I use two versions currently. The latest version that's just come out and the 2022 versions.
Currently, I'm using the solution to pull APC data using the data collection. I've got to transform the data massively to make it usable, so I use FME for huge amounts of transformation and to put it into ArcGIS Enterprise. FME is a ZTL as well, specifically the "L" bit. I also use FME for a lot of analysis where we want it quick and efficient on big datasets that ArcGIS Pro is unrealistic to do on.
I also use FME, where if somebody sends me a spreadsheet where, for example, we would need to get everything in capital letters, it's quicker for me to capitalize everything in FME Workbench than it is in Excel.
I can use FME for just about everything, from logging processes to looking at file structures, what's changed in file structures, what people are doing, or what they've updated. It's not just need-to-know. It's a massive piece of software that's also coded in Python. What FME can't do, I then write in Python.
I can make FME pull in ArcPy, which means that for every single thing that ArcGIS Pro can do, I can make FME. It's much bigger than the box.