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Cisco SecureX [EOL] vs Microsoft Defender XDR comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cisco SecureX [EOL]
Average Rating
9.0
Reviews Sentiment
8.2
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Microsoft Defender XDR
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
106
Ranking in other categories
Endpoint Detection and Response (EDR) (7th), Extended Detection and Response (XDR) (3rd), Microsoft Security Suite (5th)
 

Featured Reviews

Dene Lewis - PeerSpot reviewer
Head of Technical Strategy and Direction CAE Technology Services Ltd at CAE Technology Services Limited
A scalable SaaS based platform that helps with cyber threat intelligence and automated hunting
I would rate Cisco SecureX a ten out of ten. I find the product to be a fantastic platform. If you are eligible, start using it straight away. The best way to evaluate it is to start using it and see where it fits within your organization. I think it helps our customers really deliver their SecOps goals, and I see it as a core foundation of CAE's own security strategy going forward. Our partnership with Cisco is one that was built on trust over a long period of time. This has enabled us to work together to be able to provide the solutions that our customers need to drive their organizations forward. The value we add as a reseller is being able to work closer with our customers, understand them, and get intimate with their organizations. That enables us to offer them the right solutions that will help them achieve their goals.
KO
House security operator at Cypress Creek Renewables
Advanced threat hunting saves significant time in tracking and responding to incidents
Microsoft Defender XDR could be improved with a lower price. My main suggestion would essentially be what Copilot is providing, which is a single pane of glass, so I don't have to go to different windows. That's just a workflow consideration for me. It would be great to have all the information centralized into one particular data app. If I need to open up extra ones, I can, however, I would appreciate a future where everything I need is right there on one single pane of glass. Beyond that, there's really nothing else I see that I would want Microsoft to improve.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The ability to create firewalls online has been most valuable including the ability to create rules."
"The automation and orchestration tools are the most valuable features."
"Using SecureX, a tool provided by Cisco, we can easily integrate it with many of our other Cisco products such as Cisco ISE and many networking devices."
"SecureX takes all the separate pieces of security within your company, adds in intelligence from different sites and services on the internet, and makes them work together."
"SecureX enables us to have all the threat intelligence and threat event data in one place."
"Integrates well with our existing security infrastructure."
"It has evolved a lot, just that monitoring piece to the current Orchestrator piece. The additional analytics are there. They now have something called Insight, which can basically take data from Microsoft Azure AD and Intune to give us information about our endpoints. This is detailed information about the endpoints, from Secure Endpoint and all these different products. So, it is just constantly evolving. Every time that it evolves, we have more information with more visibility. There are more features that we have that just make everything so much easier, and it is in one place. I don't have to keep going back and forth. I don't have to go to Secure Endpoint and ISE to get the data. I don't have to go to Intune on Microsoft to get the information. It is all in one place."
"The most beneficial feature of Cisco SecureX for cybersecurity efforts is its integration with other Cisco solutions and the environment. This sets it apart, as its APIs and overall integration capabilities are very strong. Additionally, its detection capabilities are commendable."
"I like that it's fully integrated with Windows, Microsoft 365 Exchange Online, and Outlook. It is better than other antivirus solutions because it's fully integrated with all Microsoft products. It's easy to integrate them and onboard all Windows devices from SCCM."
"It provides a single pane of glass within the 365 admin interface, streamlining our experience by consolidating information in one place and eliminating the need to navigate through multiple interfaces."
"In our company,we have faced multiple attacks over the last few months, but none of them have been successful, and I think Microsoft Defender XDR has played a major role in it."
"Advanced hunting is good. I like that. We can drill down to lots of details."
"The feature I like the most in Microsoft Defender XDR is XDR because it has taken us a while, but we are a global company with people in a few countries, and now we can have centralized alerts that we send out to Teams messages and clean up infected computers or help people in a very short amount of time."
"I like that it's stable. It's been stable for a long time, and Microsoft Defender has done a good job there."
"Vulnerability assessment and just-in-time access are some valuable features of Defender for server plans."
"Microsoft XDR's system of analysis and investigation is super convenient for our customers. It integrates with other Microsoft solutions like Defender for 365 to protect email traffic from malicious external web links and phishing."
 

Cons

"Remediation stuff could be integrated into the product's automation."
"I would like it to integrate with another solution, e.g., DNA. I would like it to connect to that solution, but not the security aspect."
"If they could make the Cisco Umbrella piece a little bit more advanced or easier to manage, that would help. We use it for filtering and when you compare it to a normal content filter, it lacks some functionality."
"They could put in more third-party [integrations]... also more playbooks, out-of-the-box, for automation [would be helpful]."
"For us, the biggest sticking point is that the product is not being designed for multi-tenancy use at present, from an MSP perspective."
"The documentation can be improved and the on-prem integration. The set of applications that it was integrated with wasn't comprehensive."
"I'm not sure that I would call it a bug, but sometimes the solution is a little slow."
"The automation and orchestration could be simpler. It could be that all the other parts are that easy to use so that these stick out as a negative, but that's the trickiest part for us. The workflows within the orchestration are just a bit more difficult."
"There is definitely scope for improvement in the automation area. Because the solution is a SaaS platform, we don't have the overall ability to automate stuff.... There is no direct way to go ahead because it's a SaaS platform."
"The support team is not competent or responsive."
"Microsoft support is not very good. You get stuck in low-level support for way longer than you should, instead of them escalating the issue up the chain."
"Defender's AI for identifying suspicious activity could be improved. Also, I do a lot of home updates. Maybe there is a way to set it up faster. For example, let's say that I want to automatically update seven computers, servers, etc. I wouldn't do it to a user, but maybe the server. I don't mind if the server restarts automatically."
"For some scenarios, it provides good visibility into threats, and for some scenarios, it doesn't. For example, sometimes the URLs within the emails have destinations, and you do get a screenshot and all further details, but it's not always the case. It would be good if they did a better job of enabling that for all the emails that they identified as malicious. When you get an email threat, you can go into the email and see more details, but the URL destination feature doesn't always show you a screenshot of the URL in that email. It also doesn't always give you the characteristics relating to that URL. It would be quite good if the information is complete where it says that we identified this URL, and this is what it looks like. There should be some threat intel about it. It should give you more details."
"There should be better information for experts on features in the solution. What I see when reading about features in Microsoft 365 Defender is that it is always general information. If Microsoft could go deeper into details for the experts about how to use the tools, usage of it would be more familiar and it would be easier to use."
"Microsoft 365 Defender does not have a unique package with emerging endpoint security technologies, such as EDR and XDR."
"One of the biggest downsides of Microsoft products, in general, is that the menus are often difficult to find, as they tend to move from place to place between versions."
 

Pricing and Cost Advice

"It comes free with all Cisco products. So, it is a good price."
"Cisco SecureX is more expensive than Trend Micro. However, considering the integration capabilities with other solutions and the quality of technical support, I believe there's justification for the price difference."
"The pricing is the best part of this solution. It is free if you buy Umbrella or Duo Security. It is also a good solution."
"It would be nice if they had a different pricing model. Most of our budget for projects goes towards Cisco."
"The product is absolutely free to any customer. As such, the only thing one must keep in mind is that as long as he already has one Cisco security product, irregardless of what that product is, SecureX is available for free."
"It is free. It can't get any better than that."
"The pricing is competitive, especially for education institutions. Licensing can be a little bit difficult to navigate, especially with resellers with Cisco, but for us it has been pretty easy."
"You can spend less money for another solution, but if you really want to have a good solution you have to pay. We are happy that we are getting such a good solution for what we are spending."
"The solutions price is fair for what they offer."
"I would like to have more security features in the lower licenses because not every customer is able to buy E5 licenses. The bundling isn't always easy for our customers to understand. Compared to other tools, it's a good price."
"Understanding the subscription model has been a bit challenging, as every feature or requirement comes with an additional cost."
"365 Defender can get expensive because you pay per gigabyte of data ingested. On the other hand, much of the data available in the other Microsoft security solutions are made available relatively cheaply—sometimes at cost or for free. Integrating only a limited set of third-party solutions with Sentinel would be cost-effective. It's much more affordable if companies only have Microsoft stuff."
"It has consistently offered highly appealing academic pricing, with distinct rates for higher education and general educational purposes."
"The solution is too expensive."
"Defender plan 1 is tenant-wise, and Defender plan 2 is per-user, which makes it more expensive. To have certain features, you would need to purchase the E5 license. For all of the capabilities that the tool provides, the price, though it can be high, is fair."
"While the standalone price of Defender XDR might seem high, its value becomes clear when considering the ease of implementation and smooth integration with our existing Microsoft infrastructure, especially when bundled with other Microsoft products."
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Top Industries

By visitors reading reviews
Computer Software Company
21%
Manufacturing Company
7%
Government
7%
Comms Service Provider
7%
Computer Software Company
13%
Financial Services Firm
9%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business4
Midsize Enterprise7
Large Enterprise3
By reviewers
Company SizeCount
Small Business47
Midsize Enterprise25
Large Enterprise38
 

Questions from the Community

Ask a question
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What do you like most about Microsoft 365 Defender?
Microsoft Defender XDR provides strong identity protection with comprehensive insights into risky user behavior and potential indicators of compromise.
What is your experience regarding pricing and costs for Microsoft 365 Defender?
My experience with pricing, setup, costs, and licensing of Microsoft Defender XDR is tied to our E5 subscription, which is very straightforward for us. We also purchase the uplift for our mobile us...
What needs improvement with Microsoft 365 Defender?
I am not aware of a mobile app that would be available for my team. With a single analyst, if she is ever away, it would be beneficial to have easier access. While she can use the web portal, the e...
 

Also Known As

Kenna.AppSec, Kenna.VI
Microsoft 365 Defender, Microsoft Threat Protection, MS 365 Defender
 

Overview

 

Sample Customers

NHS, Rackspace, UNC Pembroke, University of North Carolina at Charlotte, Missing Piece
Accenture, Deloitte, ExxonMobil, General Electric, IBM, Johnson & Johnson and many others.
Find out what your peers are saying about CrowdStrike, Trend Micro, Microsoft and others in Extended Detection and Response (XDR). Updated: January 2026.
881,176 professionals have used our research since 2012.