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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
7th
Average Rating
8.2
Reviews Sentiment
6.7
Number of Reviews
41
Ranking in other categories
Anti-Malware Tools (12th)
 

Mindshare comparison

As of January 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 4.4%, down from 7.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Exchange Online Protection (EOP)4.4%
Cisco Secure Email Threat Defense1.1%
Other94.5%
Email Security
 

Featured Reviews

reviewer2541525 - PeerSpot reviewer
Principal Cyber Prevent and Defense Engineer at a comms service provider with 1,001-5,000 employees
Clawback feature performs well but analytics and integration capabilities need improvement
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty in sending logs to our SIEM. Cisco Secure Email Threat Defense's flexibility could be enhanced while it mostly integrates with cloud solutions, but not on-premise. The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious. Regarding room for improvement, the significant number of false positives should be addressed. The solution does not adapt to behavioral analytics and does not make changes when it sees a pattern.
HP
Cloud Consultant at Ensono
Service provider benefits from effective email security management and seeks enhanced customer support
Reporting could be one of the areas for improvement, as they could put more reporting into Microsoft Exchange Online Protection (EOP) natively rather than requiring additional licensing or connecting to other parts of the Microsoft suite, but it depends on the license you have. There aren't significant concerns with Microsoft Exchange Online Protection (EOP), as it depends on what customers expect; if they expect more features, then it depends on what Microsoft 365 license they have. The important thing is to ensure they are using all the security features they get with their licensing. The basic one is Microsoft Exchange Online Protection (EOP). While it's nice to have more functionality, that's available through other licensing programs with Microsoft. While we'd prefer more features, as a basic tool, it's fine, but more advanced features come with the add-ons from other parts of the Microsoft 365 licensing. One feature that could improve Microsoft Exchange Online Protection (EOP) is automated malware detection, where it actually analyzes the file offline in a sandbox to determine if it's safe, potentially reducing false positives.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"It has an efficient email filtering feature."
"The advanced threat analytics and URL filtering in threat detection are good features that are working well."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"I highly recommend it as one of the best choices."
"The solution is stable."
"The product offers protection, email security, anti-spam, and antivirus."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The security features provided by Microsoft are robust."
"We use the solution in all our environments. We use it for remedy tickets and give them updates. It was our main communication point."
"Microsoft EOP's most valuable feature is a shared mailbox."
"I like the product's ZAP feature."
"We can migrate seamlessly without any disruptions to our operations."
"The initial setup of Microsoft Exchange Online Protection was easy."
"We like the holding facility that is available for potentially suspicious URL's. This allows a real-time review to be performed before the email reaches a users inbox."
"With Microsoft Exchange Online Protection, if malware is attached to a mailer, it's very easy to go into the incident alert and find out what's happening with that identity and the mail."
 

Cons

"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The pricing could always be better."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"We encounter issues while searching for missing emails."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The solution is a bit expensive."
"It doesn't protect against everything. We do need protection for, for example, endpoints."
"The security features could be better."
"It wasn't easy or intuitive enough for me to start using it. So, the reason was that the solution changed."
"The solution needs to improve its backup."
"Some of the searchability when looking for specifics in Exchange logs is tedious."
"Online Protection has an issue in that it doesn't provide an option to stop impersonation."
"Having orchestration features added to Microsoft Exchange Online Protection, particularly automation and remediation, would be quite useful."
"It would be helpful for customers if Plan 1 features were included with EOP."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The product is bundled with Microsoft 365."
"The price could be lower."
"Apart from the license fee for the solution, there are no additional costs."
"It's a high price."
"It is a low-price solution."
"The solution should reduce the cost."
"Microsoft Exchange Online Protection's pricing is a little bit more because its price has recently increased."
"The product is expensive."
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Manufacturing Company
8%
Marketing Services Firm
8%
Healthcare Company
7%
Computer Software Company
11%
Financial Services Firm
10%
Manufacturing Company
8%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise7
Large Enterprise10
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
The user interface of Microsoft Exchange Online Protection (EOP) has room for improvement, as at times it doesn't make sense where to go to access certain features.
What is your primary use case for Microsoft Exchange Online Protection?
My use case for Microsoft Exchange Online Protection (EOP) is basically to protect ourselves from phishing emails and to improve our email security.
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: December 2025.
880,685 professionals have used our research since 2012.