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Microsoft Defender for Office 365 vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
49
Ranking in other categories
Email Security (1st), Microsoft Security Suite (11th)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
6.6
Number of Reviews
8
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of April 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 9.2%, down from 15.0% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.7%, up from 1.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
HS
Easy to set up and use with a nice interface
The scalability could be better. We'd like them to be better at dealing with script threats. In sandboxing, the time to respond is slower than we would like. We'd like them to be able to process faster. For example, Fortinet, they are doing 18,000 files per hour. For Wildfire, it is elastic. It can support as many files as you get. McAfee doesn't react like that. It does not support interfaces with HTTPS.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"Does a thorough job of examining email and URLs for malicious content."
"The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance."
"Scalability-wise, I do not think there are any issues so far."
"The most valuable feature of Microsoft Defender for Office 365 is the ease of use."
"The basic features are okay and I'm satisfied with the Defender."
"Overall, I would rate Microsoft Defender for Office 365 at a ten."
"I would say that 90% of the spam and phishing attack emails get blocked right off the bat."
"Provides good exfiltration, and is an all-in-one product."
"The most valuable features are the administration console and its detection and response module."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"It is very scalable."
"It is stable and reliable."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"I recommend this solution because of its ease of use."
 

Cons

"Microsoft should provide more documentation for users so they can self-educate. I would like to see more documentation for advanced security features."
"The changes to customer service, specifically the new model for support agreements, are not favorable."
"There's room for improvement regarding the time frame for retrieving emails."
"The visibility into threats is not up to the mark, as I do not have control. I rate my experience with Microsoft Defender for Office 365 as six out of ten due to troubleshooting and pricing concerns."
"It would be better if it were more scalable. It depends on the architecture, but we would like to make it more scalable for both data centers."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"Several simulation options are available within 365, and the phishing simulation could be better."
"You should be able to deploy Defender for every subscription without the need to add servers."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
"This solution needs to be made "cloud ready"."
"Lacks remote capabilities not dependent on the internet."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"We'd like them to be better at dealing with script threats."
 

Pricing and Cost Advice

"The pricing is normal. Considering its popularity, it's not overpriced."
"Defender is a little bit more expensive as compared to others. We are in the manufacturing environment. So, we don't have a high budget for all of our endpoint devices. Its cost is a major concern for us."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The license is expensive because the cost is based on the number of users."
"It's a user-base subscription."
"The product is very expensive."
"Microsoft Defender is expensive. I typically recommend it only if clients have the budget. Otherwise, I would suggest an alternative."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Financial Services Firm
18%
Government
15%
Manufacturing Company
14%
Computer Software Company
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Money-wise, it is a part of the Office 365 ( /products/office-365-reviews ) suite, making it slightly more expensive compared to Trend Micro. Although Defender is free, you have to pay separately f...
What needs improvement with Microsoft Defender for Office 365?
The main area for improvement is simplifying the implementation and rollout process. There are many conditions to be met, making it challenging to ensure every system is protected. Troubleshooting ...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client.
What is your primary use case for McAfee Advanced Threat Defense?
We use the solution for client management and security. We used the whole suite for client Firewall, antivirus, and everything provided by Trellix.
 

Also Known As

MS Defender for Office 365
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Advanced Threat Defense and other solutions. Updated: April 2025.
848,989 professionals have used our research since 2012.