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Microsoft Defender Threat Intelligence vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 23, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
8.0
Microsoft Defender Threat Intelligence offers major ROI by saving 62% on budgets and providing comprehensive threat protection and business value.
Sentiment score
8.1
ThreatLocker Zero Trust Platform enhances security, improves efficiency, saves costs, increases revenue, and supports business growth by reducing threats.
If something were to happen without ThreatLocker, the cost would be huge, and thus, having it is definitely worth it.
The main return on investment is peace of mind, knowing that with ThreatLocker on any endpoint, it will almost always block all malicious code or exploits, even zero-day exploits.
It keeps malware, Trojans, and ransomware at bay.
 

Customer Service

Sentiment score
7.4
Microsoft Defender support experiences vary; community platforms help, technical support is inconsistent, with level two proving effective.
Sentiment score
8.8
ThreatLocker Zero Trust's responsive customer service, highlighted by the Cyber Hero program, is praised for speed, professionalism, and effectiveness.
Level two support is knowledgeable and knows how the product works, which is very good.
They have been very responsive, helpful, and knowledgeable.
I would rate their customer support a ten out of ten.
Their support is world-class.
 

Scalability Issues

Sentiment score
7.8
Microsoft Defender Threat Intelligence is highly scalable, serving diverse businesses effectively, though costs may rise with increased users.
Sentiment score
8.2
ThreatLocker Zero Trust Platform offers seamless scalability and adaptability, efficiently managing diverse environments and dynamic growth across endpoints.
If there were some customizations available, I would rate its scalability as nine out of ten.
I started off with just the servers, and within a month and a half, I set up the entire company with ThreatLocker.
It seems to primarily operate on the endpoints rather than at a central location pushing out policies.
I would rate it a ten out of ten for scalability.
 

Stability Issues

Sentiment score
8.3
Microsoft Defender Threat Intelligence offers high reliability and performance, with occasional regional outages, comparable to Office 365 stability.
Sentiment score
7.5
ThreatLocker Zero Trust Platform is praised for stability and reliability, with minor issues swiftly addressed by support.
It provides a high level of security and avoids phishing and scam emails.
For five years, we have not had a problem.
Once deployed, it downloads the policies locally, so even if the computer doesn't have internet, it doesn't matter.
It has been very stable, reliable, and accessible.
 

Room For Improvement

Improving pricing, integration, stability, and support could enhance Microsoft Defender Threat Intelligence's market accessibility and effectiveness.
ThreatLocker needs UI improvements, better integrations, expanded training, enhanced analytics, restricted Learning Mode, and faster support.
Providing code customization would help keep pace with new vulnerabilities and threats.
Controlling the cloud environment, not just endpoints, is crucial.
This is problematic when immediate attention is needed.
Comprehensive 24-hour log monitoring is a valuable enhancement for both business and enterprise-level users.
 

Setup Cost

Microsoft Defender Threat Intelligence offers cost-effective bundling with E5 licenses, beneficial for enterprises but challenging for SMEs preferring E3.
Enterprise buyers find ThreatLocker's pricing competitive and flexible, valuing its affordability, transparency, and accessible setup costs.
After conversations with other partners, it became clear we underpriced it initially, which caused most of our issues.
We are moving towards the Unified solution, where they basically bundle everything together, providing us better stability with the ability to bring in new product offerings without having to go back to the customer and say, 'This is going to cost you.'
I had a really good deal at the time, and it continues to be cost-effective.
 

Valuable Features

Microsoft Defender Threat Intelligence offers advanced detection, seamless integration, robust security, proactive monitoring, and effective zero-day vulnerability management.
ThreatLocker Zero Trust Platform enhances security with features like application control, selective elevation, and robust network access controls.
One of the best features is that it provides a certain level of customization, allowing us to set our spam confidence levels.
ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent.
It protects our customers.
The major benefit is fewer breaches overall, as nothing can be run without prior approval. This helps my company protect its data and secure itself effectively.
 

Categories and Ranking

Microsoft Defender Threat I...
Ranking in Advanced Threat Protection (ATP)
11th
Average Rating
8.4
Reviews Sentiment
7.4
Number of Reviews
31
Ranking in other categories
Threat Intelligence Platforms (4th), Microsoft Security Suite (18th)
ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
6th
Average Rating
9.2
Reviews Sentiment
7.6
Number of Reviews
39
Ranking in other categories
Network Access Control (NAC) (5th), Endpoint Protection Platform (EPP) (6th), Application Control (2nd), ZTNA (3rd), Ransomware Protection (3rd)
 

Mindshare comparison

As of April 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender Threat Intelligence is 1.6%, up from 1.3% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 2.7%, up from 1.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Nim Nadarajah - PeerSpot reviewer
A native Microsoft solution the provides great ROI and continuously improves its offering
We have Microsoft bias. We generally don't have any significant negative feedback or improvement points around Defender, EDR and CMDR platforms. It does a good job across the board. The price point is something they can improve slightly for those who don't have an M 365 E5. I believe it's a $2.80 cents add-on. In Canadian, that's expensive. If they can drop it to a dollar, for those who don't have M 365 E5, they're going to open up market share and increase affordability for an entire market segment in the medium business category. Other than that, we have no major negative feedback.
Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Financial Services Firm
12%
Educational Organization
11%
Government
11%
Computer Software Company
37%
Retailer
8%
Manufacturing Company
5%
Financial Services Firm
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender Threat Intelligence?
It just runs in the background. I don't have to worry about, making sure it's Intelligence. So, you know, this kind of makes it very easy, have to worry about installing. It is easy to use.
What needs improvement with Microsoft Defender Threat Intelligence?
Some of the customization features could be improved by providing a portion of it as open source. This would allow integration with other solutions, enhancing Threat Intelligence. Providing code cu...
What is your primary use case for Microsoft Defender Threat Intelligence?
We are using Microsoft Defender ATP specifically as an email security solution, as well as for our critical servers as a web security solution. We have almost eleven hundred users utilizing it for ...
What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
We have encountered a few challenges regarding pricing, contract renewals, and additions. As we explored adding features like Cyber Hero, it proved to be an increased expense for our clients. This ...
What needs improvement with ThreatLocker Allowlisting?
I find that the learning mode is too accessible. Technicians sometimes default to it instead of manually building policy controls. I would prefer the learning mode to be harder to access, ideally h...
 

Also Known As

No data available
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

Find out what your peers are saying about Microsoft Defender Threat Intelligence vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: March 2025.
846,617 professionals have used our research since 2012.