We use Loom as a service desk solution for incident request changes, problem management and the like. It's not just service desk, it's an IT service management platform, primarily but it can also be used for asset management, or just as a static database. But it can also be integrated with a lot of other tools as well. It's usually used as an ITSM tool, but I know people have also used the security module. One of my customers also uses the HR module. I've implemented the solution numerous times.
In my last installation there were 1,200 resolvers and 600 approvers on top of that. The solution is used mainly in medium to large enterprises. For small enterprise, I think it would be too expensive.
I'm a consultant and don't receive any financial benefit from recommending Loom and I also implement other service tools. It depends on what the client wants and the budget. If they have the budget, then my personal preference is ServiceNow's Loom. But I always have to put forward a minimum of five suggestions depending on functionality and cost.