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Microsoft Defender for Office 365 vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
48
Ranking in other categories
Email Security (1st), Microsoft Security Suite (11th)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
6.6
Number of Reviews
8
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of April 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 9.2%, down from 15.0% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.7%, up from 1.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
HS
Easy to set up and use with a nice interface
The scalability could be better. We'd like them to be better at dealing with script threats. In sandboxing, the time to respond is slower than we would like. We'd like them to be able to process faster. For example, Fortinet, they are doing 18,000 files per hour. For Wildfire, it is elastic. It can support as many files as you get. McAfee doesn't react like that. It does not support interfaces with HTTPS.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The risk level notifications are most valuable. We get to know what kind of intrusion or attack is there, and we can fix a problem on time."
"The basic features are okay and I'm satisfied with the Defender."
"It’s easy to handle integrations, and we don't need a lot of people in our IT team."
"The most valuable aspect of Microsoft Defender for Office 365 is its ability to protect us from malware."
"The two main features that prove most beneficial for us are URL scanning and attachment scanning."
"Since we have started using the solution, there have been fewer compromises."
"The stability of Microsoft Defender for Office 365 is fantastic."
"Defender for Office 365 has helped eliminate having to look at multiple dashboards and that is the aspect I like most about it. It is simpler, effective, and convenient. The users like the process efficiency."
"It is stable and reliable."
"It is very scalable."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"Provides good exfiltration, and is an all-in-one product."
"I recommend this solution because of its ease of use."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"The most valuable features are the administration console and its detection and response module."
 

Cons

"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"Microsoft Defender for Office 365's Mac functionality requires improvement to deliver the same level of protection found on Windows devices."
"The only thing they should improve is the licensing model. They should stop changing it. A year ago, the five features I mentioned were included in one product. Now, three of them are bundled into one product, and you have to pay extra for the other two. I don't mind paying extra, but I don't want them to change it every year or every six months. I need to know what I'm looking at and not worry about it next year."
"The UI needs to be more user-friendly."
"The XDR dashboard has room for improvement."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Several simulation options are available within 365, and the phishing simulation could be better."
"Configuration requires going to a lot of places rather than just accessing one tab."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"Lacks remote capabilities not dependent on the internet."
"We'd like them to be better at dealing with script threats."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"This solution needs to be made "cloud ready"."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
 

Pricing and Cost Advice

"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"The license is expensive because the cost is based on the number of users."
"The product is very expensive."
"I know that the product is incredibly expensive."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Financial Services Firm
17%
Government
15%
Computer Software Company
13%
Manufacturing Company
13%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
I don't have detailed specifics on pricing, setup cost, or licensing.
What needs improvement with Microsoft Defender for Office 365?
I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost.
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client.
What is your primary use case for McAfee Advanced Threat Defense?
We use the solution for client management and security. We used the whole suite for client Firewall, antivirus, and everything provided by Trellix.
 

Also Known As

MS Defender for Office 365
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Advanced Threat Defense and other solutions. Updated: March 2025.
845,406 professionals have used our research since 2012.