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Cisco Secure Email Threat Defense vs Microsoft Exchange Online Protection (EOP) comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco Secure Email Threat D...
Ranking in Email Security
26th
Average Rating
8.0
Reviews Sentiment
6.7
Number of Reviews
16
Ranking in other categories
No ranking in other categories
Microsoft Exchange Online P...
Ranking in Email Security
7th
Average Rating
8.2
Reviews Sentiment
6.7
Number of Reviews
41
Ranking in other categories
Anti-Malware Tools (12th)
 

Mindshare comparison

As of January 2026, in the Email Security category, the mindshare of Cisco Secure Email Threat Defense is 1.1%, up from 1.0% compared to the previous year. The mindshare of Microsoft Exchange Online Protection (EOP) is 4.4%, down from 7.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Market Share Distribution
ProductMarket Share (%)
Microsoft Exchange Online Protection (EOP)4.4%
Cisco Secure Email Threat Defense1.1%
Other94.5%
Email Security
 

Featured Reviews

reviewer2541525 - PeerSpot reviewer
Principal Cyber Prevent and Defense Engineer at a comms service provider with 1,001-5,000 employees
Clawback feature performs well but analytics and integration capabilities need improvement
The integration capability with other threat intelligence platforms is not optimal, as I have experienced difficulty in sending logs to our SIEM. Cisco Secure Email Threat Defense's flexibility could be enhanced while it mostly integrates with cloud solutions, but not on-premise. The behavioral analysis capability of Cisco Secure Email Threat Defense is not particularly helpful for identifying new, evolving threats within my company, as it keeps flagging legitimate emails as malicious. Regarding room for improvement, the significant number of false positives should be addressed. The solution does not adapt to behavioral analytics and does not make changes when it sees a pattern.
HP
Cloud Consultant at Ensono
Service provider benefits from effective email security management and seeks enhanced customer support
Reporting could be one of the areas for improvement, as they could put more reporting into Microsoft Exchange Online Protection (EOP) natively rather than requiring additional licensing or connecting to other parts of the Microsoft suite, but it depends on the license you have. There aren't significant concerns with Microsoft Exchange Online Protection (EOP), as it depends on what customers expect; if they expect more features, then it depends on what Microsoft 365 license they have. The important thing is to ensure they are using all the security features they get with their licensing. The basic one is Microsoft Exchange Online Protection (EOP). While it's nice to have more functionality, that's available through other licensing programs with Microsoft. While we'd prefer more features, as a basic tool, it's fine, but more advanced features come with the add-ons from other parts of the Microsoft 365 licensing. One feature that could improve Microsoft Exchange Online Protection (EOP) is automated malware detection, where it actually analyzes the file offline in a sandbox to determine if it's safe, potentially reducing false positives.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"This solution is easy to use."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The advanced threat analytics and URL filtering in threat detection are good features that are working well."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"Cisco Secure Email Cloud Mailbox can handle a complete portfolio, which is required to protect any kind of attack coming from emails. However, it does not have advanced phishing, but it is available through Cisco. If you compare Cisco Secure Email Cloud Mailbox with the competition, in the competition you have to have one or two solutions together to address the customer's requirement, whereas Cisco Secure Email Cloud Mailbox is addressing everything, such as web domain and email protection. If there is any kind of challenge it will come across through email."
"I would say it's very comprehensive, with multiple antivirus OEMs, virus encrypt features, encryption, and more."
"The solution is stable."
"It's all running in the backend, so it doesn't affect the app functionality."
"We use the solution in all our environments. We use it for remedy tickets and give them updates. It was our main communication point."
"The initial setup was easy. The configuration process is very straightforward."
"You can use the product to create special accounts."
"It provides security to both on-premises and Azure infrastructures."
"The threat management feature includes policies and alerts that are valuable."
"We use the solution to receive emails. We do not use the calendar function as our clients are slow adaptors to the latest features."
"The initial setup is just a standard process."
 

Cons

"The pricing could always be better."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The product's complexity at times results in redundant rule sets that are difficult to untangle, highlighting the need for streamlined management systems and a more user-centric approach to system configuration."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The physical appliance has been discontinued, although the platform still exists."
"I think the implementation could be more streamlined."
"When you're using a Microsoft product solution, you can scale it, but if you're not, there are limitations."
"The solution lacks to elaborate on its spam policies."
"Our company faces difficulty with Microsoft Exchange Online Protection (EOP) because it's too big, clunky, and difficult for a small client to implement quickly and easily."
"Not all settings can be configured automatically and most still require manual configuration. However, there is an automation tool available that can be used to input all the configurations either as a script or a tool it would be helpful."
"Online Protection has an issue in that it doesn't provide an option to stop impersonation."
"The licensing can be on the expensive side, especially in the cloud space."
"It wasn't easy or intuitive enough for me to start using it. So, the reason was that the solution changed."
 

Pricing and Cost Advice

"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The product's pricing is competitive for the US market."
"The solution falls on the higher or more expensive side of the spectrum."
"The product is bundled with Microsoft 365."
"It's a high price."
"The price of Microsoft Exchange Online Protection is reasonable."
"The tool's pricing is excellent."
"Online Protection is fairly expensive."
"Microsoft Exchange Online Protection's pricing is a little bit more because its price has recently increased."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Manufacturing Company
8%
Marketing Services Firm
8%
Healthcare Company
7%
Computer Software Company
13%
Financial Services Firm
10%
Manufacturing Company
8%
Government
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise6
Large Enterprise7
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise7
Large Enterprise10
 

Questions from the Community

What is your experience regarding pricing and costs for Secure Email Threat Defense?
Comparatively with other products, the pricing of Cisco Secure Email Threat Defense is normal. As a technical guide, I am not very aware of the pricing details.
What needs improvement with Secure Email Threat Defense?
We have deployed Cisco Secure Email Threat Defense in two customer environments. It is still in development as a new product. Some customer requirements, such as sending logs to a Syslog server, ar...
What is your primary use case for Secure Email Threat Defense?
We are working with Cloud Mail Gateway and on-premise mail gateways. We have worked with Cisco Secure Email Threat Defense.
What do you like most about Microsoft Exchange Online Protection?
The initial setup was easy. The configuration process is very straightforward.
What needs improvement with Microsoft Exchange Online Protection?
The user interface of Microsoft Exchange Online Protection (EOP) has room for improvement, as at times it doesn't make sense where to go to access certain features.
What is your primary use case for Microsoft Exchange Online Protection?
My use case for Microsoft Exchange Online Protection (EOP) is basically to protect ourselves from phishing emails and to improve our email security.
 

Also Known As

Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Microsoft EOP, MS Exchange Online Protection
 

Overview

 

Sample Customers

Luiss University, Lone Star College, T-Systems, Magyar Telekom
Information Not Available
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Microsoft Exchange Online Protection (EOP) and other solutions. Updated: December 2025.
879,986 professionals have used our research since 2012.