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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
48
Ranking in other categories
Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
4th
Average Rating
8.2
Reviews Sentiment
6.9
Number of Reviews
36
Ranking in other categories
Anti-Malware Tools (8th)
 

Mindshare comparison

As of March 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 13.5%, down from 19.7% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.0%, down from 1.2% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 7.1%, down from 9.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
Nur Mohammad - PeerSpot reviewer
An effective email security solution that provides DLP, Safe Attachment, and Safe Links
If you want extensive email security, you need to purchase a Plan 2 license. Plan 1 and Plan 2 are the two plans for Microsoft Exchange Online Protection. Some customers hesitate to purchase this product because it adds some costs to them, which is necessary for them. It would be helpful for customers if Plan 1 features were included with EOP. However, they still need to purchase Plan 2 for advanced security features. One of our clients recently requested to compare Zimbra's features with Microsoft Exchange Online Protection. Zimbra is open source, while Microsoft Exchange Online Protection is not. When I compare both the products, many free features are available in Zimbra because it is open-source software. It makes no sense to request Microsoft Exchange Online Protection add all the features people get on open-source software like Zimbra. Hence, I would say whatever features Microsoft Exchange Online Protection has are enough. Microsoft has a dedicated research team that should research and add new techniques like phishing and spamming solutions to the product.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"It gives us visibility into threats and, for endpoints, it helps us to prioritize threats. We used to have a lack of visibility, but now our time to detect and respond has decreased."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"Our customers are satisfied with Defender for 365 because Microsoft products are easy to use and customize to meet the client's needs. Everything is in one place, so we can adjust policies as needed for phishing, DLP, ATP, or any other security features that our clients want to apply."
"The most valuable feature of Microsoft Defender for Office 365 is data backups that we can provide through ticket requests."
"We use Microsoft Defender for its ability to integrate with existing business technologies, which is beneficial for protecting business areas."
"It’s easy to handle integrations, and we don't need a lot of people in our IT team."
"Since we have started using the solution, there have been fewer compromises."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"It has an efficient email filtering feature."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"Secure Email Threat Defense's scalability is good."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"This solution is easy to use."
"I highly recommend it as one of the best choices."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The most valuable feature is the ease of administration. Other solutions require complex administration, but Microsoft Exchange Online Protection is easier."
"It is an easy solution."
"The email policy configuration options in Microsoft EOP are satisfactory."
"You can use the product to create special accounts."
"The security features provided by Microsoft are robust."
"The most valuable feature of Microsoft Exchange Online Protection is the accidental release of information protection capabilities. Additionally, the solution is easy to use."
"The product protects against malware."
"The initial setup of Microsoft Exchange Online Protection was easy."
 

Cons

"We need to be able to whitelist data at the backend."
"Microsoft Defender for Office 365 must improve the overall management style, including the GUI. It also needs to change the filters so that it is easy to whitelist and blacklist data."
"Configuring the default strategies and policies in Microsoft Defender for Cloud Apps generates a lot of noise and false positives."
"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"The XDR dashboard has room for improvement."
"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"The pre-sales cost calculations could be more transparent."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The physical appliance has been discontinued, although the platform still exists."
"We encounter issues while searching for missing emails."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The solution is a bit expensive."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"Microsoft 365 Defender and EOP policies are stable with the proper license. However, with the basic policy, it's hard to say it's stable due to configuration limitations."
"Online Protection has an issue in that it doesn't provide an option to stop impersonation."
"I would like to get reports about vulnerable connections from our clients with information about domains, public IPs, etc. That would be highly useful."
"The product's end-of-life cycle could be extended."
"If a company wants to put in line back-to-back anti-spam solutions, they need to work on that part because Microsoft recommends either you use EOP as a front line or you don't use it."
"Some of the searchability when looking for specifics in Exchange logs is tedious."
"The solution needs to improve its backup."
"The tool's classification for bulk email is cumbersome."
 

Pricing and Cost Advice

"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The pricing is normal. Considering its popularity, it's not overpriced."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"The price could be lower."
"The product is expensive."
"The pricing for the solution depends on what you are trying to achieve with the use of the product, but I know that it is not a cheaply priced product. Yearly payments have to be made towards the licensing fees of the solution."
"The pricing of the solution is reasonable."
"Apart from the license fee for the solution, there are no additional costs."
"Online Protection is fairly expensive."
"The product's pricing is competitive for the US market."
"On a scale of one to ten, where one is cheap, and ten is very expensive, I rate the pricing a six. For licensing, we can make monthly or yearly payments. Right now, we pay 5 USD per month to secure a person's license."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
37%
Healthcare Company
7%
Manufacturing Company
6%
Comms Service Provider
6%
Computer Software Company
15%
Financial Services Firm
9%
Government
9%
Manufacturing Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
I don't have detailed specifics on pricing, setup cost, or licensing.
What needs improvement with Microsoft Defender for Office 365?
I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost.
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
Some of the searchability when looking for specifics in Exchange logs is tedious. Although eventually the information...
What is your primary use case for Microsoft Exchange Online Protection?
I use the tools to protect customers' emails, mostly utilizing Defender products to protect emails and links from Sha...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: March 2025.
842,651 professionals have used our research since 2012.