Yes, EDR will replace traditional A/V with most solutions. Make sure to validate with your vendor but the reputable ones certainly cover A/V. You do not need to have both as this is unnecessary overhead. Any (reputable) EDR will have known bad MD5 already included.

There are several good ones and it depends on budget, integrations needed, staff levels, etc. Crowdstrike Falcon is great if you can afford it. Price reflects "set it and forget it" type of EPP. No need to hire FTE to manage it and comes with 24x7x365 SOC. If you can…