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Microsoft Defender vs Proofpoint Email Protection comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
21st
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (15th), Data Loss Prevention (DLP) (20th), Cloud Access Security Brokers (CASB) (11th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (13th), Access Management (13th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
63
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (9th), Secure Email Gateway (SEG) (1st)
Proofpoint Email Protection
Ranking in Email Security
1st
Average Rating
8.4
Reviews Sentiment
6.7
Number of Reviews
98
Ranking in other categories
Advanced Threat Protection (ATP) (3rd), Digital Risk Protection (3rd), Office 365 Protection (1st), Secure Email Gateway (SEG) (2nd)
 

Q&A Highlights

Aishwarya Rm - PeerSpot reviewer
Senior Software Engineer at Capgemini
Dec 30, 2024
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
Vivek_Jaiswal - PeerSpot reviewer
Cyber Security Senior Specialist at a tech vendor with 10,001+ employees
Advanced email defenses have protected healthcare staff and simplified incident response
There are many things that could be improved, but once you are very well-known about this application, you could perform that improvement plan. There are many scenarios where I have worked with Proofpoint Email Protection where a requirement was not fulfilled due to the limitation of the product. For example, we have Report Phish automation. With Proofpoint Email Protection, we can configure Report Phish and forward the email to any email addresses or shared mailboxes that we provide in the configuration. That email is forwarded as is with whatever the user reports as a phishing email. However, some organizations do not want the reported phishing email to go as is into their ticketing tool because it might contain malicious attachments and malicious links that are not required to go into their internal organization. Proofpoint Email Protection has that limitation. They cannot forward or restrict, but could forward only limited information such as some header information, sender subject details, or only limited information. As it is, the email can be forwarded, not as limited information. Proofpoint TRAP solution also has limitations. It cannot create alert notifications for some specific requirements because Proofpoint works the way it is designed, and if you want it to work based on our requirement, that should not be possible. There is a scope of limitations here. There are many improvements that should be made. First, they should work on their false positive minimization. Proofpoint generally takes all emails, investigates them, and classifies them. There are many situations where legit emails are blocked because that domain is found to be under a malicious category somehow, but actually it is not. False positive minimization could be improved, and they could enhance their other applications or solutions. There are many things that they could improve from each application and each portal.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution has different options that can be used to differentiate DDoS attacks."
"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."
"It's the endpoint exposition. We don't need to expose our VPN server to the internet and need a zero-test solution. I can apply some conditional access to the endpoint that's connecting to our network to check their security policies or the security condition of their workstation. Once the workstation is trying to connect to my internal network, then I would like to check the discrete condition of these endpoints that are trying to access my internal network. We created some conditional access. We have CrowdStrike, to check if the CrowdStrike is installed, to check if it's updated, and to check for Windows updates. We created some conditional policies to check it."
"It's a perfect solution from my perspective; it's easy to understand and easy to configure."
"This solution is easy to understand and easy to configure."
"Cloudflare Access is part of the Zero Trust philosophy."
"What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection."
"Using Cloudflare One makes my work quite easy because for DDoS protection, all I need to do is understand the OSI model and click; it makes it easier than trying to write a command line or use a Linux command."
"Microsoft Defender for Office 365's most valuable feature is its performance."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"It gives us visibility into threats and, for endpoints, it helps us to prioritize threats. We used to have a lack of visibility, but now our time to detect and respond has decreased."
"Technical support is very good. They are knowledgeable and respond quickly."
"It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment."
"Microsoft Defender for Office 365's most valuable features are safe attachments and safe links."
"The most valuable feature of Microsoft Defender for Office 365 is data backups that we can provide through ticket requests."
"The deployment capability is a great feature, and we're able to activate this feature throughout France with a click."
"At this point in time, there's nothing that needs to be changed or improved in the tool."
"It was easy to set up."
"They have customized security rules, mature rules, anti-virus protection, as well as email authentication similar to SPF, DKIM, and DMARC."
"We have noticed a huge improvement in productivity of the users by clearing up their inbox of malicious emails and spam, and it has also prevented and secured our environment on a daily basis, making the security team's job much easier."
"Proofpoint Email Protection has definitely impacted my organization positively."
"It has been comprehensive and easy to use for both users and administrators."
"Proofpoint Email Protection is a good product, and its most beneficial feature is the Threat Response Auto-Pull. I also like that it's an integrated email security solution."
"Proofpoint Email Protection has reduced the analyst overhead in responding to phishing incidents by several orders of magnitude."
 

Cons

"There are premium tier live service and lower tier live service, so we opted for the lower tier. But there is no medium tier where we pay a little extra and get a bit more service. So if that can be improved."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"Our subscription plan for the solution has a limitation of bot signatures."
"Cloudflare DDoS has poor technical support."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"The response time for support must be reduced."
"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions."
"There is room for improvement in terms of reporting."
"We need a separate license and we don't know how to get the license that is required."
"Specifically, within Microsoft Defender for Office 365, I want it to improve the DLP capabilities."
"We are always looking for others tools to increase automation on tasks. There can be better integration with other solutions, such as PowerPoint and email."
"They have moved features from one console to another. Things have been moved around in the interface and it takes me time to find where certain features are."
"Microsoft needs to broaden its global support presence by establishing teams of subject-matter experts in all regions."
"The visibility into threats is not up to the mark, as I do not have control. I rate my experience with Microsoft Defender for Office 365 as six out of ten due to troubleshooting and pricing concerns."
"The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster."
"The largest complaint that we hear from our customers is that there is no local support."
"Proofpoint has a lot of false alarms."
"Proofpoint Email Protection's interface is confusing and could be improved."
"It's scalable, but the devil's in the details — you have to know your email volumes."
"I would like to see improvements in Proofpoint Email Protection's portal as it is sometimes slow."
"The false positives are an issue."
"Everything with Proofpoint Email Protection has room for improvement in my opinion."
"While ingesting the logs into our SIEM tool, most organizations don't have the capability to buy the email gateway as it is quite an expensive one."
 

Pricing and Cost Advice

"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"Cloudflare Zero Trust Platform's pricing is good."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The solution is not that expensive."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"The license is expensive because the cost is based on the number of users."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"The pricing has become expensive."
"It is expensive."
"The end customer is buying our solution, which can be for monthly or annual usage depending on our payment and business model."
"The price is reasonable."
"We sell annual licenses for this solution."
"In general, the pricing is competitive."
"Proofpoint Email Protection is a reasonably priced product, which means that it is neither too low nor too high in terms of price."
"I rate the price of Proofpoint Email Protection a four out of five."
"It is multiple times more expensive, which made it very much less attractive."
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Answers from the Community

Aishwarya Rm - PeerSpot reviewer
Senior Software Engineer at Capgemini
Mar 3, 2023
Mar 3, 2023
In my opinion, there is little comparison. Proofpoint is an industry leader in email protection and has a very tightly integrated ecosystem for email defense, incident response, and awareness training. They have dedicated teams monitoring the threat landscape and continually tweak their algorithms to match current threats. Proofpoint goes far beyond email protection with tools to help your t...
See 2 answers
JB
Security Engineer at Kforce
Mar 2, 2023
In my opinion, there is little comparison. Proofpoint is an industry leader in email protection and has a very tightly integrated ecosystem for email defense, incident response, and awareness training. They have dedicated teams monitoring the threat landscape and continually tweak their algorithms to match current threats. Proofpoint goes far beyond email protection with tools to help your team investigate email-related threats, monitor user interactions and risks, act on users who continually handle email improperly with training, simulated phishes for user awareness, and even tools to reach full DMARC and DKIM protection (which can be extremely time and labor intensive). Defender has very little footprint, but also offers far less features. Proofpoint can be a more costly solution, but when compared feature for feature it far outweighs Defender. We do use both at my organization and I rarely interact with Defender as part of email investigations. Both will offer great protection, but beyond that Proofpoint is very feature rich and gives my team more tools to combat email threats when something is not caught by the gateway rules. Quite often emails do not contain threats prior to delivery and are weaponized afterward to get past the email defenses. Proofpoint has TAP and TRAP to isolate and remove those threats once they do become weaponized; along with the intelligence to know it has occurred. Proofpoint also has stellar reporting features so you have a very good understanding of your email environment at a glance.
Remy Ma - PeerSpot reviewer
Network Security Services at ACE Managed Securty Services
Mar 3, 2023
If you're looking for Managed Email Security, it can be hard to decide between Microsoft Defender for Office 365 and Proofpoint Email Protection. It's like choosing between two delicious flavors of ice cream — both are good, but what flavor do you prefer? Microsoft Defender for Office 365 is managed by Microsoft’s Security & Compliance Center and provides managed email security for Office 365 customers. It offers comprehensive protection against malicious emails, phishing attacks, and other advanced threats. On the other hand, Proofpoint Email Protection is managed by a third-party provider and provides managed email security for businesses of all sizes. While it doesn't have as many features as Defender, Proofpoint still offers robust protection against malicious emails, phishing attacks, and other advanced threats. In the end, it comes down to personal preference. Do you prefer managed email security managed by Microsoft or a third party? It all depends on your individual needs. Whichever solution you choose, make sure that managed email security meets all of your requirements!
 

Top Industries

By visitors reading reviews
Construction Company
21%
Comms Service Provider
10%
Financial Services Firm
8%
Manufacturing Company
6%
Computer Software Company
12%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
7%
Financial Services Firm
12%
Manufacturing Company
9%
Computer Software Company
8%
Comms Service Provider
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise2
Large Enterprise11
By reviewers
Company SizeCount
Small Business25
Midsize Enterprise11
Large Enterprise31
By reviewers
Company SizeCount
Small Business29
Midsize Enterprise24
Large Enterprise50
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
What is your experience regarding pricing and costs for Proofpoint Email Protection?
This is not something that I deal with regarding pricing, setup cost, and licensing.
What needs improvement with Proofpoint Email Protection?
I would like to see improvements in the transition from Proofpoint Protection Server to Proofpoint on Demand because ...
What is your primary use case for Proofpoint Email Protection?
In my environment, I am using Proofpoint Email Protection for advanced email threat protection. For malware, spam, an...
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
MS Defender for Office 365
Proofpoint Enterprise Protection, Proofpoint Digital Protection
 

Overview

 

Sample Customers

23andMe
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Blocket, University of Waterloo, Lincoln Memorial University, WellSpan Health, U-Haul, Carestream Health, Westinghouse
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Proofpoint Email Protection and other solutions. Updated: April 2026.
892,287 professionals have used our research since 2012.