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ESET PROTECT Enterprise vs Microsoft Defender for Endpoint comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Nov 2, 2025

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.0
ESET PROTECT Enterprise offers strong returns with effective security, easy installation, and up to 30% cost savings over CrowdStrike.
Sentiment score
6.9
Microsoft Defender for Endpoint offers significant ROI with cost savings, seamless integration, and real-time protection against ransomware attacks.
The return on investment is excellent due to its functionality and ease of installation.
Director, Information Technology at Premier Realty Group
There was money saving from using ESET PROTECT Enterprise, which is why I switched from CrowdStrike to ESET.
IT Manager at R K Khanna and Associates
Without detection and protection measures, organizations would face substantial payments and reputational damage, including the necessity to inform customers about data breaches, potentially leading to loss of business.
Consultant at ACT4SERVICES
We have seen a return on investment when using Microsoft Defender for Endpoint, as it saves labor by reducing the need for staff to focus on it.
IT CONSULTANT at a tech company with 10,001+ employees
The biggest return on investment for me when using Microsoft Defender for Endpoint is the time saving.
Lead security engineer at a computer software company with 11-50 employees
 

Customer Service

Sentiment score
7.9
Customers praise ESET PROTECT Enterprise's support team for being knowledgeable, responsive, and helpful, often rating them 9 or 10.
Sentiment score
6.4
Many users find Microsoft Defender for Endpoint reliable, but support experiences vary, with premium support offering quicker assistance.
The tech support from ESET is amazing, and I would rate it as ten out of ten.
Owner at Octo-Xpressions
They are very responsive and help in solving issues quickly.
Security Network Engineer at АТ "Банк інвестицій та заощаджень"
Even if support is addressing my problem, if the two issues I mentioned are not resolved, then the support process is not complete.
IT Manager at R K Khanna and Associates
The Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, 'Just to set expectations, my lunch break is in an hour and I am going to go away then.'
Security Analyst III at a healthcare company with 10,001+ employees
The level-one support seems disconnected from subject matter experts.
Office 365 Subject Expert at a government with 10,001+ employees
I rate Microsoft support 10 out of 10.
Team manager of it department at a financial services firm with 501-1,000 employees
 

Scalability Issues

Sentiment score
7.5
ESET PROTECT Enterprise is highly scalable, efficiently expanding to thousands of devices, with performance varying across workstations and servers.
Sentiment score
7.4
Microsoft Defender for Endpoint is scalable and integrates well with Microsoft’s ecosystem, despite needing improvements for handling massive data.
It can efficiently scale up to thousands of devices in an organization without issues.
Owner at Octo-Xpressions
I have used many products before, and this solution is definitely scalable.
IT Manager at R K Khanna and Associates
It is better suited for workstations rather than server environments.
Director, Information Technology at Premier Realty Group
We managed to scale it out in a short amount of time, with two months of planning and three months of implementation on 10,000 computers.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint is scalable enough to handle various devices across environments, whether they are laptops, Android devices, or operating in hybrid environments.
Snr. Infrastructure Architect (Data Centre) at LogicEra
Compatibility is its main feature.
IT CONSULTANT at a tech company with 10,001+ employees
 

Stability Issues

Sentiment score
7.4
ESET PROTECT Enterprise operates reliably with minimal maintenance, despite occasional update interruptions and manageable false positives.
Sentiment score
7.9
Microsoft Defender for Endpoint is praised for its reliability and stability, with minor concerns about resource intensity and performance.
When it performs an update, ESET PROTECT Enterprise should request permission for restarting because otherwise, users lose their work.
IT Manager at R K Khanna and Associates
The solution is stable, and I have not encountered any glitches.
Owner at Octo-Xpressions
The solution is very, very stable.
Director, Information Technology at Premier Realty Group
I haven't seen any outages with Microsoft.
IT Security Engineer at a financial services firm with 1,001-5,000 employees
I rate Defender 10 out of 10 for stability.
Team manager of it department at a financial services firm with 501-1,000 employees
Defender for Endpoint is extremely stable.
Systems engineers at Delta Dental of Colorado
 

Room For Improvement

ESET PROTECT Enterprise needs better deployment, performance, automation, UI clarity, and efficient management, especially for mobile and Mac.
Microsoft Defender for Endpoint faces interface complexity, slow detection, high CPU usage, integration issues, and seeks improvements in multiple areas.
Sometimes, agents lose connection with the management console, and the administration team needs to reinstall the agents on the computers.
Security Network Engineer at АТ "Банк інвестицій та заощаджень"
They need to reduce the number of notifications on the endpoints.
Director, Information Technology at Premier Realty Group
It takes a lot of processing power when the machine is initially booted.
Owner at Octo-Xpressions
Repeated interactions are necessary due to Level One's lack of tools and knowledge, hindering efficient problem-solving and negatively impacting our experience with Microsoft support.
Office 365 Subject Expert at a government with 10,001+ employees
In contrast, competing products offer reduced pricing for long-term commitments, which makes it difficult for us in that environment.
Solution Consultant at BIM Group of Companies
We use Microsoft partners to help govern the platform, and as part of an alliance, we want to gather data from each tenant and combine them for a complete view.
Team manager of it department at a financial services firm with 501-1,000 employees
 

Setup Cost

ESET PROTECT Enterprise's pricing is seen as cost-effective, offering good value despite being higher than some competitors.
Microsoft Defender for Endpoint offers flexible pricing, making it competitive and cost-effective compared to standalone security products.
I pay 40 dollars per agent annually, which is cheaper than 60 dollars per agent for Check Point.
Security Network Engineer at АТ "Банк інвестицій та заощаджень"
We recently paid fourteen dollars and thirty-six cents per unit for 20 users, which is reasonable.
Director, Information Technology at Premier Realty Group
Comparing it to other solutions in the market, it was slightly higher.
IT Manager at R K Khanna and Associates
That has been the trend we have seen with Microsoft lately—it is just getting more and more expensive.
Assistant Director, Hybrid Infrastructure & Operations at a insurance company with 501-1,000 employees
Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs.
Team manager of it department at a financial services firm with 501-1,000 employees
It costs $15 per VM for the P2 plan, which is seen as affordable for customers.
Snr. Infrastructure Architect (Data Centre) at LogicEra
 

Valuable Features

ESET PROTECT Enterprise offers robust security with efficient management, minimal resources, and strong threat detection for online transactions.
Microsoft Defender for Endpoint excels with seamless integration, advanced threat intelligence, AI-driven protection, and continuous cloud-based security management.
It allows simple whitelisting and has a learning mode for new installations, which reduces false positives by adapting to typical user habits.
Director, Information Technology at Premier Realty Group
Its web component prevents infections from malicious websites, which enhances its anti-malware capabilities.
Owner at Octo-Xpressions
One of the strong features of ESET PROTECT Enterprise is its ability to work well on old computers.
Security Network Engineer at АТ "Банк інвестицій та заощаджень"
Defender for Endpoint's coverage across different platforms in our environment is pretty good. We have devices running Linux, Mac OS, Windows, iOS, and Android. It covers all of them.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint provides a unified management interface allowing customers to manage their on-premises and hybrid infrastructures from a single pane.
Snr. Infrastructure Architect (Data Centre) at LogicEra
One of the best features of Microsoft Defender for Endpoint is its database for identifying zero-day attacks or malware attacks.
Consultant at ACT4SERVICES
 

Categories and Ranking

ESET PROTECT Enterprise
Ranking in Anti-Malware Tools
10th
Average Rating
8.8
Reviews Sentiment
7.0
Number of Reviews
16
Ranking in other categories
Extended Detection and Response (XDR) (19th)
Microsoft Defender for Endp...
Ranking in Anti-Malware Tools
1st
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
210
Ranking in other categories
Endpoint Protection Platform (EPP) (2nd), Advanced Threat Protection (ATP) (3rd), Endpoint Detection and Response (EDR) (2nd), Microsoft Security Suite (3rd)
 

Mindshare comparison

As of January 2026, in the Anti-Malware Tools category, the mindshare of ESET PROTECT Enterprise is 2.2%, up from 1.4% compared to the previous year. The mindshare of Microsoft Defender for Endpoint is 9.1%, down from 17.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Anti-Malware Tools Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Endpoint9.1%
ESET PROTECT Enterprise2.2%
Other88.7%
Anti-Malware Tools
 

Featured Reviews

Manikumar David - PeerSpot reviewer
IT Manager at R K Khanna and Associates
Provides comprehensive monitoring and policy implementation with room for memory optimization
ESET PROTECT Enterprise makes the system a little slow sometimes and updates occur at startup. Sometimes unwanted pop-ups appear to users, and they are unable to disable them. The user-friendliness is lacking in some areas. When users are using any computer, ESET PROTECT Enterprise should work in the background without consuming much memory, and any updates should proceed in the background without disturbing the user.
Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
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Top Industries

By visitors reading reviews
Computer Software Company
15%
Comms Service Provider
13%
Financial Services Firm
10%
Government
9%
Computer Software Company
12%
Manufacturing Company
9%
Government
8%
Financial Services Firm
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business11
Midsize Enterprise2
Large Enterprise2
By reviewers
Company SizeCount
Small Business80
Midsize Enterprise40
Large Enterprise92
 

Questions from the Community

What needs improvement with ESET Protect?
One area for improvement in ESET PROTECT Enterprise is its capabilities on Mac devices, which are less functional compared to Windows. In terms of device management, ESET PROTECT Enterprise could i...
What is your primary use case for ESET Protect?
My customers use ESET PROTECT Enterprise to secure all their operating systems; we have a lot of customers who rely on this antivirus. It also acts as a platform where I can manage all the devices ...
What advice do you have for others considering ESET Protect?
I suggest that other users considering ESET PROTECT Enterprise utilize this platform to manage all their laptops and apply security policies effectively to protect their Windows environments. On a ...
How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
 

Also Known As

ESET Protect, ESET File Security
Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Information Not Available
Petrofrac, Metro CSG, Christus Health
Find out what your peers are saying about ESET PROTECT Enterprise vs. Microsoft Defender for Endpoint and other solutions. Updated: December 2025.
879,711 professionals have used our research since 2012.