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Microsoft Defender for Office 365 vs Trellix Collaboration Security comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Office 365 offers strong ROI through security enhancements, cost savings, and improved company productivity despite measurement challenges.
Sentiment score
7.5
Trellix Collaboration Security improved efficiency and reduced staffing needs, despite costly training impacting ROI for some businesses.
It has also decreased our time to detection and response by about 15 to 20 percent.
Technology support manager at Alfred State College
Overall, cost of owning and operating our system goes down.
Designation Chief Consultant at Avtow
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
Chief Architect at a tech vendor with 1,001-5,000 employees
With Trellix Collaboration Security's endpoint telemetry, policy automation, and faster threat correlation, our team spent around 25 to 35% less time on routine investigations.
Cybersecurity Engineer Lead at Johnson & Johnson
I have seen a return on investment with Trellix Collaboration Security; specifically, money was saved and fewer employees were needed because I do not need employees on different sites.
Network & Security Lead at a computer software company with 1-10 employees
I observe that the return on investment is hindered by the lack of adequate training opportunities, with Trellix's own training being quite costly, ranging from 2,000 to 4,000 dollars, which many small or medium-sized businesses cannot afford.
Endpoint Security Analyst at BNP Paribas
 

Customer Service

Sentiment score
5.8
Microsoft Defender for Office 365 users rate support highly, praising its responsiveness and 24/7 availability, despite occasional documentation and communication issues.
Sentiment score
6.4
Trellix Collaboration Security's support receives mixed reviews, with premium options praised; concerns exist about global support efficiency.
Over the past two years, there have been no critical problems.
Solution Consultant at BIM Group of Companies
we opened tickets, and they typically resolve them quickly.
Chief Architect at a tech vendor with 1,001-5,000 employees
With a subscription for Microsoft Defender for Office 365, it is an eight. Without it, it is a six.
Manager at a tech services company with 10,001+ employees
My contract of support at Santander and BNP was a platinum support level, and with that, we really had a good experience.
Cybersecurity Engineer Lead at Johnson & Johnson
My experience with the Indian support team was not as satisfactory since they did not provide adequate support to rectify issues.
Network & Security Lead at a computer software company with 1-10 employees
The support isn't bad, but there is room for improvement in response time.
Cyber Security Engineer at a tech services company with 11-50 employees
 

Scalability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 offers scalable, efficient protection for large enterprises, ensuring seamless growth across diverse industries.
Sentiment score
7.9
Trellix Collaboration Security is scalable and integrates well, though licensing can be challenging for growing organizations.
We have never faced scalability problems, and Microsoft manages it effectively.
Solution Consultant at BIM Group of Companies
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
Chief Architect at a tech vendor with 1,001-5,000 employees
Microsoft Defender for Office 365 scales with the growing needs of my company well.
Senior Client Director and Advisory Service Leader at Crossfuze
Scalability benefits me by allowing for growth.
Cyber Security Engineer at a tech services company with 11-50 employees
The console is strong and can be used for a large quantity of machines without slowing down.
Cybersecurity Engineer Lead at Johnson & Johnson
Trellix Collaboration Security scalability allows me to use sensors on-cloud, on-premises, inside premises, and in a hybrid environment.
Network & Security Lead at a computer software company with 1-10 employees
 

Stability Issues

Sentiment score
7.7
Microsoft Defender for Office 365 provides 99.9% uptime with minor issues, ensuring reliable performance and seamless cloud integration.
Sentiment score
8.1
Trellix Collaboration Security is generally stable and reliable, though some face integration challenges affecting performance.
I would rate the stability of Microsoft Defender for Office 365 as 10 over 10 because it's highly available, it works, and it does the job it is meant to do.
Cloud Solutions Architect at a tech services company with 201-500 employees
I have not experienced any downtime, crashes, or performance issues because of Defender.
Technology Associate at a financial services firm with 51-200 employees
The solution is stable, as we have been using it for the past two years.
Solution Consultant at BIM Group of Companies
Sometimes, integration can be challenging, impacting its stability.
Cyber Security Engineer at a tech services company with 11-50 employees
 

Room For Improvement

Users call for enhanced virus detection, cross-platform support, and pricing transparency in Microsoft Defender for Office 365.
Trellix Collaboration Security needs improved reporting, spam detection, integration, customization, and virus/spam features, addressing performance and language support issues.
The main area for improvement is simplifying the implementation and rollout process.
Infrastructure and Security Lead at Vedanta
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
Solution Consultant at BIM Group of Companies
There is a different console for different things; I just want one consolidated console.
Senior Director, Security Architecture & Engineering at a leisure / travel company with 10,001+ employees
I would like to see the addition of email digital protection features, such as anti-spam and antivirus, not just sandboxing, in the on-premises solution.
Senior Team Leader at BMB
To improve vulnerabilities, Trellix can use an automation process to check if the system is vulnerable.
Network & Security Lead at a computer software company with 1-10 employees
Trellix Collaboration Security can be improved by making the reporting and analysis tools more detailed.
Sr Network & System Engineer at a tech services company with 11-50 employees
 

Setup Cost

Microsoft Defender for Office 365 pricing is seen as flexible but potentially expensive, offering value in comprehensive security features.
Trellix Collaboration Security is costly yet valued for multi-year licensing, challenging smaller businesses despite reasonable setup costs.
We've likely saved 30% of costs.
Designation Chief Consultant at Avtow
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Infrastructure and Security Lead at Vedanta
Microsoft is quite affordable with a lot of features available for any size organization.
Solution Consultant at BIM Group of Companies
It is quite expensive and should be reconsidered.
Cyber Security Engineer at a tech services company with 11-50 employees
The setup cost was very cheap.
Network & Security Lead at a computer software company with 1-10 employees
My experience with pricing, setup cost, and licensing for Trellix Collaboration Security is that pricing and setup were reasonable and licensing was straightforward.
Sr Network & System Engineer at a tech services company with 11-50 employees
 

Valuable Features

Microsoft Defender for Office 365 enhances email security with anti-phishing, anti-malware, threat intelligence, and seamless integration for efficient management.
Trellix Collaboration Security offers easy integration, advanced threat detection, auto-remediation, and customizable dashboards, enhancing overall security and collaboration.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
Technology support manager at Alfred State College
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
Solution Consultant at BIM Group of Companies
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
Chief Architect at a tech vendor with 1,001-5,000 employees
Another feature I believe is very important is the real-time response capability. It is possible to collect artifacts, run scripts, kill processes, and isolate machines all without leaving the interface.
Cybersecurity Engineer Lead at Johnson & Johnson
One of the most valuable features is the protection against vulnerabilities, particularly through virtual patching.
Cyber Security Engineer at a tech services company with 11-50 employees
The entire system is stable and delivers what the customer needs.
Senior Team Leader at BMB
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Email Security
1st
Ranking in Secure Email Gateway (SEG)
1st
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
60
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (10th)
Trellix Collaboration Security
Ranking in Email Security
11th
Ranking in Secure Email Gateway (SEG)
6th
Average Rating
8.8
Reviews Sentiment
6.9
Number of Reviews
19
Ranking in other categories
Instant Communications Security and Compliance (2nd), AI Security (11th)
 

Mindshare comparison

As of January 2026, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 9.6%, down from 13.9% compared to the previous year. The mindshare of Trellix Collaboration Security is 2.0%, down from 2.2% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Office 3659.6%
Trellix Collaboration Security2.0%
Other88.4%
Email Security
 

Featured Reviews

Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
FA
Cybersecurity Engineer Lead at Johnson & Johnson
Real-time threat response has boosted detection accuracy and reduces manual investigation work
I have had challenges in the past with Trellix Collaboration Security for implementation because of issues related to compatibility. Since we worked in a global company with different operating systems, it was necessary to create different plans and different actions to implement the product.One thing I really do not prefer in Trellix Collaboration Security is not related to the console. I am a McAfee fan since the McAfee tool, and I find the console of Trellix Collaboration Security to be very user-friendly and easy to use. However, I do not know if it is related to the architecture of the product. Of course, we have modern threats based on behaviors and zero days. We have today CrowdStrike and SentinelOne, where we have better results based on threats and behavior, where it is possible to create a simulation environment based on the file detected and based on it, confirm if it really is malicious or not. In general, I believe Trellix Collaboration Security improved the console based on the last console of McAfee, but I think it is possible to improve more. It really is a good product, but in my view, it needs to improve detection based on behaviors. Regarding automations, I have implemented Trellix Collaboration Security here at Johnson & Johnson, and I implemented it in the same situation at Santander Bank and BNP Paribas Bank, where I created automations to export data for different metrics, including malicious detections, compliance, baselines, scans, last scans based on the seven days, and checking of patterns. I export everything to CSV files. Based on that, I create Power BI dashboards, and in these Power BI dashboards, I have a more executive view for different metrics to provide to myself, my manager, or director to create an executive view based on it. Another important point we use here at Johnson & Johnson and other companies is a data hub or a SIEM solution, such as Elastic or ArcSight, where we select some logs to be sent and use it to build reports and metrics.
report
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879,455 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Computer Software Company
15%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
6%
Manufacturing Company
17%
Comms Service Provider
11%
Healthcare Company
11%
Computer Software Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise10
Large Enterprise31
By reviewers
Company SizeCount
Small Business8
Midsize Enterprise4
Large Enterprise10
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What needs improvement with Microsoft Defender for Office 365?
The inbuilt analysis of false positives can be faster. It's not slow, but it can be faster.
What do you like most about FireEye Email Security?
One of the valuable features of the product stems from the fact that it is easy to implement the tool in our environment.
What needs improvement with FireEye Email Security?
I have had challenges in the past with Trellix Collaboration Security for implementation because of issues related to compatibility. Since we worked in a global company with different operating sys...
What is your primary use case for FireEye Email Security?
In my field, I have been in the information security area for 17 years, and I am currently working in my position for a year and a half.I have worked with Trellix Collaboration Security for several...
 

Also Known As

MS Defender for Office 365
FireEye Email Security
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Northshore Utility District, Luz Technologies, Air Academy Federal Credit Union, Bank Gutmann, Bank of Thailand, Penn State Health Milton S. Hershey Medical Center, State of Missouri, City and County of San Francisco, Denver Public Schools, Vodafone, Go Auto, Stater Bros. Market
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Collaboration Security and other solutions. Updated: December 2025.
879,455 professionals have used our research since 2012.