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ThreatLocker Zero Trust Endpoint Protection Platform vs Trellix Network Detection and Response comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Mar 23, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
8.1
ThreatLocker Zero Trust Platform enhances security, improves efficiency, saves costs, increases revenue, and supports business growth by reducing threats.
Sentiment score
8.5
Trellix Network Detection and Response exceeded expectations by improving threat prevention and detection, boosting productivity and reducing response times.
If something were to happen without ThreatLocker, the cost would be huge, and thus, having it is definitely worth it.
The main return on investment is peace of mind, knowing that with ThreatLocker on any endpoint, it will almost always block all malicious code or exploits, even zero-day exploits.
It keeps malware, Trojans, and ransomware at bay.
 

Customer Service

Sentiment score
8.8
ThreatLocker Zero Trust's responsive customer service, highlighted by the Cyber Hero program, is praised for speed, professionalism, and effectiveness.
Sentiment score
6.8
Trellix's support is praised for responsiveness, but improvements in expertise and incident response promptness are suggested by some.
They have been very responsive, helpful, and knowledgeable.
I would rate their customer support a ten out of ten.
Their support is world-class.
Technical support needs improvement as sometimes engineers are not available promptly, especially during high-severity incidents.
 

Scalability Issues

Sentiment score
8.2
ThreatLocker Zero Trust Platform offers seamless scalability and adaptability, efficiently managing diverse environments and dynamic growth across endpoints.
Sentiment score
7.8
Trellix Network Detection and Response scales effectively in various industries, performing well in large enterprises without latency issues.
I started off with just the servers, and within a month and a half, I set up the entire company with ThreatLocker.
It seems to primarily operate on the endpoints rather than at a central location pushing out policies.
I would rate it a ten out of ten for scalability.
 

Stability Issues

Sentiment score
7.5
ThreatLocker Zero Trust Platform is praised for stability and reliability, with minor issues swiftly addressed by support.
Sentiment score
7.7
Trellix Network Detection and Response is stable and reliable, with consistent performance and high user satisfaction despite occasional minor issues.
For five years, we have not had a problem.
Once deployed, it downloads the policies locally, so even if the computer doesn't have internet, it doesn't matter.
It has been very stable, reliable, and accessible.
 

Room For Improvement

ThreatLocker needs UI improvements, better integrations, expanded training, enhanced analytics, restricted Learning Mode, and faster support.
Trellix Network Detection needs improved customization, integration, AI capabilities, support services, and a more user-friendly interface at reduced pricing.
Controlling the cloud environment, not just endpoints, is crucial.
This is problematic when immediate attention is needed.
Comprehensive 24-hour log monitoring is a valuable enhancement for both business and enterprise-level users.
There should be improvements in AI intelligence, faster decision-making, and a more responsive technical support team.
 

Setup Cost

Enterprise buyers find ThreatLocker's pricing competitive and flexible, valuing its affordability, transparency, and accessible setup costs.
Trellix Network Detection is costly but effective, with yearly licensing, discounts, and competitive pricing against some competitors like Palo Alto.
After conversations with other partners, it became clear we underpriced it initially, which caused most of our issues.
We are moving towards the Unified solution, where they basically bundle everything together, providing us better stability with the ability to bring in new product offerings without having to go back to the customer and say, 'This is going to cost you.'
I had a really good deal at the time, and it continues to be cost-effective.
 

Valuable Features

ThreatLocker Zero Trust Platform enhances security with features like application control, selective elevation, and robust network access controls.
Trellix excels in threat protection with AI-driven analysis, automation, and enhanced visibility, benefiting security operations and incident management.
ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications has been excellent.
It protects our customers.
The major benefit is fewer breaches overall, as nothing can be run without prior approval. This helps my company protect its data and secure itself effectively.
Trellix NDR provides an essential defense by automatically responding to network incidents that firewalls may not catch.
 

Categories and Ranking

ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
6th
Average Rating
9.2
Reviews Sentiment
7.6
Number of Reviews
39
Ranking in other categories
Network Access Control (NAC) (5th), Endpoint Protection Platform (EPP) (6th), Application Control (2nd), ZTNA (3rd), Ransomware Protection (3rd)
Trellix Network Detection a...
Ranking in Advanced Threat Protection (ATP)
14th
Average Rating
8.4
Reviews Sentiment
7.3
Number of Reviews
39
Ranking in other categories
Network Detection and Response (NDR) (12th)
 

Mindshare comparison

As of April 2025, in the Advanced Threat Protection (ATP) category, the mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 2.7%, up from 1.7% compared to the previous year. The mindshare of Trellix Network Detection and Response is 4.8%, down from 4.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Johnathan Bodily - PeerSpot reviewer
Ensures ransomware protection and reduces phishing chaos
The application control has been great so far, and while I am still exploring the network access controls, I unfortunately don't have access to one module I would love to have due to licensing restrictions. It's easy to use in regard to reducing attack surfaces. For me, it's a piece of cake. We can have something approved within 30 seconds, thanks to the mobile app. We haven't eliminated security solutions. We just add to it, and ThreatLocker has been a great addition. We also have Kaseya and ThreatLocker as a supplement to that. It's useful. They have overlap, and we look at the overlap as a good thing. It's helped your organization save on operational costs or expenses by ensuring that many fewer hours are spent dealing with ransomware nonsense. I cannot count the amount of hours that I personally have not had to put in to recovering an environment from a ransomware event. The last big one took us about three weeks to completely recover from. Since we've grouped ThreatLocker in, the management of that whole setup has gone down to just daily help desk tasks and general server maintenance instead of having the whole system on fire. There are probably thousands of hours of saved time between our teams. It's been great so far. ThreatLocker Zero Trust Endpoint Protection Platform's ability to block access to unauthorized applications is great. It's my biggest protection, the blocked applications. In a lot of cases, you go to install something yourself that you need for management, and it comes in and says, nope. And then I have to log into the portal and approve it. I get our other guys saying, hey, why are you trying to approve something? Any of the tools that I'm using on a day-to-day basis that haven't been in the environment during the whole learning mode initially, I could go through and set extensions and all that. So, while it's a headache on that end, the amount of saved time I can't even count. It is a little frustrating on my end since I like to go as quickly as I possibly can, and it slows me down. However, that's a really good thing. Depending on the site, it can save a lot of time and cut down headaches. It's likely saved a week's worth of time. It's cut down the amount of sever help desk tickets. Those have become minimal.
BiswabhanuPanda - PeerSpot reviewer
Offers in-depth investigation capabilities, integrates well and smoothly transitioned from a lower-capacity appliance to a higher one
The in-depth investigation capabilities are a major advantage. When the system flags something as malicious, it provides a packet capture of that activity within the environment. That helps my team quickly identify additional context that most other tools wouldn't offer – like source IP or base64 encoded data. We can also see DNS requests and other details that aren't readily available in solutions like Check Point or others that we've tried. The detection itself is solid, and their sandboxing is powerful. There's a learning curve – you need a strong grasp of OS-level changes, process forking, registry changes, and the potential impact of those. But with that knowledge, the level of information Trellix provides is far greater than what we've seen elsewhere. The real-time response capability of Trellix has been quite effective, although it's not very fast. The key is this solution's concept of 'preference zero.' They don't immediately act on a zero-day. For example, the solution has seen a piece of malware for the first time. It'll let it in, then do sandboxing. Maybe after four or five minutes, it identifies that specific file's DNX Secure Store as malicious. At that point, they update the static analysis engine, and it gets detected if anything else tries to download the same file. There is that initial 'preference zero' concept, like with Panda. You may not hold traffic in the network. That's standard in the industry; we don't do much about it. To address that, we also have endpoint solutions. We use SentinelOne in our environment, which helps us identify threats like Western Bureaus and others.
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Top Industries

By visitors reading reviews
Computer Software Company
37%
Retailer
8%
Manufacturing Company
5%
Financial Services Firm
5%
Financial Services Firm
17%
Comms Service Provider
11%
Computer Software Company
10%
Manufacturing Company
9%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
We have encountered a few challenges regarding pricing, contract renewals, and additions. As we explored adding features like Cyber Hero, it proved to be an increased expense for our clients. This ...
What needs improvement with ThreatLocker Allowlisting?
I find that the learning mode is too accessible. Technicians sometimes default to it instead of manually building policy controls. I would prefer the learning mode to be harder to access, ideally h...
What do you like most about FireEye Network Security?
We wanted to cross-reference that activity with the network traffic just to be sure there was no lateral movement. With Trellix, we easily confirmed that there was no lateral network involvement an...
What is your experience regarding pricing and costs for FireEye Network Security?
While I do not handle pricing directly, it is known that there is a variety of customers with different licensing needs, which depends on the organization's size and policy.
What needs improvement with FireEye Network Security?
The Trellix solution could be improved by enhancing the Central Management Console for faster visibility, which would help in network detection response. Networking often involves complexity that c...
 

Also Known As

Protect, Allowlisting, Network Control, Ringfencing
FireEye Network Security, FireEye
 

Overview

 

Sample Customers

Information Not Available
FFRDC, Finansbank, Japan Advanced Institute of Science and Technology, Investis, Kelsey-Seybold Clinic, Bank of Thailand, City of Miramar, Citizens National Bank, D-Wave Systems
Find out what your peers are saying about ThreatLocker Zero Trust Endpoint Protection Platform vs. Trellix Network Detection and Response and other solutions. Updated: March 2025.
846,617 professionals have used our research since 2012.