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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

Why PeerSpot?
 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
22nd
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
10th
Average Rating
8.2
Reviews Sentiment
6.6
Number of Reviews
42
Ranking in other categories
Anti-Malware Tools (14th)
 

Mindshare comparison

As of November 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 3.0%, down from 4.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Exchange Online Protection (EOP)3.0%
Cisco Secure Email Threat Defense1.1%
Other95.9%
Email Security
 

Featured Reviews

GC
Senior Cybersecurity Engineer at a financial services firm with 11-50 employees
Provides robust email security features but requires improved modernization and complexity management
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilities. The initial setup is not straightforward and requires expertise and time to master configurations such as spoofing and DLP. More control over backend functionalities and simplifying rule management could enhance user experience. The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration. Furthermore, the pricing might deter new users who could opt for alternative, more cost-effective solutions.
NancyHartman - PeerSpot reviewer
Business Process Manager/ Educational Technologist at a educational organization with 1,001-5,000 employees
Layered email security has protected sensitive research and still flags phishing in real time
The valuable features of Microsoft Exchange Online Protection (EOP) include providing an additional layer of protection, as it builds on the basic Exchange level of security that allows us to get our work done. Another feature I appreciate is the ability to question things, as our Exchange server allows us to identify in real-time if an email is a phishing email or spam email. It really helps us identify risks, especially through our external exchanges via email or through our cloud-based platforms. Our Exchange system blocks any embedded AI from all our applications and products, so we cannot use embedded AI in our daily work from our official laptops because we have secure information. The system is quite locked down.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Secure Email Threat Defense's scalability is good."
"The product offers protection, email security, anti-spam, and antivirus."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Currently, the ease of deployment is the low-hanging fruit for Cisco email security."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The advanced threat analytics and URL filtering in threat detection are good features that are working well."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"The pre-set policies and configuration analyzer are the most valuable features."
"The email policy configuration options in Microsoft EOP are satisfactory."
"It is easy to configure, easy to use, easy to add exclusions, easy to track, and easy to add anything else if you want."
"The threat management feature includes policies and alerts that are valuable."
"The most valuable feature of Microsoft Exchange Online Protection is the accidental release of information protection capabilities, and additionally, the solution is easy to use."
"The initial setup is just a standard process."
"In general, my company is happy with Microsoft support...My company hasn't faced any stability issues with the solution."
"The product's most valuable feature is third-party integrations."
 

Cons

"The pricing could always be better."
"The search area has room for improvement."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"This solution could be improved by integration with Sandbox."
"We encounter issues while searching for missing emails."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"The physical appliance has been discontinued, although the platform still exists."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"The licensing can be on the expensive side, especially in the cloud space."
"The user interface of Microsoft Exchange Online Protection (EOP) has room for improvement, as at times it doesn't make sense where to go to access certain features."
"It wasn't easy or intuitive enough for me to start using it. So, the reason was that the solution changed."
"The product could be more stable. Microsoft products could be more stable because sometimes, even though they are updating some things, we cannot find those updates."
"The biggest issue that I experience is that Microsoft keeps moving things around, and it's very inconsistent as to where you find the information when you're trying to work on different pieces."
"We would like the solution to have more in-built intelligence in the way that it reviews potential security risks, rather than our team constantly having to update the policies."
"The solution must improve the user experience."
"I am somewhat happy with technical support from Microsoft. Sometimes it takes a while to get through to the right person or team."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution's pricing is subscription-based rather than a yearly licensing cost. Pricing is based on the size of the environment and company and can be expensive."
"The pricing of the solution is reasonable."
"The price of Microsoft Exchange Online Protection is reasonable."
"The product's pricing is competitive for the US market."
"The product is expensive."
"The tool's pricing is excellent."
"Microsoft Exchange Online Protection is a good solution at an affordable price. It is a good investment."
"Regarding the price, it's comparable to other service providers. We've also looked at Check Point's offerings, and the pricing doesn't seem to be an issue."
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Top Industries

By visitors reading reviews
Marketing Services Firm
11%
Outsourcing Company
9%
Healthcare Company
9%
Comms Service Provider
9%
Financial Services Firm
12%
Comms Service Provider
9%
Manufacturing Company
9%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise6
Large Enterprise13
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What needs improvement with Microsoft Exchange Online Protection?
From an end-user point of view, I am quite happy with Microsoft Exchange Online Protection (EOP) because my favorite feature is the ease with which I can identify if an email is a phishing email or...
What is your primary use case for Microsoft Exchange Online Protection?
Microsoft Exchange Online Protection (EOP) serves as the main use case for my company because, as a research company, we require a very high level of security. We use multiple authentication method...
What advice do you have for others considering Microsoft Exchange Online Protection?
My experience with Microsoft Exchange Online Protection (EOP) is from an end-user perspective, and I do not have admin management experience. I am not familiar with the Advanced Threat Protection f...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: November 2026.
920,336 professionals have used our research since 2012.