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Microsoft Defender vs Proofpoint Email Protection comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Office 365 offers strong ROI through security enhancements, cost savings, and improved company productivity despite measurement challenges.
Sentiment score
5.9
Proofpoint Email Protection enhances security by reducing spam and threats, though its interface may impact operational efficiency.
It has also decreased our time to detection and response by about 15 to 20 percent.
Technology support manager at Alfred State College
Overall, cost of owning and operating our system goes down.
Designation Chief Consultant at Avtow
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
Chief Architect at a tech vendor with 1,001-5,000 employees
The ideal situation would be to have all these portals combined into one unified dashboard.
Information Security Architect at Loews Hotels
 

Customer Service

Sentiment score
5.8
Microsoft Defender for Office 365 users rate support highly, praising its responsiveness and 24/7 availability, despite occasional documentation and communication issues.
Sentiment score
6.9
Proofpoint Email Protection's support is often praised for expertise and responsiveness but criticized for inconsistencies and sluggish communication.
Over the past two years, there have been no critical problems.
Solution Consultant at BIM Group of Companies
we opened tickets, and they typically resolve them quickly.
Chief Architect at a tech vendor with 1,001-5,000 employees
With a subscription for Microsoft Defender for Office 365, it is an eight. Without it, it is a six.
Manager at a tech services company with 10,001+ employees
I am familiar with the granular policy control feature of Proofpoint Email Protection, and I find their support excellent for modifying those policies.
Senior Cybersecurity Specialist at a retailer with 10,001+ employees
I rate customer support a three out of ten mainly because of the phishing attacks that are getting through.
Information Security Architect at Loews Hotels
Sometimes I get some really great responses and analysts, but sometimes when their cloud services have a failure, they are slow to respond and tell me about it, though they have been improving.
Consultant at Exelixis Inc
 

Scalability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 offers scalable, efficient protection for large enterprises, ensuring seamless growth across diverse industries.
Sentiment score
7.6
Proofpoint Email Protection offers scalable, adaptable cloud-based architecture, efficiently supporting expansions for businesses of all sizes, despite minor licensing concerns.
We have never faced scalability problems, and Microsoft manages it effectively.
Solution Consultant at BIM Group of Companies
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
Chief Architect at a tech vendor with 1,001-5,000 employees
Microsoft Defender for Office 365 scales with the growing needs of my company well.
Senior Client Director and Advisory Service Leader at Crossfuze
Proofpoint is scalable for multi-site organizations with thousands of users.
Products and solutions director at ITVikings
Proofpoint Email Protection is a scalable solution that very much fits our capacity requirements.
Consultant at Exelixis Inc
 

Stability Issues

Sentiment score
7.7
Microsoft Defender for Office 365 provides 99.9% uptime with minor issues, ensuring reliable performance and seamless cloud integration.
Sentiment score
8.1
Proofpoint Email Protection offers consistent stability and reliability, with minor interface issues and infrequent outages reported by users.
I would rate the stability of Microsoft Defender for Office 365 as 10 over 10 because it's highly available, it works, and it does the job it is meant to do.
Cloud Solutions Architect at a tech services company with 201-500 employees
I have not experienced any downtime, crashes, or performance issues because of Defender.
Technology Associate at a financial services firm with 51-200 employees
The solution is stable, as we have been using it for the past two years.
Solution Consultant at BIM Group of Companies
When evaluating the stability of Proofpoint Email Protection in regards to downtime, bugs, and glitches, it comes and goes in waves.
Consultant at Exelixis Inc
 

Room For Improvement

Users call for enhanced virus detection, cross-platform support, and pricing transparency in Microsoft Defender for Office 365.
Proofpoint Email Protection's high cost and integration challenges hinder its usability, flexibility, and effectiveness in phishing and spam detection.
The main area for improvement is simplifying the implementation and rollout process.
Infrastructure and Security Lead at Vedanta
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
Solution Consultant at BIM Group of Companies
There is a different console for different things; I just want one consolidated console.
Senior Director, Security Architecture & Engineering at a leisure / travel company with 10,001+ employees
Proofpoint could expand its phishing detection capabilities to improve its efficiency.
Products and solutions director at ITVikings
More security could be implemented.
Logistics Manager at a educational organization with 501-1,000 employees
Proofpoint Email Protection can improve in how it analyzes alerts by using more AI within its product suite to eliminate repeat alerts, such as filtering down the same attack to generate only one alert.
Information Security Architect at Loews Hotels
 

Setup Cost

Microsoft Defender for Office 365 pricing is seen as flexible but potentially expensive, offering value in comprehensive security features.
Proofpoint Email Protection is costly but valued for its robust features despite higher pricing than competitors like Mimecast and Barracuda.
We've likely saved 30% of costs.
Designation Chief Consultant at Avtow
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Infrastructure and Security Lead at Vedanta
Microsoft is quite affordable with a lot of features available for any size organization.
Solution Consultant at BIM Group of Companies
Customers pay around $90,000 yearly for a 1,000-user organization, with the subscription license being the main expense, apart from implementation fees.
Products and solutions director at ITVikings
Additional costs do come in, but it enhances security.
Logistics Manager at a educational organization with 501-1,000 employees
 

Valuable Features

Microsoft Defender for Office 365 enhances email security with anti-phishing, anti-malware, threat intelligence, and seamless integration for efficient management.
Proofpoint Email Protection offers robust security, AI-driven threat detection, user-friendly management, and strong support for email threat visibility.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
Technology support manager at Alfred State College
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
Solution Consultant at BIM Group of Companies
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
Chief Architect at a tech vendor with 1,001-5,000 employees
The main feature I find most effective is that Proofpoint Email Protection scans emails and quarantines the doubtful ones.
Logistics Manager at a educational organization with 501-1,000 employees
The most beneficial feature of Proofpoint Email Protection is mostly spam filtering; it was very efficient, and we were very happy with the functionality as only relevant emails were allowed for mailboxes.
Manager, IT Director at Cakmak Avukatlik Ortakligi
I appreciate that it's the industry leader, and its firewalling is very easy to manage and implement.
Senior Cybersecurity Specialist at a retailer with 10,001+ employees
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Email Security
1st
Ranking in Advanced Threat Protection (ATP)
2nd
Ranking in Secure Email Gateway (SEG)
1st
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Microsoft Security Suite (10th)
Proofpoint Email Protection
Ranking in Email Security
2nd
Ranking in Advanced Threat Protection (ATP)
4th
Ranking in Secure Email Gateway (SEG)
2nd
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
55
Ranking in other categories
Digital Risk Protection (3rd), Office 365 Protection (2nd)
 

Mindshare comparison

As of January 2026, in the Secure Email Gateway (SEG) category, the mindshare of Microsoft Defender for Office 365 is 24.2%, down from 31.1% compared to the previous year. The mindshare of Proofpoint Email Protection is 20.3%, up from 20.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Secure Email Gateway (SEG) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 36524.2%
Proofpoint Email Protection20.3%
Other55.5%
Secure Email Gateway (SEG)
 

Q&A Highlights

Aishwarya Rm - PeerSpot reviewer
Senior Software Engineer at Capgemini
Dec 30, 2024
 

Featured Reviews

Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
Steve Bradbury - PeerSpot reviewer
Consultant at Exelixis Inc
Email defenses have blocked advanced threats and provide deep visibility into risky users
The areas that have room for improvement in Proofpoint Email Protection include their cost of ownership, which is fairly high. To manage and run all their products, I have to list and manage administrators in seven or eight different places. That is too many places to keep track of since for this tool I have to go to one location, and for another tool I have to go to a different location. They need to simplify the administration management of administrators and consolidate that into one place for all their products. Access to all the different products is very scattered. For some products I go to one URL, and for different products I go to a different URL. They have a threat URL that has most of their products in it, but not all. They need to simplify the interface to show all the products I have access to in one location.
report
Use our free recommendation engine to learn which Secure Email Gateway (SEG) solutions are best for your needs.
881,036 professionals have used our research since 2012.
 

Answers from the Community

Aishwarya Rm - PeerSpot reviewer
Senior Software Engineer at Capgemini
Mar 3, 2023
Mar 3, 2023
In my opinion, there is little comparison. Proofpoint is an industry leader in email protection and has a very tightly integrated ecosystem for email defense, incident response, and awareness training. They have dedicated teams monitoring the threat landscape and continually tweak their algorithms to match current threats. Proofpoint goes far beyond email protection with tools to help your t...
See 2 answers
JB
Security Engineer at Kforce
Mar 2, 2023
In my opinion, there is little comparison. Proofpoint is an industry leader in email protection and has a very tightly integrated ecosystem for email defense, incident response, and awareness training. They have dedicated teams monitoring the threat landscape and continually tweak their algorithms to match current threats. Proofpoint goes far beyond email protection with tools to help your team investigate email-related threats, monitor user interactions and risks, act on users who continually handle email improperly with training, simulated phishes for user awareness, and even tools to reach full DMARC and DKIM protection (which can be extremely time and labor intensive). Defender has very little footprint, but also offers far less features. Proofpoint can be a more costly solution, but when compared feature for feature it far outweighs Defender. We do use both at my organization and I rarely interact with Defender as part of email investigations. Both will offer great protection, but beyond that Proofpoint is very feature rich and gives my team more tools to combat email threats when something is not caught by the gateway rules. Quite often emails do not contain threats prior to delivery and are weaponized afterward to get past the email defenses. Proofpoint has TAP and TRAP to isolate and remove those threats once they do become weaponized; along with the intelligence to know it has occurred. Proofpoint also has stellar reporting features so you have a very good understanding of your email environment at a glance.
Remy Ma - PeerSpot reviewer
Network Security Services at ACE Managed Securty Services
Mar 3, 2023
If you're looking for Managed Email Security, it can be hard to decide between Microsoft Defender for Office 365 and Proofpoint Email Protection. It's like choosing between two delicious flavors of ice cream — both are good, but what flavor do you prefer? Microsoft Defender for Office 365 is managed by Microsoft’s Security & Compliance Center and provides managed email security for Office 365 customers. It offers comprehensive protection against malicious emails, phishing attacks, and other advanced threats. On the other hand, Proofpoint Email Protection is managed by a third-party provider and provides managed email security for businesses of all sizes. While it doesn't have as many features as Defender, Proofpoint still offers robust protection against malicious emails, phishing attacks, and other advanced threats. In the end, it comes down to personal preference. Do you prefer managed email security managed by Microsoft or a third party? It all depends on your individual needs. Whichever solution you choose, make sure that managed email security meets all of your requirements!
 

Top Industries

By visitors reading reviews
Computer Software Company
14%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Financial Services Firm
11%
Computer Software Company
11%
Manufacturing Company
9%
Comms Service Provider
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise14
Large Enterprise18
 

Questions from the Community

What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What is your primary use case for Microsoft Defender for Office 365?
My use case for Microsoft Defender for Office 365 is for email protection, safe links, protection of links, documents, protecting my documents, and protecting attachments. I also use it to conduct ...
What is your experience regarding pricing and costs for Proofpoint Email Protection?
In terms of pricing, it is okay compared to others. I would say it is normal. Additional costs do come in, but it enhances security.
What needs improvement with Proofpoint Email Protection?
I believe they still need to improve by consolidating some portals, as currently, you have to log in separately to a few of them.
 

Also Known As

MS Defender for Office 365
Proofpoint Enterprise Protection, Proofpoint Digital Protection
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Proofpoint Email Protection and other solutions. Updated: January 2026.
881,036 professionals have used our research since 2012.