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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
23rd
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
9th
Average Rating
8.2
Reviews Sentiment
6.6
Number of Reviews
42
Ranking in other categories
Anti-Malware Tools (14th)
 

Mindshare comparison

As of September 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 2.9%, down from 5.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Exchange Online Protection (EOP)2.9%
Cisco Secure Email Threat Defense1.1%
Other96.0%
Email Security
 

Featured Reviews

NM
Enginner at Millennium Information Technologies
Has faced challenges with configuration, taking actions, and learning curve but benefits from centralized management and good technical support
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, are limited as ETD only supports sending audit logs. Customers have requirements for other system logs as well, which should be developed from their side. Another customer request is to restrict the IPs that can log in, which cannot be done from Cisco Secure Email Threat Defense yet. Any user with login details can log in. We can restrict the IPs in Cloud Mail Gateways, but not from Cisco Secure Email Threat Defense. It would be beneficial to improve this feature. Cisco Secure Email Threat Defense can take actions, such as requesting O365 to quarantine mail. In that case, the customer requires notification to the recipient from Cisco Secure Email Threat Defense. This option would be valuable if available. The real-time threat intelligence of Cisco Secure Email Threat Defense is an AI-based classification. It took one to two months to optimize the classification, but we still experience some false positives. Reducing the learning period would be beneficial. The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned. Reducing the learning time would be much better. Additional features desired in the next release include IP restrictions and user logging IP restrictions, ensuring only the customer environment can log in to Cisco Secure Email Threat Defense. Logs forwarding needs improvement as currently it only has audit logs. In Cloud Mail Gateway, we can create an IPsec tunnel to forward logs. However, in Cisco Secure Email Threat Defense, there is no option, and we must do API integration to send logs. Only SIM can get logs; Syslog cannot retrieve them.
NancyHartman - PeerSpot reviewer
Business Process Manager/ Educational Technologist at a educational organization with 1,001-5,000 employees
Layered email security has protected sensitive research and still flags phishing in real time
The valuable features of Microsoft Exchange Online Protection (EOP) include providing an additional layer of protection, as it builds on the basic Exchange level of security that allows us to get our work done. Another feature I appreciate is the ability to question things, as our Exchange server allows us to identify in real-time if an email is a phishing email or spam email. It really helps us identify risks, especially through our external exchanges via email or through our cloud-based platforms. Our Exchange system blocks any embedded AI from all our applications and products, so we cannot use embedded AI in our daily work from our official laptops because we have secure information. The system is quite locked down.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"This solution is easy to use."
"I highly recommend it as one of the best choices."
"On ease of use, it rates very high."
"Overall, it's certainly a very good idea to integrate another layer on top of Microsoft Advanced Threat Protection."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"Currently, the ease of deployment is the low-hanging fruit for Cisco email security."
"The solution is stable."
"Microsoft Exchange Online Protection has features like DLP (data loss protection), Safe Attachment, and Safe Links."
"The email policy configuration options in Microsoft EOP are satisfactory."
"The most valuable features of Microsoft Exchange Online Protection are the EOP, ATP, safe links, fishing, and antispam."
"It is easy to configure, easy to use, easy to add exclusions, easy to track, and easy to add anything else if you want."
"It provides security to both on-premises and Azure infrastructures."
"We like the holding facility that is available for potentially suspicious URLs, which allows a real-time review to be performed before the email reaches a user's inbox."
"It's all running in the backend, so it doesn't affect the app functionality."
"Microsoft EOP's most valuable feature is a shared mailbox."
 

Cons

"The solution is a bit expensive. It could be cheaper."
"The pricing could always be better."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The physical appliance has been discontinued, although the platform still exists."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"I think the implementation could be more streamlined."
"The solution can be complex at times. It would be nice to have the on-server version. It needs to improve the stability as well."
"Having orchestration features added to Microsoft Exchange Online Protection, particularly automation and remediation, would be quite useful."
"The tool is not 100% stable."
"Microsoft Exchange Online Protection is quite a difficult product."
"Microsoft has some training portals, but more could be developed."
"The price could be lower."
"The security features could be better and more secure in the next release."
 

Pricing and Cost Advice

"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution's pricing is subscription-based rather than a yearly licensing cost. Pricing is based on the size of the environment and company and can be expensive."
"The product is bundled with Microsoft 365."
"The product's pricing is competitive for the US market."
"It's a high price."
"The pricing for the solution depends on what you are trying to achieve with the use of the product, but I know that it is not a cheaply priced product. Yearly payments have to be made towards the licensing fees of the solution."
"On a scale of one to ten, where one is cheap, and ten is very expensive, I rate the pricing a six. For licensing, we can make monthly or yearly payments. Right now, we pay 5 USD per month to secure a person's license."
"The solution should reduce the cost."
"The price of Microsoft Exchange Online Protection is reasonable."
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Top Industries

By visitors reading reviews
Marketing Services Firm
11%
Outsourcing Company
9%
Comms Service Provider
8%
Healthcare Company
8%
Financial Services Firm
11%
Manufacturing Company
9%
Comms Service Provider
8%
Computer Software Company
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise6
Large Enterprise13
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What needs improvement with Microsoft Exchange Online Protection?
From an end-user point of view, I am quite happy with Microsoft Exchange Online Protection (EOP) because my favorite feature is the ease with which I can identify if an email is a phishing email or...
What is your primary use case for Microsoft Exchange Online Protection?
Microsoft Exchange Online Protection (EOP) serves as the main use case for my company because, as a research company, we require a very high level of security. We use multiple authentication method...
What advice do you have for others considering Microsoft Exchange Online Protection?
My experience with Microsoft Exchange Online Protection (EOP) is from an end-user perspective, and I do not have admin management experience. I am not familiar with the Advanced Threat Protection f...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: September 2026.
912,022 professionals have used our research since 2012.