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Cisco Secure Email Threat Defense vs Vade for M365 comparison

 

Comparison Buyer's Guide

Executive Summary

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
27th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Vade for M365
Ranking in Email Security
40th
Average Rating
0.0
Reviews Sentiment
7.4
Number of Reviews
1
Ranking in other categories
Office 365 Protection (9th)
 

Mindshare comparison

As of October 2025, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 0.9% compared to the previous year. The mindshare of Vade for M365 is 0.8%, down from 0.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Cisco Secure Email Threat Defense1.1%
Vade for M3650.8%
Other98.1%
Email Security
 

Featured Reviews

Enrique-Diaz Jolly - PeerSpot reviewer
Provides comprehensive threat protection with suggestions for modernizing controls
I use the email gateway as the core of the email exchange between the Internet and our domain. The email gateway serves as the email exchanger The product offers protection, email security, anti-spam, and antivirus. It includes threat intelligence with advanced malware protection and many…
Bruno Rolland - PeerSpot reviewer
A stable tool capable of detecting malware while focusing on anti-phishing to protect its users
I don't see ISO 27001 in the solution. While working on the solution, sometimes a customer needs to have a conformity level of SOC 1 or SOC 2 or some other conformity level. I did not see the aforementioned conformity levels added to the solution. Concerning a bank, data can be confidential, and when a bank needs to transfer such data, it has to be specific to a certain level of conformity, which I did not see in the product. Vade needs to incorporate the aforementioned aspects to improve their solution.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution is stable."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"The product offers protection, email security, anti-spam, and antivirus."
"It's very easy to deploy and configure."
"I highly recommend it as one of the best choices."
"It has an efficient email filtering feature."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"It is a stable solution...My company has no worries about the deployment phase of Vade for Office 365."
 

Cons

"This solution could be improved by integration with Sandbox."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The solution is a bit expensive."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned."
"Concerning a bank, data can be confidential, and when a bank needs to transfer such data, it has to be specific to a certain level of conformity, which I did not see in the product."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"Vade for Office 365 is a solution offered at competitive prices in the market...Payment has to be made for the whole bundle of Vade products."
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Top Industries

By visitors reading reviews
Computer Software Company
19%
Healthcare Company
8%
Manufacturing Company
7%
Financial Services Firm
7%
Computer Software Company
18%
Comms Service Provider
13%
Insurance Company
11%
Real Estate/Law Firm
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
No data available
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
Ask a question
Earn 20 points
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Vade for Office 365, Vade Secure Office 365
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
HTG 360, Weida IT Solutions, KVC Health Systems
Find out what your peers are saying about Microsoft, Abnormal AI, Proofpoint and others in Email Security. Updated: September 2025.
872,019 professionals have used our research since 2012.