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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (12th), Data Loss Prevention (DLP) (21st), Cloud Access Security Brokers (CASB) (13th), Distributed Denial-of-Service (DDoS) Protection (8th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email Threat D...
Ranking in Email Security
19th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
8th
Average Rating
8.2
Reviews Sentiment
6.6
Number of Reviews
42
Ranking in other categories
Anti-Malware Tools (13th)
 

Mindshare comparison

As of June 2026, in the Email Security category, the mindshare of Cloudflare One is 1.6%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.1% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 3.3%, down from 6.6% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Exchange Online Protection (EOP)3.3%
Cisco Secure Email Threat Defense1.1%
Cloudflare One1.6%
Other94.0%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
reviewer2541525 - PeerSpot reviewer
Principal Cyber Prevent and Defense Engineer at a comms service provider with 1,001-5,000 employees
Clawback feature performs well but analytics and integration capabilities need improvement
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty in sending logs to our SIEM. Cisco Secure Email Threat Defense's flexibility could be enhanced while it mostly integrates with cloud solutions, but not on-premise. The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious. Regarding room for improvement, the significant number of false positives should be addressed. The solution does not adapt to behavioral analytics and does not make changes when it sees a pattern.
NancyHartman - PeerSpot reviewer
Business Process Manager/ Educational Technologist at a educational organization with 1,001-5,000 employees
Layered email security has protected sensitive research and still flags phishing in real time
The valuable features of Microsoft Exchange Online Protection (EOP) include providing an additional layer of protection, as it builds on the basic Exchange level of security that allows us to get our work done. Another feature I appreciate is the ability to question things, as our Exchange server allows us to identify in real-time if an email is a phishing email or spam email. It really helps us identify risks, especially through our external exchanges via email or through our cloud-based platforms. Our Exchange system blocks any embedded AI from all our applications and products, so we cannot use embedded AI in our daily work from our official laptops because we have secure information. The system is quite locked down.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The blocking feature is very good."
"Cloudflare Access is part of the Zero Trust philosophy."
"The capabilities of the software are strong enough for me to do what it's supposed to do. For me, we don't need to do a lot of configuration on our site. We just enable it and monitor it."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"We mostly use Cloudflare WAF, and gets basic Cloudflaire DDoS, caching as extra bonus . We like the factor these features are all integrated into 1 console, simple to manage."
"Cloudflare is simple to use."
"Cloudflare, in my opinion, was easy to implement."
"Cloudflare is by far the most effective solution that I have come across."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"It's very easy to deploy and configure."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"Cisco Secure Email Threat Defense's best features include user management of graymail, enhancing security awareness by allowing users to manage cold calls, sales-based items, and ensuring email compliance."
"Cisco Cloud Mailbox is used for copying emails, anti-spamming, and securing the company's email, and we really enjoy the anti-spamming capabilities as well as the rejecting of bulk emails, which we can customize by adjusting the variables, and it is very user-friendly."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"The features and functionalities are much better than Microsoft's in-built Defender plan, and this product has helped us to protect our organization from any malware attack in the past."
"The solution uses artificial intelligence and machine learning, so you don't need train it to detect something. The detection and response times are short. It's an excellent product."
"Microsoft Exchange Online Protection (EOP) is used essentially for email filtering, acting as an anti-spam and security product for email."
"The product's most valuable feature is third-party integrations."
"It's definitely scalable."
"The initial setup is just a standard process."
"It is useful for local users and our company because we use Microsoft 365."
"The threat management feature includes policies and alerts that are valuable."
"We like the holding facility that is available for potentially suspicious URLs, which allows a real-time review to be performed before the email reaches a user's inbox."
 

Cons

"The tool should provide on-premise versions. Currently, all versions are cloud-based."
"From a logging perspective, it is still a bit difficult to see exactly what users are being blocked with the current views."
"The pricing is an area that can be improved. Pricing, as far as I recall, was the source of our problems."
"Cloudflare DDoS has poor technical support."
"Our customers no longer use Cloudflare because its service is subpar."
"When there are any dynamic changes in complex applications, the tool takes a lot of time, making its analytics-related area a major matter of concern where improvements are needed."
"I would like them to include a VPN feature to provide a secure connection to the data center."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned."
"The physical appliance has been discontinued, although the platform still exists."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"I wouldn't recommend Cisco to others because I think Fortinet is better."
"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting."
"This solution could be improved by integration with Sandbox."
"The search area has room for improvement."
"Online Protection has an issue in that it doesn't provide an option to stop impersonation."
"It wasn't easy or intuitive enough for me to start using it. So, the reason was that the solution changed."
"The price could be lower."
"We would like the solution to have more in-built intelligence in the way that it reviews potential security risks, rather than our team constantly having to update the policies."
"The price of Microsoft Exchange Online Protection could be reduced to make it more competitive."
"It kind of has a heavy footprint in terms of an implementation footprint."
"Having orchestration features added to Microsoft Exchange Online Protection, particularly automation and remediation, would be quite useful."
"The product's end-of-life cycle could be extended."
 

Pricing and Cost Advice

"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The prices are slightly expensive."
"The solution's pricing lacks transparency."
"The solution is not that expensive."
"Cloudflare Zero Trust Platform's pricing is good."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"The product's pricing is competitive for the US market."
"The solution is expensive but is backed by Microsoft's reputation."
"The product is expensive."
"Online Protection is fairly expensive."
"The tool's pricing is excellent."
"The pricing of the solution is reasonable."
"On a scale of one to ten, where one is cheap, and ten is very expensive, I rate the pricing a six. For licensing, we can make monthly or yearly payments. Right now, we pay 5 USD per month to secure a person's license."
"The product is bundled with Microsoft 365."
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Top Industries

By visitors reading reviews
Construction Company
19%
Comms Service Provider
10%
Financial Services Firm
9%
Manufacturing Company
8%
Marketing Services Firm
12%
Manufacturing Company
8%
Computer Software Company
7%
Government
7%
Financial Services Firm
12%
Manufacturing Company
9%
Computer Software Company
9%
Government
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise1
Large Enterprise12
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise7
Large Enterprise11
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, ...
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new ...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat De...
What needs improvement with Microsoft Exchange Online Protection?
From an end-user point of view, I am quite happy with Microsoft Exchange Online Protection (EOP) because my favorite ...
What is your primary use case for Microsoft Exchange Online Protection?
Microsoft Exchange Online Protection (EOP) serves as the main use case for my company because, as a research company,...
What advice do you have for others considering Microsoft Exchange Online Protection?
My experience with Microsoft Exchange Online Protection (EOP) is from an end-user perspective, and I do not have admi...
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

23andMe
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: June 2026.
899,125 professionals have used our research since 2012.