Acropolis AOS is a little bit more expensive than the old solution."

"Work close with your InfraTeam and discuss with Nutanix the best way to achieve sizing and price that are right for you."

"If a customer has been using VMware, the difference in pricing is lower. However, if they are looking to use the VMware, the price can be much higher depending on the license."

"The price of the license for Nutanix Acropolis AOS is less expensive than the competition. There is a favorable cost saving. Having only the need to deal with a single vendor, the management of the customer's entire stack is cost-effective."

"My advice is to get the ultimate license, as it is worth it."

"Its licensing is fine. They provide the flexibility to choose from different options. You can go with the standard plan. You can go with the pro or platinum plan. Generally, our clients go with the pro licenses, but if you go for the platinum license, you get even more capabilities. Their starter license is also quite good."

More Nutanix Cloud Infrastructure (NCI) pricing and cost advice

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Comparison Review

it_user244362

Managing Consultant with 51-200 employees

Aug 30, 2015

Nutanix vs. VMware EVO:RAIL vs. FlexPod

Originally posted at www.storagegaga.com/dont-get-too-drunk-on-hyper-converged/ I hate the fact that I am bursting the big bubble brewing about Hyper Convergence (HC). I urge all to look past the hot air and hype frenzy that are going on, because in the end, the HC platforms have to be aligned…

Read full review

Answers from the Community

Netanya Carmi

Content Manager at PeerSpot

Aug 2, 2022

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

See 2 answers

Leah Fainchtein Buenavida

Tech Blogger

Oct 17, 2021

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper-converged infrastructure at scale. We looked into it but then ultimately chose Nutanix Acropolis. We liked Hyperflex’s virtualization feature and the unified network fabric it provides. The Integrated Managed Controller was a nice feature to have. It is expandable, stable, and has good redundancy. If you require more processor cores per box, Cisco HyperFlex is a good solution for you. Support will depend on the type of contract you have, with some requests taken care of immediately and others taking longer according to the engineer’s expertise. While Hyperflex is designed for any company size, I wouldn’t recommend them for small businesses. It also requires a solid knowledge of Cisco products, as the UI can be difficult to manage. Upgrading to a newer version can also be cumbersome and could use some improvement. We chose Nutanix because it is easier to use and is more cost-effective. Nutanix allows us to deploy, run and scale applications both on-premises and in the cloud. It has excellent support. You can log the query straight to a technical expert, which is good if you have staff not familiar with AOS. It is easy to scale by adding new nodes, and the company is constantly adding new features. Nutanix is not for everyone, though. The Nutanix Cloud System can be complex to maneuver when at the command line or when troubleshooting. Conclusions Nutanix is better for medium-sized companies and when you need a cost-effective solution. Cisco Hyperflex is a complete solution but is better suited for large enterprises. It works better if you are already a Cisco user.

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Steffen Hornung

Administrator at Neuberger Gebäudeautomation GmbH

Aug 2, 2022

With Nutanix you have the freedom of choice. You can deploy it with several server hardware vendors or completely in the cloud. I don’t know Hyperflex at heart, though. Also, support at Nutanix is outstanding.

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Top Industries

By visitors reading reviews

Computer Software Company

26%

Financial Services Firm

Government

Manufacturing Company

Educational Organization

37%

Computer Software Company

12%

Financial Services Firm

Manufacturing Company

Company Size

By reviewers

Large Enterprise

Midsize Enterprise

Small Business

Questions from the Community

How do I choose between Cisco Hyperflex HX Series and Nutanix Acropolis AOS?

Cisco HyperFlex HS series vs Nutanix Acropolis AOS Cisco HyperFlex gives extended hyper-convergence functions from core to edge and multi-cloud environments. It helps IT and OT teams deploy hyper...

See all answers

How does VxRail compare with Cisco HyperFlex HX Series?

VxRail provides stable solutions for technical problems while at the same time not being too expensive for a company to invest in. Even if you are working with a limited budget, this platform offer...

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What do you like most about Cisco HyperFlex HX-Series?

It's easy to get the tool started.

See all answers

What is the biggest difference between Nutanix Acropolis and VMware vSphere?

We found the reduced power consumption with Nutanix Acropolis AOS a very attractive feature. We also like the interface that allows you to talk directly to your VM from the present software. We fou...

See all answers

Which would you choose - Nutanix Acropolis AOS or VMware vSAN?

See all answers

What makes Nutanix Cloud Infrastructure (NCI) worth using?

NCI is a product with many tools and services but the one that, in my opinion, makes it better than similar products and worth using, is the full-stack lifecycle management. This capacity allows u...

See all answers

Comparisons

VMware vSAN vs Cisco HyperFlex HX-Series [EOL]

Compared 26% of the time

VxRail vs Cisco HyperFlex HX-Series [EOL]

Compared 22% of the time

HPE SimpliVity vs Cisco HyperFlex HX-Series [EOL]

Compared 18% of the time

Dell PowerFlex vs Cisco HyperFlex HX-Series [EOL]

Compared 12% of the time

HPE Alletra dHCI vs Cisco HyperFlex HX-Series [EOL]

Compared 7% of the time

More Cisco HyperFlex HX-Series [EOL] Competitors

VxRail vs Nutanix Cloud Infrastructure (NCI)

Compared 8% of the time

VMware vSphere vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Dell PowerFlex vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

HPE SimpliVity vs Nutanix Cloud Infrastructure (NCI)

Compared 6% of the time

Hyper-V vs Nutanix Cloud Infrastructure (NCI)

Compared 5% of the time

More Nutanix Cloud Infrastructure (NCI) Competitors

Product Reports

Buyer's Guide

Cisco HyperFlex HX-Series [EOL]

April 2025

Download Cisco HyperFlex HX-Series [EOL] product report

Buyer's Guide

Nutanix Cloud Infrastructure (NCI)

April 2025

Nutanix Cloud Infrastructure (NCI) report

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Also Known As

No data available

Nutanix Acropolis AOS, Nutanix AOS, Nutanix Acropolis

Overview

The Cisco HyperFlex HX Data Platform is a purpose-built, high-performance, scale-out file system with a wide array of enterprise-class data management services. The data platform’s innovations redefine distributed storage technology, giving you complete hyper-convergence with enterprise storage features:

Enterprise-class data management
Continuous data optimization
Securely encrypted storage
Dynamic data placement
Clusterwide parallel data distribution
Linear and incremental scaling
API-based data platform architecture
A simplified approach

Cisco

Nutanix Cloud Infrastructure (NCI) is a top-ranking HCI software, cloud management tool, and Software Defined Storage (SDS) tool that is marketed as the foundation for users' hybrid clouds. It offers a powerful and secure hyperconverged infrastructure to deliver all data and applications at any scale and on any cloud. The solution offers a complete software stack that allows users to unify their hybrid cloud infrastructure.

NCI’s services include computer, storage and network, hypervisors and containers, and deployment in public or in private clouds. The product also comes with built-in resilience, disaster recovery capabilities, self-healing, and high-security capacities. It provides further deployment flexibility through several software and hardware options and platforms. NCI includes a full set of enterprise capabilities. It can also be deployed on a wide range of servers from popular manufacturers.

The capabilities of the product are categorized into three main groups:

AOS storage
Flexible and open compute
Automated and secure networking

Outside of these categories, NCI also offers other capabilities:

Integrated disaster recovery
Full-stack lifecycle management
VMware with Nutanix
Intelligent operations

Nutanix Cloud Infrastructure (NCI) Features

Nutanix Cloud Infrastructure (NCI) offers its customers various features and tools in each of the previously mentioned categories. The available features for users currently include:

High-performance: This set of features utilizes hardware advances such as NVMe and RDMA to accelerate users' most demanding applications with consistent performance. The tools in this feature category work alongside data locality to ensure successful results.
Foolproof resiliency: These Nutanix Cloud Infrastructure features protect data and keep it available by facilitating advanced distributed consistency algorithms. Users can utilize these features to protect their data from issues like bit rot, hardware failures, and even entire site failure.
Flexibility: This set of features allows storage to be sized for the needs of each organization and expanded promptly and easily so that the organization and its data can grow. The features offer flexibility to users in terms of applying storage policies logically on a pre-workload basis, instead of being tied to hardware.
Hypervisor choice: Users can choose from the leading hypervisors - Microsoft Hyper-V or VMware ESXi. They can also leverage the built-in hypervisor AHV that Nutanix Cloud Infrastructure (NCI) provides.
Integrated virtualization: These features offer simplified automation and AHV streamlined operations. The services in this category are optimized for high performance and reliability.
Kubernetes: Nutanix Cloud Infrastructure (NCI) offers features to build and deploy cloud-native applications on intelligent distributed infrastructure. Apps can be integrated with cloud-compatible storage and both building and deployment can be achieved within the same platform.
Microsegmentation: Nutanix Cloud Infrastructure (NCI) offers features to prevent malware spread and reduce attack surfaces by leveraging machine learning (ML).
Virtual networking: This set of features allows users to easily implement multi-tenancy in their environment or stretch networks across clouds.
Centralized network management: Nutanix Cloud Infrastructure (NCI) provides organizations with a way to manage networking configurations centrally. Users can utilize it across their human-computer interaction (HCI) environment with simple virtual switch management.

Nutanix Cloud Infrastructure (NCI) Benefits

The product offers various benefits to users who utilize its capacities. Some of these include:

NCI reduces technology sprawl and frees up technical resources to allow organizations to focus on other activities, potentially reducing costs for the business.
The product allows customers to deploy, scale, and bridge to the public cloud to be able to react in evolving business environments.
Nutanix Cloud Infrastructure improves data availability while simultaneously protecting it against several kinds of failures and attacks.
The solution offers high-performance, resilient distributed storage for all workloads.
Working alongside Nutanix Cloud Platform, NCI offers simple management of data from one console.
Nutanix Cloud Infrastructure works by the zero trust philosophy, protecting users' apps and data through specially designed security protocols.

Reviews from Real Users

According to Gerhard J., an IT manager at Q4 Fuel, Nutanix Cloud Infrastructure (NCI) provides serious reliability and stability across the entire system makes for ROI.

A solutions architect at a computer software company describes NCI as a stable, straightforward to set up, and scalable solution.

Nutanix

Sample Customers

BluePearl Veterinary Partners, Ready Pac Foods, Bryant University, Bellevue Group, KPIT Technologies, City Harvest

St. Lukes Health System, the City of Seattle, Yahoo! Japan, Sligro, Empire Life, Hyundai AUS, and many others.

Find out what your peers are saying about Dell Technologies, VMware, Nutanix and others in HCI. Updated: March 2025.

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