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Microsoft Defender for Office 365 vs ThreatLocker Zero Trust Endpoint Protection Platform comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 19, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.4
Microsoft Defender for Office 365 enhances security, reduces costs, integrates effectively with Microsoft tools, and boosts productivity, offering significant ROI.
Sentiment score
8.2
ThreatLocker enhances security and productivity with real-time protection, leading to revenue growth and improved efficiency in one year.
It has also decreased our time to detection and response by about 15 to 20 percent.
The measurable benefits of using ThreatLocker include ensuring real-time protection of organizational resources and maintaining user authentication and protection levels to reduce risks.
 

Customer Service

Sentiment score
7.0
Microsoft Defender for Office 365 support is praised for responsiveness, though some users note templated responses and outdated documentation.
Sentiment score
8.4
ThreatLocker Zero Trust Endpoint Protection offers highly-rated, efficient customer service, with rapid response times and knowledgeable support, achieving user satisfaction.
Customer service and support have been fantastic.
ThreatLocker's technical support process could be streamlined by reducing the number of steps required to reach a human agent.
It could be better, especially with response times.
 

Scalability Issues

Sentiment score
8.1
Microsoft Defender for Office 365 is highly scalable and easily accommodates thousands of users without performance issues, simplifying growth.
Sentiment score
8.3
ThreatLocker efficiently scales for all business sizes, seamlessly managing thousands of endpoints without issues, supporting diverse infrastructures.
 

Stability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 is reliable and stable, boasting 99.9% availability and prompt resolutions to minor bugs.
Sentiment score
6.8
ThreatLocker offers stable endpoint protection, with minimal issues that are quickly resolved, enhancing reliability and performance for users.
Stability can be improved as there are times it goes down or requires management to adjust policies.
 

Room For Improvement

Microsoft Defender for Office 365 requires enhancements in virus blocking, phishing detection, integration, scalability, support, and pricing transparency.
ThreatLocker could enhance its platform with flexible training, user interface improvements, better integrations, and more comprehensive support.
I would reduce the cost.
This is problematic when immediate attention is needed.
Comprehensive 24-hour log monitoring is a valuable enhancement for both business and enterprise-level users.
 

Setup Cost

Microsoft Defender for Office 365 is cost-effective for large enterprises but perceived as expensive for smaller businesses.
Enterprise users value ThreatLocker's cost-effective Zero Trust Platform for its comprehensive features, excellent support, and customizable tiered pricing.
 

Valuable Features

Microsoft Defender for Office 365 provides comprehensive protection with seamless integration, simplifying security management and safeguarding remote work environments.
ThreatLocker offers mobile access, zero trust protection, granular control, and support, enhancing security and reducing management costs.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
ThreatLocker's most valuable feature is its scanning capability, which executes all types of executable files.
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
47
Ranking in other categories
Email Security (1st), Microsoft Security Suite (11th)
ThreatLocker Zero Trust End...
Ranking in Advanced Threat Protection (ATP)
8th
Average Rating
9.0
Reviews Sentiment
7.5
Number of Reviews
18
Ranking in other categories
Network Access Control (NAC) (5th), Endpoint Protection Platform (EPP) (11th), Application Control (4th), ZTNA (8th), Ransomware Protection (5th)
 

Mindshare comparison

As of February 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 10.4%, down from 15.0% compared to the previous year. The mindshare of ThreatLocker Zero Trust Endpoint Protection Platform is 2.6%, up from 1.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Musah Ibrahim - PeerSpot reviewer
Highly effective at controlling applications and securing our systems
As an architecture firm, we rely on TAISE’s Cybersecurity-as-a-Service (CaaS) to keep our systems safe from malware threats. TAISE introduced us to ThreatLocker, which has become essential in safeguarding our infrastructure by blocking unapproved applications and defending against unknown malware. Given our exposure to frequent malware, ThreatLocker, through TAISE's expert implementation, has proven invaluable ThreatLocker Protect is very simple and easy to understand. You do not need much technical knowledge to be able to use it. It is very good. Anybody with a bit of IT knowledge is able to handle it. Ringfencing adds an extra layer of defense. If an application is compromised, you can just exclude the computer and do your troubleshooting and find out what the problem was. It goes hand in hand with application whitelisting. It has been very helpful. It adds an extra security system which is very much needed for our infrastructure. ThreatLocker Protect has improved my organization greatly. Before using ThreatLocker Protect, we experienced a malware attack that caused significant damage, corrupting many of our files. Since implementing ThreatLocker Protect, we have not faced any such issues, and our operations have been smooth. We were able to realize its benefits immediately. No user can install any unknown applications or unauthorized applications on their own. I have been able to manage my systems effectively without any malware. ThreatLocker Protect has reduced our help desk tickets by about 40%, as every software they use is approved by me before use, limiting unauthorized installations. ThreatLocker Protect has freed up a lot of time. I do not have to do much with the help desk because our systems are protected with ThreatLocker Protect.
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Top Industries

By visitors reading reviews
Computer Software Company
17%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
37%
Retailer
8%
Financial Services Firm
5%
Government
5%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
I don't have detailed specifics on pricing, setup cost, or licensing.
What needs improvement with Microsoft Defender for Office 365?
I am generally satisfied with how it currently is. If I could improve anything, I would reduce the cost.
What do you like most about ThreatLocker Allowlisting?
The interface is clean and well-organized, making it simple to navigate and find what we need.
What is your experience regarding pricing and costs for ThreatLocker Allowlisting?
I handle the technical aspects, while my manager deals with pricing. Although the pricing seems good, there have been inconsistencies in contract negotiations. What we are told during calls sometim...
What needs improvement with ThreatLocker Allowlisting?
ThreatLocker would benefit from incorporating an antivirus feature or comprehensive 24-hour log monitoring, a valuable enhancement for both business and enterprise-level users.
 

Also Known As

MS Defender for Office 365
Protect, Allowlisting, Network Control, Ringfencing
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Information Not Available
Find out what your peers are saying about Microsoft Defender for Office 365 vs. ThreatLocker Zero Trust Endpoint Protection Platform and other solutions. Updated: January 2025.
832,138 professionals have used our research since 2012.