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Cisco Secure Email Threat Defense vs Cloudflare One comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Mar 16, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Sponsored
Ranking in Email Security
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
48
Ranking in other categories
Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Cloudflare One
Ranking in Email Security
11th
Average Rating
8.8
Reviews Sentiment
7.3
Number of Reviews
20
Ranking in other categories
Secure Web Gateways (SWG) (7th), Data Loss Prevention (DLP) (7th), Cloud Access Security Brokers (CASB) (7th), Distributed Denial-of-Service (DDoS) Protection (5th), Access Management (5th), Bot Management (3rd), ZTNA as a Service (3rd), ZTNA (2nd), Secure Access Service Edge (SASE) (6th), Remote Browser Isolation (RBI) (2nd)
 

Mindshare comparison

As of April 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 13.1%, down from 19.0% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, down from 1.2% compared to the previous year. The mindshare of Cloudflare One is 1.6%, up from 1.3% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
Carlos Alam Hernandez Baruch - PeerSpot reviewer
The solution enables seamless security management and fosters a learning environment
Feedback could be enhanced. While I work efficiently with Clover as a partner in Mexico City, sometimes the information and requests are easier to manage with more concrete solutions. For the solution stopping us for e-learning, I appreciate the concept yet need more resources or courses in Mexico, preferably in Spanish. Certifications are easy, however, I require more real-world environments and instructors.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Our customers are satisfied with Defender for 365 because Microsoft products are easy to use and customize to meet the client's needs. Everything is in one place, so we can adjust policies as needed for phishing, DLP, ATP, or any other security features that our clients want to apply."
"The most valuable aspect of Microsoft Defender for Office 365 is its ability to protect us from malware."
"Some of the valuable features on the email side are anti-phishing, anti-malware, and Safe Links."
"Since we have started using the solution, there have been fewer compromises."
"The initial setup was easy."
"It’s easy to handle integrations, and we don't need a lot of people in our IT team."
"Microsoft Defender for Office 365's most valuable features are safe attachments and safe links."
"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"The product offers protection, email security, anti-spam, and antivirus."
"Secure Email Threat Defense's scalability is good."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"This solution is easy to use."
"Cisco has a threat mechanism called cloud-based Talos, where all the threats are inbuilt."
"The solution is stable."
"It has an efficient email filtering feature."
"I highly recommend it as one of the best choices."
"Clover is the best product globally."
"Cloudflare is simple to use."
"Cloudflare DDoS mitigates DDoS attacks."
"Cloudflare Zero Trust Platform removes the risk of exposing the applications to the public."
"The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good."
"Cloudflare is by far the most effective solution that I have come across."
"The best feature is rate limiting. If I'm expecting 500 visits per hour, Cloudflare will limit the requests if I suddenly get 50,000."
"The solution has different options that can be used to differentiate DDoS attacks."
 

Cons

"There needs to be an improvement in integrating the product to work across multiple operating systems, and to have better support for non-Microsoft file types."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"One area for improvement is support, in terms of being able to reach them and, especially, technical support for configuration."
"In one of the reports I can get the exact place where a vulnerable file resides. But for that, I need to explicitly go into the device and check. If they could include that file part in the report, without my having to go to the device itself, that would help."
"Microsoft wants its well-paying customers to finish testing some of its half-baked products, find bugs, and report bugs back to Microsoft's team, which is a little frustrating for those who have to manage it and roll it up to thousands of people across the organization."
"I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost."
"Sometimes, phishing emails manage to pass through the filter, so the system needs to enhance its phishing email detection capabilities."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"We encounter issues while searching for missing emails."
"The physical appliance has been discontinued, although the platform still exists."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"This solution could be improved by integration with Sandbox."
"From a technical point of view, Cisco is far behind in terms of cybersecurity, and it has to improve very much."
"The pricing could always be better."
"Cisco Secure Email Cloud Mailbox can improve by adding advanced phishing, then the solution would become the best in the market. However, this could increase the price even more. Additionally, if CES with domain protection could be added it would be an even better solution."
"The response time for support must be reduced."
"Operating and tuning the product is difficult."
"Lacks a VPN feature to provide a secure connection to the data center."
"Cloudflare DDoS has poor technical support."
"Feedback could be enhanced."
"Cloudflare Zero Trust Platform needs to improve its documentation. It took time to do the implementation."
"They don't have a person to provide support for customers using the solution under their free plan."
"For the topic of improvement, providing some training material is one of my suggestions."
 

Pricing and Cost Advice

"It's a user-base subscription."
"The license is expensive because the cost is based on the number of users."
"The solution could be better by simplifying the business model of their licensing. It was hard to figure out how to get the licensing done for the environment, initially."
"The pricing has become expensive."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
"It is much more expensive than using another solution because we have had to include some options and upgrade our license."
"The pricing is normal. Considering its popularity, it's not overpriced."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"The feedback from vendors and customer is that it is expensive."
"The solution’s pricing is manageable."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"It is expensive compared to other vendors."
"The solution is not that expensive."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"The solution's pricing lacks transparency."
"The prices are slightly expensive."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"Cloudflare Zero Trust Platform's pricing is good."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
35%
Healthcare Company
7%
Government
5%
Comms Service Provider
5%
Computer Software Company
16%
Financial Services Firm
10%
Comms Service Provider
9%
Manufacturing Company
6%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Money-wise, it is a part of the Office 365 ( /products/office-365-reviews ) suite, making it slightly more expensive ...
What needs improvement with Microsoft Defender for Office 365?
The main area for improvement is simplifying the implementation and rollout process. There are many conditions to be ...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
What do you like most about Cloudflare Access?
The tool also offers good scalability, and the dashboard, along with real-time analytics, is very good.
What is your experience regarding pricing and costs for Cloudflare Access?
The price of Cloudflare Access is the same as compared to Akamai, but I get better performance from Cloudflare. My co...
What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
 

Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
23andMe
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Cloudflare One and other solutions. Updated: April 2025.
847,862 professionals have used our research since 2012.