No more typing reviews! Try our Samantha, our new voice AI agent.

Cisco Secure Email vs Microsoft Defender for Office 365 comparison

Sponsored
 

Comparison Buyer's Guide

Executive SummaryUpdated on Feb 8, 2026

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Cloudflare One
Sponsored
Ranking in Email Security
20th
Average Rating
8.6
Reviews Sentiment
6.5
Number of Reviews
23
Ranking in other categories
Secure Web Gateways (SWG) (13th), Data Loss Prevention (DLP) (20th), Cloud Access Security Brokers (CASB) (12th), Distributed Denial-of-Service (DDoS) Protection (7th), Software Defined WAN (SD-WAN) Solutions (12th), Access Management (11th), Bot Management (3rd), ZTNA as a Service (9th), ZTNA (4th), Secure Access Service Edge (SASE) (10th), Remote Browser Isolation (RBI) (3rd)
Cisco Secure Email
Ranking in Email Security
5th
Average Rating
8.4
Reviews Sentiment
6.9
Number of Reviews
63
Ranking in other categories
Cisco Security Portfolio (6th)
Microsoft Defender for Offi...
Ranking in Email Security
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
62
Ranking in other categories
Email Archiving (1st), Advanced Threat Protection (ATP) (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (1st)
 

Mindshare comparison

As of May 2026, in the Email Security category, the mindshare of Cloudflare One is 1.7%, up from 1.6% compared to the previous year. The mindshare of Cisco Secure Email is 4.7%, down from 6.6% compared to the previous year. The mindshare of Microsoft Defender for Office 365 is 6.9%, down from 12.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Email Security Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.9%
Cisco Secure Email4.7%
Cloudflare One1.7%
Other86.7%
Email Security
 

Featured Reviews

CV
Network Architect at IP Dimension
Cloud security has improved remote access and has reduced costs for smaller client sites
I have used Cloudflare One's Identity-Aware Proxy, and it is quite straightforward from what I have seen so far. The app registration on the Azure side integrates fully into Cloudflare, and I am very satisfied with that part because it is easy to set up. The integration of Cloudflare One's Secure Web Gateway and Zero Trust Network Access works without any issues. That part is pretty automatic, and if you complete the rest of the setup, it comes together by itself with no issues from my side. What makes it nice is that we can actually start replacing on-site firewalls at this stage for the smaller clients because it does not matter if they go to a coffee shop or work from home; they are still secured by the same connection. The hops get shorter and you get better latency. We have done testing to see if it is better. One thing that we did notice with our proof of concept with our current client is that they have people connecting from the UK. When they used their previous VPN solution, uploading CAD drawings and other files to the server took a long time. They mentioned that it is much quicker on Cloudflare One's solution. I definitely believe that is part of the improved performance, and I am satisfied with that as well. What is nice about Cloudflare One is that it makes the setup easier and also easier to train technicians to maintain it. Compared to legacy systems, we do not need to get fancy firewalls in place that are costly. That is definitely also a cost-saver with Cloudflare One.
KS
Technical Associate Network Security at Valuepoint Systems
Email security has protected financial data and provides clear tracking for every branch message
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it was a database error or something, but we feel some slowness in configuring DLP and other content filters compared to other consoles. It may have been due to on-premises, but it was much noisy at some times while configuring DLP. When we tried to configure a DLP policy, the console became much slower. In that case, we cannot see what had happened in the mail which was blocked at that time. It may take nearly an hour to get back to normal while configuring policies. That is the major issue in the product.
Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The solution has different options that can be used to differentiate DDoS attacks."
"We mostly use Cloudflare WAF, and gets basic Cloudflaire DDoS, caching as extra bonus . We like the factor these features are all integrated into 1 console, simple to manage."
"This solution is easy to understand and easy to configure."
"Clover is the best product globally."
"Cloudflare DDoS is better than its competitors for its security, deployment, and scalability."
"Enables me to work from two locations."
"Cloudflare DDoS mitigates DDoS attacks."
"Cloudflare Access is a stable solution."
"We chose Cisco Iron Port as it delivers strong email security protection and our company needed it to protect the company's email systems from spam, email viruses, .exe files, unwanted email from unwanted sender etc."
"It provided a platform to sell a service to customers."
"Overall, the ease of migration to Cisco's cloud email security from the on-prem solution was a positive experience."
"I can customize the configuration and policies."
"Anti-Spam and Advanced Malware Protection are the most valuable features; they provide protection from most email threats and we also have the option to block Zero-day attacks."
"This product is the complete solution and the real deal."
"It's a bit easy to handle Cisco Secure Email; it's not that difficult. For the logs, which are in PDF format, it's not hard to read them. We don't need Wireshark much to analyze the logs."
"It has an intuitive, clear graphical interface where you can deploy your policies and understand the overall flow. There are a lot of things that you cannot handle on the graphic interface, like message filters. For this, you need to go to a lower level where you have more power, like command line interface. So, this solution has the best of both worlds. There are not a lot of bells and whistles. It is more practical with access to most features that you can configure."
"The insights provided with Microsoft Defender for Office 365 are helpful because it comes with the E5 license, and by default, we can use a lot of capabilities."
"The insights provided with Microsoft Defender for Office 365 are helpful because it comes with the E5 license, and by default, we can use a lot of capabilities."
"One of the best features of the tool is its capability to aggregate insights from different workloads, basically from the Office 365 and endpoints part."
"My experience deploying Microsoft Defender for Office 365 was seamless."
"The most valuable feature of Microsoft Defender for Office 365 is the ease of use."
"Does a thorough job of examining email and URLs for malicious content."
"Microsoft Defender for Office 365 is a stable solution."
"Our customers are satisfied with Defender for 365 because Microsoft products are easy to use and customize to meet the client's needs. Everything is in one place, so we can adjust policies as needed for phishing, DLP, ATP, or any other security features that our clients want to apply."
 

Cons

"They don't have a person to provide support for customers using the solution under their free plan."
"The initial onboarding was causing us some confusion."
"The software has automated alerts, but the automated alerts are not available in the mobile app."
"The onboarding process can be improved a little bit."
"The initial onboarding was causing us some confusion."
"Operating and tuning the product is difficult."
"Cloudflare One is not very powerful, but for what we require, it is basic and sufficient."
"The free plan has limitations. For example, I can only set up three rules, and the application firewall is unavailable."
"The scalability must be improved."
"Cisco Email Secure's pricing needs to be less. We have vendors who provide cheaper solutions with the same features."
"Typically, in a phishing email, they try to use a name everybody's going to recognize, like the CEO's name or the CFO's name... With this appliance, the way it's designed at the moment, for us to really stop that with any level of confidence, we have to build a dictionary of all the names of the people we want it to check, and all the ways they could be spelled. My name would be in there as Phillip Collins, Phillip D. Collins, Phillip Dean Collins, Phil Collins, Phil D. Collins. There could be eight or 10 variations of my name that we'd have to put in the dictionary. There's no artificial intelligence to say "Phil Collins" could be all these other things, and to stop phishing from coming through in that way."
"While Cisco offers excellent solutions and innovations, the pricing may not be suitable for everyone. The cost of the software is relatively high. In the current market, there are numerous competitive alternatives that focus on security, enterprise networks, and various other aspects. Cisco, being a comprehensive provider, extends its expertise across data, servers, storage, and security, making them a preferred choice for many enterprises. However, when it comes specifically to security solutions, there are other vendors that specialize solely in this domain, offering competitive options."
"They could improve the filters. In my time at the company, there were several times we had to contact support to update the filters."
"Licensing is quite complicated for a number of customers, including ourselves."
"The interface is dated. It has looked pretty much the same for 15 years or so."
"I would like to see sandboxing for email, where suspicious emails received by the system are analyzed through online services."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"There's room for improvement regarding the time frame for retrieving emails."
"There is a different console for different things; I just want one consolidated console."
"There needs to be an improvement in having the product work across multiple operating systems and have better support for non-Microsoft file types."
"Microsoft security solutions work as expected. They are constantly updating the solutions to make them better. At the same time, the changes can impact a customer's environment, and we need to adjust settings. Sometimes we aren't aware of the changes, and nothing is pushed from the backend automatically."
"The custom alerts have to improve a lot."
"Microsoft Defender for Office 365 should improve the troubleshooting tools. It's unclear whether the device is blocked at the firewall level or at the device itself. The granularity needed for troubleshooting is currently lacking. From my perspective, Microsoft should address this issue to benefit many users who likely share the same sentiment."
"Sometimes I have to recategorize things when it takes the wrong step and I do not want it to classify something as suspicious."
 

Pricing and Cost Advice

"Cloudflare Zero Trust Platform's pricing is good."
"The pricing of the solution is cheap. The licensing cost is also very low. I rate the cost and pricing a three out of ten."
"The pricing is somewhere in the middle. I would rate the pricing a seven out of ten."
"My company has to make yearly payments towards the licensing costs attached to the solution. There are no hidden charges apart from the licensing costs of the solution."
"The solution's pricing lacks transparency."
"The price tag is no longer $200,000, but rather $300,000 to $400,000. It's twice."
"The solution is not that expensive."
"The prices are slightly expensive."
"It is not that costly. We pay for the solution through a contractor and pay an annual fee."
"The product's price falls on the higher side when compared to the other products on the market."
"It is expensive. I would rate it 2 out of 10, where 1 is the most expensive and 10 is the cheapest."
"Pricing depends on your environment and which model you want to buy."
"As per market availability, this solution is more expensive than other vendors."
"Compared to Cisco's on-prem service, the cost is the same, but you don't have to pay for the hardware and you don't have to maintain the system, as far as upgrades and hardware failures are concerned. It is cheaper to operate on their cloud service than it is to operate with their on-prem service."
"At times, we feel the pricing is a bit too high, but then, there is also room for discounts. We enjoy a lot of discounts, and that is why we are still with them. There are no costs in addition to the standard licensing fees."
"The price is significantly high."
"I know that the product is incredibly expensive."
"The product is very expensive."
"The product is expensive."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"For large enterprise organizations, they can definitely afford it, but for small and medium organizations, they might struggle to cover the expenses."
"From the pricing point of view, like any other product in the market, there is scope for negotiation."
"Microsoft Defender for Office 365 comes with Microsoft Windows. It is free with the operating system."
report
Use our free recommendation engine to learn which Email Security solutions are best for your needs.
892,487 professionals have used our research since 2012.
 

Top Industries

By visitors reading reviews
Construction Company
21%
Comms Service Provider
10%
Financial Services Firm
8%
Manufacturing Company
6%
Financial Services Firm
11%
Computer Software Company
9%
Manufacturing Company
9%
Government
6%
Computer Software Company
12%
Financial Services Firm
8%
Manufacturing Company
8%
Comms Service Provider
7%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business10
Midsize Enterprise2
Large Enterprise11
By reviewers
Company SizeCount
Small Business22
Midsize Enterprise18
Large Enterprise26
By reviewers
Company SizeCount
Small Business25
Midsize Enterprise11
Large Enterprise31
 

Questions from the Community

What needs improvement with Cloudflare Access?
Cloudflare Access has strong integration with Microsoft, among other platforms. However, when it comes to Kaspersky, ...
What is your primary use case for Cloudflare Access?
Cloudflare Access provides secure access to internal applications for employees, external members of the organization...
What advice do you have for others considering Cloudflare Access?
Cloudflare Access is one of the best integrations available. While about two hundred vendors offer similar services, ...
What do you like most about Cisco Secure Email?
Cisco Secure Email is a budget-friendly solution.
What is your experience regarding pricing and costs for Cisco Secure Email?
The pricing structure is good as it is user-based or email client-based, which is positive for clients.
What needs improvement with Cisco Secure Email?
The areas of Cisco Secure Email that could be improved or enhanced are the slowness in the console. I don't think it ...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking ...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
 

Also Known As

Cloudflare Area 1 Email Security, Cloudflare Bot Management, Cloudflare Gateway, Cloudflare Zero Trust Platform, Cloudflare DDoS, Cloudflare SASE & SSE Platform
Cisco Email Security, IronPort, Cisco Email Security, ESA, Email Security Appliances
MS Defender for Office 365
 

Overview

 

Sample Customers

23andMe
SUNY Old Westbury, CoxHealth, City of Fullerton, Indra
Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
Find out what your peers are saying about Cisco Secure Email vs. Microsoft Defender for Office 365 and other solutions. Updated: April 2026.
892,487 professionals have used our research since 2012.