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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

Why PeerSpot?
 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
23rd
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
9th
Average Rating
8.2
Reviews Sentiment
6.6
Number of Reviews
42
Ranking in other categories
Anti-Malware Tools (14th)
 

Mindshare comparison

As of September 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 2.9%, down from 5.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Exchange Online Protection (EOP)2.9%
Cisco Secure Email Threat Defense1.1%
Other96.0%
Email Security
 

Featured Reviews

GC
Senior Cybersecurity Engineer at a financial services firm with 11-50 employees
Provides robust email security features but requires improved modernization and complexity management
Modernization is an area that could be improved for Cisco Secure Email Threat Defense, as some features have lagged behind newer competitors, potentially offering more advanced analysis capabilities. The initial setup is not straightforward and requires expertise and time to master configurations such as spoofing and DLP. More control over backend functionalities and simplifying rule management could enhance user experience. The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration. Furthermore, the pricing might deter new users who could opt for alternative, more cost-effective solutions.
NancyHartman - PeerSpot reviewer
Business Process Manager/ Educational Technologist at a educational organization with 1,001-5,000 employees
Layered email security has protected sensitive research and still flags phishing in real time
The valuable features of Microsoft Exchange Online Protection (EOP) include providing an additional layer of protection, as it builds on the basic Exchange level of security that allows us to get our work done. Another feature I appreciate is the ability to question things, as our Exchange server allows us to identify in real-time if an email is a phishing email or spam email. It really helps us identify risks, especially through our external exchanges via email or through our cloud-based platforms. Our Exchange system blocks any embedded AI from all our applications and products, so we cannot use embedded AI in our daily work from our official laptops because we have secure information. The system is quite locked down.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"It has an efficient email filtering feature."
"This solution is easy to use."
"Currently, the ease of deployment is the low-hanging fruit for Cisco email security."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"Regarding stability, Cisco Secure Email Threat Defense is very stable."
"Cisco Secure Email Threat Defense's best features include user management of graymail, enhancing security awareness by allowing users to manage cold calls, sales-based items, and ensuring email compliance."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The most valuable feature of Microsoft Exchange Online Protection is the accidental release of information protection capabilities, and additionally, the solution is easy to use."
"It provides security to both on-premises and Azure infrastructures."
"The initial setup was easy. The configuration process is very straightforward."
"Overall, I think it's really a great product."
"Microsoft Exchange Online Protection (EOP) is used essentially for email filtering, acting as an anti-spam and security product for email."
"What I like most about Microsoft Exchange Online Protection is its integration with Windows, so we have one central view for all alerts and incidents."
"The solution's stability is very, very good. I didn't face any problems in the last year."
"The email policy configuration options in Microsoft EOP are satisfactory."
 

Cons

"The search area has room for improvement."
"The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious."
"The physical appliance has been discontinued, although the platform still exists."
"The learning curve shows that in the beginning, there are numerous false positives. For one month, we had to reclassify the false positives manually until the system learned."
"The pricing could always be better."
"The solution is a bit expensive. It could be cheaper."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"The biggest issue that I experience is that Microsoft keeps moving things around, and it's very inconsistent as to where you find the information when you're trying to work on different pieces."
"Our company faces difficulty with Microsoft Exchange Online Protection (EOP) because it's too big, clunky, and difficult for a small client to implement quickly and easily."
"The reporting needs a little bit of improvement."
"Besides price, the main room for improvement includes the sandbox or something similar; the usability that solutions are focused on."
"The solution lacks to elaborate on its spam policies."
"Performance and speed should continue to be improved."
"The security features could be better and more secure in the next release."
"The licensing can be on the expensive side, especially in the cloud space."
 

Pricing and Cost Advice

"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The solution’s pricing is manageable."
"The feedback from vendors and customer is that it is expensive."
"It's a high price."
"The pricing for the solution depends on what you are trying to achieve with the use of the product, but I know that it is not a cheaply priced product. Yearly payments have to be made towards the licensing fees of the solution."
"It is a low-price solution."
"Apart from the license fee for the solution, there are no additional costs."
"The tool's pricing is excellent."
"The solution falls on the higher or more expensive side of the spectrum."
"The price could be lower."
"Regarding the price, it's comparable to other service providers. We've also looked at Check Point's offerings, and the pricing doesn't seem to be an issue."
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Top Industries

By visitors reading reviews
Marketing Services Firm
11%
Outsourcing Company
9%
Comms Service Provider
8%
Healthcare Company
8%
Financial Services Firm
11%
Manufacturing Company
9%
Comms Service Provider
9%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business23
Midsize Enterprise6
Large Enterprise13
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What needs improvement with Microsoft Exchange Online Protection?
From an end-user point of view, I am quite happy with Microsoft Exchange Online Protection (EOP) because my favorite feature is the ease with which I can identify if an email is a phishing email or...
What is your primary use case for Microsoft Exchange Online Protection?
Microsoft Exchange Online Protection (EOP) serves as the main use case for my company because, as a research company, we require a very high level of security. We use multiple authentication method...
What advice do you have for others considering Microsoft Exchange Online Protection?
My experience with Microsoft Exchange Online Protection (EOP) is from an end-user perspective, and I do not have admin management experience. I am not familiar with the Advanced Threat Protection f...
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: September 2026.
914,805 professionals have used our research since 2012.