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Microsoft Defender for Endpoint vs Trend Micro Smart Protection comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Sep 9, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
6.9
Microsoft Defender for Endpoint offers significant ROI with cost savings, seamless integration, and real-time protection against ransomware attacks.
Sentiment score
4.8
Trend Micro Smart Protection delivers positive ROI, preventing breaches, updating systems, and supporting financial and reputational benefits over time.
Without detection and protection measures, organizations would face substantial payments and reputational damage, including the necessity to inform customers about data breaches, potentially leading to loss of business.
Consultant at ACT4SERVICES
We have seen a return on investment when using Microsoft Defender for Endpoint, as it saves labor by reducing the need for staff to focus on it.
IT CONSULTANT at a tech company with 10,001+ employees
The biggest return on investment for me when using Microsoft Defender for Endpoint is the time saving.
Lead security engineer at a computer software company with 11-50 employees
 

Customer Service

Sentiment score
6.4
Many users find Microsoft Defender for Endpoint reliable, but support experiences vary, with premium support offering quicker assistance.
Sentiment score
5.1
Trend Micro Smart Protection's customer service varies; premium is effective, but standard support often faces delays and availability issues.
The Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, 'Just to set expectations, my lunch break is in an hour and I am going to go away then.'
Security Analyst III at a healthcare company with 10,001+ employees
The level-one support seems disconnected from subject matter experts.
Office 365 Subject Expert at a government with 10,001+ employees
I rate Microsoft support 10 out of 10.
Team manager of it department at a financial services firm with 501-1,000 employees
The agent is very light, and it doesn't cause any issues on the machine.
Solutions Architect at a tech services company with 51-200 employees
 

Scalability Issues

Sentiment score
7.4
Microsoft Defender for Endpoint is scalable and integrates well with Microsoft’s ecosystem, despite needing improvements for handling massive data.
Sentiment score
8.0
Trend Micro Smart Protection scales effectively for businesses of all sizes with positive feedback on performance and flexibility.
We managed to scale it out in a short amount of time, with two months of planning and three months of implementation on 10,000 computers.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint is scalable enough to handle various devices across environments, whether they are laptops, Android devices, or operating in hybrid environments.
Snr. Infrastructure Architect (Data Centre) at LogicEra
Compatibility is its main feature.
IT CONSULTANT at a tech company with 10,001+ employees
 

Stability Issues

Sentiment score
7.9
Microsoft Defender for Endpoint is praised for its reliability and stability, with minor concerns about resource intensity and performance.
Sentiment score
7.7
Trend Micro Smart Protection is stable, reliable, and well-rated, though improved compatibility with major vendors could enhance user experience.
I haven't seen any outages with Microsoft.
IT Security Engineer at a financial services firm with 1,001-5,000 employees
I rate Defender 10 out of 10 for stability.
Team manager of it department at a financial services firm with 501-1,000 employees
Defender for Endpoint is extremely stable.
Systems engineers at Delta Dental of Colorado
 

Room For Improvement

Microsoft Defender for Endpoint faces interface complexity, slow detection, high CPU usage, integration issues, and seeks improvements in multiple areas.
Trend Micro Smart Protection needs enhancements in management tools, AI, compatibility, support, pricing, integration, and threat detection features.
Repeated interactions are necessary due to Level One's lack of tools and knowledge, hindering efficient problem-solving and negatively impacting our experience with Microsoft support.
Office 365 Subject Expert at a government with 10,001+ employees
In contrast, competing products offer reduced pricing for long-term commitments, which makes it difficult for us in that environment.
Solution Consultant at BIM Group of Companies
We use Microsoft partners to help govern the platform, and as part of an alliance, we want to gather data from each tenant and combine them for a complete view.
Team manager of it department at a financial services firm with 501-1,000 employees
We've experienced compatibility issues with Windows endpoint protection.
Security Architect at Kyndryl
 

Setup Cost

Microsoft Defender for Endpoint offers flexible pricing, making it competitive and cost-effective compared to standalone security products.
Trend Micro Smart Protection pricing varies widely, seen as competitive yet sometimes more expensive, with extensive licensing terms.
That has been the trend we have seen with Microsoft lately—it is just getting more and more expensive.
Assistant Director, Hybrid Infrastructure & Operations at a insurance company with 501-1,000 employees
Given our extensive Microsoft licensing, transitioning to Defender for Endpoint did not affect licensing costs.
Team manager of it department at a financial services firm with 501-1,000 employees
It costs $15 per VM for the P2 plan, which is seen as affordable for customers.
Snr. Infrastructure Architect (Data Centre) at LogicEra
However, their pricing is comparable to CrowdStrike.
Security Architect at Kyndryl
 

Valuable Features

Microsoft Defender for Endpoint excels with seamless integration, advanced threat intelligence, AI-driven protection, and continuous cloud-based security management.
Trend Micro Smart Protection delivers comprehensive security with robust features, low resource usage, scalability, and seamless IT system integration.
Defender for Endpoint's coverage across different platforms in our environment is pretty good. We have devices running Linux, Mac OS, Windows, iOS, and Android. It covers all of them.
Team manager of it department at a financial services firm with 501-1,000 employees
Microsoft Defender for Endpoint provides a unified management interface allowing customers to manage their on-premises and hybrid infrastructures from a single pane.
Snr. Infrastructure Architect (Data Centre) at LogicEra
One of the best features of Microsoft Defender for Endpoint is its database for identifying zero-day attacks or malware attacks.
Consultant at ACT4SERVICES
The most effective features of Trend Micro Smart Protection are its antivirus and malware capabilities.
Security Architect at Kyndryl
 

Categories and Ranking

Microsoft Defender for Endp...
Ranking in Endpoint Protection Platform (EPP)
2nd
Average Rating
8.2
Reviews Sentiment
7.0
Number of Reviews
210
Ranking in other categories
Advanced Threat Protection (ATP) (3rd), Anti-Malware Tools (1st), Endpoint Detection and Response (EDR) (2nd), Microsoft Security Suite (3rd)
Trend Micro Smart Protection
Ranking in Endpoint Protection Platform (EPP)
33rd
Average Rating
8.0
Reviews Sentiment
7.0
Number of Reviews
44
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of January 2026, in the Endpoint Protection Platform (EPP) category, the mindshare of Microsoft Defender for Endpoint is 8.2%, down from 11.5% compared to the previous year. The mindshare of Trend Micro Smart Protection is 0.9%, up from 0.5% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Endpoint Protection Platform (EPP) Market Share Distribution
ProductMarket Share (%)
Microsoft Defender for Endpoint8.2%
Trend Micro Smart Protection0.9%
Other90.9%
Endpoint Protection Platform (EPP)
 

Featured Reviews

Robert Arbuckle - PeerSpot reviewer
Security Analyst III at a healthcare company with 10,001+ employees
Automatically isolates threats and integrates with logging to reduce response time
Overall, I would evaluate the Microsoft support level that I receive at probably about a seven, but that depends on the day. It has been spotty. We have had issues where the urgency level of the Microsoft support is not as high as ours, especially during a data breach or potential data breach situation. We have had issues with some of the offshore support being lackluster. One specific thing that comes to mind is we were on a support call with our CISO on the call, and the Microsoft agent, who did not actually work for Microsoft, is one of the vendors that Microsoft uses for support, said, "Just to set expectations, my lunch break is in an hour and I am going to go away then." For us, it was already ten o'clock at night and we had been working on this for a couple of hours, trying to get a security engineer on with us. For him to tell us that he was going to go away and have lunch, it was, "Okay, but go find somebody else if you need to." It was just the lackluster approach, and it seemed like he did not really care. We seem to get a lot of this when we get non-Microsoft support. I can identify areas for improvement with Microsoft Defender for Endpoint, as it is kind of a convoluted mess to try to take care of false positives. Especially when they have been identified as false positives but they keep going off over and over again. It is great for my pocketbook because it generates a lot of on-call action, but I would really prefer more sleep at two o'clock in the morning than dealing with false positives. I would say that the unified portal for managing Microsoft Defender for Endpoint is suitable for both teams as they are all in there. It would be great if they would stop moving things around and renaming things, which makes sense. The new XDR portal is pretty nice. Being able to have it central again inside of the regular Security Center without having to open up two windows is helpful. Overall, I think it is pretty good. There is always going to be something that could be improved, such as alerting and the ability to modify alerts would be a little bit helpful to have. Being able to add more data into the alerts and turn off alerts that are not as useful would be beneficial. It is hard to say what the quantitative impact the security exposure management feature has had on our company's security, because a lot of it is kind of subjective. I think we are sitting at around a fifty percent score still, and a lot of it is just kind of unusual circumstances that we cannot really implement without breaking the organization.
DL
Security Architect at Kyndryl
Antivirus and malware capabilities effectively enhance threat prevention and integration
Our primary use case for Trend Micro Smart Protection is endpoint protection The most effective features of Trend Micro Smart Protection are its antivirus and malware capabilities.  Additionally, it integrates well with all our tools, including ServiceNow, for fault reporting. This integration…
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Use our free recommendation engine to learn which Endpoint Protection Platform (EPP) solutions are best for your needs.
879,425 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Computer Software Company
12%
Manufacturing Company
9%
Financial Services Firm
8%
Government
8%
Manufacturing Company
13%
Performing Arts
11%
Computer Software Company
9%
Healthcare Company
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business80
Midsize Enterprise40
Large Enterprise92
By reviewers
Company SizeCount
Small Business16
Midsize Enterprise14
Large Enterprise16
 

Questions from the Community

How is Cortex XDR compared with Microsoft Defender?
Microsoft Defender for Endpoint is a cloud-delivered endpoint security solution. The tool reduces the attack surface, applies behavioral-based endpoint protection and response, and includes risk-ba...
Which offers better endpoint security - Symantec or Microsoft Defender?
We use Symantec because we do not use MS Enterprise products, but in my opinion, Microsoft Defender is a superior solution. Microsoft Defender for Endpoint is a cloud-delivered endpoint security s...
How does Microsoft Defender for Endpoint compare with Crowdstrike Falcon?
The CrowdStrike solution delivers a lot of information about incidents. It has a very light sensor that will never push your machine hardware to "test", you don't have the usual "scan now" feature ...
What do you like most about Trend Micro Smart Protection?
The tool offers centralized security management. The tool's deployment is flexible.
What is your experience regarding pricing and costs for Trend Micro Smart Protection?
I find that Trend Micro Smart Protection is affordable; I don't think it can be quite expensive.
What needs improvement with Trend Micro Smart Protection?
Technical support needs to be improved. We had a customer move from Trend Micro because they didn't the support. Both response time and ownership are the problems with support. Trend Micro Smart Pr...
 

Also Known As

Microsoft Defender ATP, Microsoft Defender Advanced Threat Protection, MS Defender for Endpoint, Microsoft Defender Antivirus
Trend Micro Smart Protection Complete
 

Interactive Demo

Demo not available
 

Overview

 

Sample Customers

Petrofrac, Metro CSG, Christus Health
Atma Jaya Catholic University of Indonesia, Blekinge County Council, Bulgarian American Credit Bank, Cancer Research UK, Delacour, Evalueserve, Gulftainer, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Mazda Motor Logistics Europe, MEDHOST, Nikigolf, Ochsner Health System, SIAX Computing Solutions, Tegen
Find out what your peers are saying about Microsoft Defender for Endpoint vs. Trend Micro Smart Protection and other solutions. Updated: December 2025.
879,425 professionals have used our research since 2012.