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Cisco Secure Email Threat Defense vs Menlo Protect comparison

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Comparison Buyer's Guide

Executive SummaryUpdated on Dec 3, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
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Ranking in Email Security
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
48
Ranking in other categories
Advanced Threat Protection (ATP) (1st), Microsoft Security Suite (11th)
Cisco Secure Email Threat D...
Ranking in Email Security
20th
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
13
Ranking in other categories
No ranking in other categories
Menlo Protect
Ranking in Email Security
43rd
Average Rating
9.0
Reviews Sentiment
7.3
Number of Reviews
2
Ranking in other categories
Internet Security (12th), Enterprise Browsers (8th), Remote Browser Isolation (RBI) (3rd)
 

Mindshare comparison

As of April 2025, in the Email Security category, the mindshare of Microsoft Defender for Office 365 is 13.1%, down from 19.0% compared to the previous year. The mindshare of Cisco Secure Email Threat Defense is 1.1%, down from 1.2% compared to the previous year. The mindshare of Menlo Protect is 0.3%, down from 0.4% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
Mike Bulyk - PeerSpot reviewer
Can quickly identify, track, tag, and categorize internal emails. Reporting accessibly via the main dashboard would be a great addition.
If Cisco could continue to develop integrations, whether it's internal tooling, Threat Grid, or AMP reporting which could be accessible via a single web page, that would be helpful. This would essentially add additional context on messages as well as files or links being detected. Potentially adding additional context on why certain messages are tagged as spam or malware. In our case, malware hasn't been detected yet, but spam certainly has been. Knowing what engines or which components of the message make it identifiable as spam, that could be useful. Additional context and reporting accessibly via the main dashboard would be great. There is still room for improvement in terms of integrations with other Cisco tools and non-Cisco tools. There is also some room for improvement needed in terms of the reporting.
Gerard GLOWKA - PeerSpot reviewer
Stable and scalable solution with a great threat isolation engine
Menlo Security RBI is mainly used to do basic cloud migrationary technologies Menlo Security RBI's best feature is its threat isolation engine. Menlo Security RBI could be more cloud-friendly, and its mobility could be improved. In the next release, I'd like Menlo Security RBI to include a…

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"The stability of Microsoft Defender for Office 365 is fantastic."
"The most valuable feature is the integration. It's a single console, so we don't have to switch around between multiple products. Another valuable feature is the ease of operations and maintenance."
"Microsoft Defender for Office 365 facilitates efficient management and updates through the cloud. We do not have to worry about incompatibilities. It just works."
"Defender for 365 is a comprehensive cloud-based solution. The value of the cloud is that you aren't alone. Threat intelligence and analytics are shared in the cloud. We don't have to find the solution alone. If you face an unknown threat with traditional solutions like Trend Micro and Symantec, you need to open a case and send your information to them to analyze forensically and identify the source of the attack."
"Microsoft Defender has a feature to protect each and every attachment. Even if it's an encrypted attachment, it will check for any potential threats."
"The email protection is excellent, especially in terms of anti-phishing policies."
"I like its investigation capabilities, as that is what is most important to me. It is fairly simple with a user-friendly interface."
"On ease of use, it rates very high. It's something that I was able to get into without really looking at any documentation. I wanted to see what it felt like before I started looking at any documentation on how to use it, and it was very easy to use. It works very smoothly. The user experience is very intuitive. They did an amazing job on that."
"The ability to see east-west traffic is its most valuable feature. Traditionally, email defense focuses on north-south, inbound-outbound, egress-ingress traffic. With Cisco Secure Email Cloud Mailbox, it's able to quickly identify, track, tag, and categorize emails that are internal. That can typically give us visibility into if there's an internal compromised account (for example). Someone can then use that internal compromised account to email additional accounts with either malicious software or links, but internal within that Office tenant. Effectively, that email message never leaves the tenant. Any of the mail gateways really do not have any method or way of seeing this traffic since it's not leaving the environment."
"It's very easy to deploy and configure."
"The solution is stable."
"Secure Email Threat Defense's scalability is good."
"I highly recommend it as one of the best choices."
"The features and functionalities are much better than Microsoft's in-built Defender plan."
"The product offers protection, email security, anti-spam, and antivirus."
"I can't say that there is one specific feature that is most valuable. It's the overall platform that is well-suited to our needs. It's something that is different from a lot of other products or platforms in the marketplace."
"Menlo Security RBI's best feature is its threat isolation engine."
 

Cons

"The custom alerts have to improve a lot."
"The product must provide better malware detection."
"We need a separate license and we don't know how to get the license that is required."
"This product's effectiveness could be improved, in terms of detecting unwanted spam or even malware between the emails, compared to other products."
"Configuration at the mid-level could be improved for the support team."
"There's room for improvement regarding the time frame for retrieving emails."
"About eight months ago, we started to measure the quantity of phishing and spam that we have been receiving, and it has been increasing a lot. That means that protection for our email is not as good as we were expecting."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"This solution could be improved by integration with Sandbox."
"Cisco's multiple product lines and verticals made this just one of their many verticals, and we could see a shift in focus."
"Customers will benefit greatly from monthly billing because the majority of customers today use the cloud, be it Office 365, or Google Cloud."
"The search area has room for improvement. When you go to the next page, it remains at the bottom of the current page that you're on. Also, under the reports section, it allows you to see any "convictions," but if you want to search for those convictions you have to remember when they all came in and go back and edit the search accordingly. You cannot click on the list of convictions to actually see if you had a spike at a certain time."
"The pricing could always be better."
"We encounter issues while searching for missing emails."
"The tool gives false positives and it needs to be more accurate. I would like to see AI as a new feature."
"The physical appliance has been discontinued, although the platform still exists."
"Menlo Security RBI could be more cloud-friendly, and its mobility could be improved."
"There are several features, such as supporting web technologies, that the company is working on implementing in the platform. There are a lot of backend web technologies in use on various websites, for example, two-way audio/video and WebGL, for which support may not be fully implemented in the product."
 

Pricing and Cost Advice

"I was working in the government and it was too expensive for us to use our Microsoft products."
"The pricing is normal. Considering its popularity, it's not overpriced."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"The pricing has become expensive."
"The product is expensive."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"Cisco Secure Email Cloud Mailbox does not have any competition with Sophos, Trend Micro, or other vendors of the world. However, there is a pricing premium for the solution. One has to look at it from that angle that while they are buying Cisco, there will be a premium, and Cisco justifies that premium value. That's why they're charging a high price."
"The solution’s pricing is manageable."
"It is expensive compared to other vendors."
"The feedback from vendors and customer is that it is expensive."
"Menlo Security RBI can be very costly."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Computer Software Company
35%
Healthcare Company
7%
Government
5%
Comms Service Provider
5%
Computer Software Company
15%
Financial Services Firm
13%
Government
9%
Insurance Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
No data available
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of variou...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Money-wise, it is a part of the Office 365 ( /products/office-365-reviews ) suite, making it slightly more expensive ...
What needs improvement with Microsoft Defender for Office 365?
The main area for improvement is simplifying the implementation and rollout process. There are many conditions to be ...
What do you like most about Secure Email Threat Defense?
Secure Email Threat Defense's scalability is good.
What is your experience regarding pricing and costs for Secure Email Threat Defense?
Cisco's closest competition is Proofpoint. Both are in the same range in terms of pricing. Pricing is on the higher s...
What needs improvement with Secure Email Threat Defense?
The physical appliance has been discontinued, although the platform still exists. Improvements here and there could b...
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Also Known As

MS Defender for Office 365
Cisco Secure Email Cloud Mailbox, Cisco CMD, Cisco Cloud Mailbox Defense
Menlo Security Email Security, Menlo Security Remote Browser Isolation
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Luiss University, Lone Star College, T-Systems, Magyar Telekom
Macy's, HSBC, Bank of Hawaii
Find out what your peers are saying about Cisco Secure Email Threat Defense vs. Menlo Protect and other solutions. Updated: April 2025.
847,862 professionals have used our research since 2012.