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Microsoft Defender for Office 365 vs Trellix Advanced Threat Defense comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
1st
Average Rating
8.2
Reviews Sentiment
7.1
Number of Reviews
48
Ranking in other categories
Email Security (1st), Microsoft Security Suite (11th)
Trellix Advanced Threat Def...
Ranking in Advanced Threat Protection (ATP)
22nd
Average Rating
7.8
Reviews Sentiment
6.6
Number of Reviews
8
Ranking in other categories
No ranking in other categories
 

Mindshare comparison

As of April 2025, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 9.2%, down from 15.0% compared to the previous year. The mindshare of Trellix Advanced Threat Defense is 1.7%, up from 1.7% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP)
 

Featured Reviews

Tolu Omolaja - PeerSpot reviewer
Great URL scanning and attachment scanning, but I would like more proactive threat analysis
The two main features that prove most beneficial for us are URL scanning and attachment scanning. URL scanning involves an automatic scan of links and emails. When a user clicks on a link within an email, the system promptly checks the link's safety. If the link is deemed safe, access is granted automatically. However, if it is flagged as unsafe, we receive feedback and notification to caution us about the potentially harmful link. At this point, we are presented with the option to proceed or return. I have personally witnessed the system identify a few unsafe links, making this the primary advantage of using the solution. The second crucial aspect is the scanning of attachments. When an email containing an attachment arrives, we receive a notification of the new email, along with information that the attachment is being scanned for threats. This additional layer of security provides peace of mind for our organization. While Microsoft Defender for Office 365 offers numerous features, these two stand out as particularly impressive and valuable to us.
HS
Easy to set up and use with a nice interface
The scalability could be better. We'd like them to be better at dealing with script threats. In sandboxing, the time to respond is slower than we would like. We'd like them to be able to process faster. For example, Fortinet, they are doing 18,000 files per hour. For Wildfire, it is elastic. It can support as many files as you get. McAfee doesn't react like that. It does not support interfaces with HTTPS.

Quotes from Members

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

Pros

"The stability of Microsoft Defender for Office 365 is fantastic."
"I like its investigation capabilities, as that is what is most important to me. It is fairly simple with a user-friendly interface."
"Safe attachments, safe links, policies, and the ability to protect from zero-day threats are the most valuable features."
"The good part is that you don't have to configure it, which is very convenient."
"The benefit that stands out to me is the ability for multiple individuals to collaborate simultaneously within the same document. Additionally, there is the option to save the document directly in the integrated OneDrive or SharePoint."
"The deployment capability is a great feature."
"At the moment we are satisfied with this product. It's a stable, scalable, and resilient solution for us."
"Microsoft Defender has a feature to protect each and every attachment. Even if it's an encrypted attachment, it will check for any potential threats."
"Its greatest strength is the DXL client which can rapidly disseminate attack information to all clients via the McAfee Agent instead of going through the ePO server."
"Provides good exfiltration, and is an all-in-one product."
"It is very scalable."
"It stops in excess of twenty-five malware events per month, all of which could be critical to the business."
"I recommend this solution because of its ease of use."
"It is stable and reliable."
"The most valuable features are the administration console and its detection and response module."
 

Cons

"One area for improvement is integration. For example, when it comes to external SaaS platforms, we were not able to get a lot of information on integrations with such apps for security and authentication."
"Several simulation options are available within 365, and the phishing simulation could be better."
"Configuration at the mid-level could be improved for the support team."
"We noticed that from time to time, Microsoft's stability does have problems. Sometimes the service goes up and down. Sometimes they change without prior notice."
"In some situations, it has not been able to pick impersonated emails having no attachments. Technical support definitely has a scope for improvement."
"The pre-sales cost calculations could be more transparent."
"The XDR dashboard has room for improvement."
"We need to be able to whitelist data at the backend."
"This solution needs to be made "cloud ready"."
"We'd like them to be better at dealing with script threats."
"Lacks remote capabilities not dependent on the internet."
"There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client."
"Make the ATD system a part of the whole product and take the whole thing onto the cloud. While it is there already, it is not to the same level as the on-premise version."
"I would like to see future versions of the solution incorporate artificial intelligence technology."
"The initial setup was industry standard complex. It takes awhile and has a lot of planning involved. It could be simplified with product redesign."
 

Pricing and Cost Advice

"Compared to other brands, Microsoft Defender for Office 365's pricing is competitive."
"While Microsoft Defender for Office 365 necessitates pricier E3 or E5 subscriptions, the extensive functionality offered by these licenses across various Microsoft products justifies the investment."
"I was working in the government and it was too expensive for us to use our Microsoft products."
"For licensing, it's usually a yearly package for customers who are subscribed to Office 365, but they can also pay on a monthly basis."
"The product is expensive."
"Microsoft Defender for Office 365 is an add-on to the Office license. Many customers are purchasing this solution."
"The license is expensive because the cost is based on the number of users."
"Defender for 365 comes in various plans and licenses, along with other Microsoft security solutions. Purchasing this kind of package or security bundle gives good value for money, and that's what I recommend."
"The product is expensive, but it is better than the rest of them in the industry."
"Our licensing fees for this solution are approximately one million dollars per year."
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Top Industries

By visitors reading reviews
Computer Software Company
16%
Financial Services Firm
9%
Manufacturing Company
8%
Government
6%
Financial Services Firm
18%
Government
15%
Manufacturing Company
14%
Computer Software Company
11%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
 

Questions from the Community

What do you like most about Microsoft Defender for Office 365?
Threat Explorer is an invaluable tool for me, and it plays a crucial role in helping me discern the origins of various email campaigns, pinpointing where they emanate from, and identifying the indi...
What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
Money-wise, it is a part of the Office 365 ( /products/office-365-reviews ) suite, making it slightly more expensive compared to Trend Micro. Although Defender is free, you have to pay separately f...
What needs improvement with Microsoft Defender for Office 365?
The main area for improvement is simplifying the implementation and rollout process. There are many conditions to be met, making it challenging to ensure every system is protected. Troubleshooting ...
What do you like most about McAfee Advanced Threat Defense?
I recommend this solution because of its ease of use.
What needs improvement with McAfee Advanced Threat Defense?
There could be a tool that automatically updates all-new Microsoft IPs, which are available for free to connect to the client.
What is your primary use case for McAfee Advanced Threat Defense?
We use the solution for client management and security. We used the whole suite for client Firewall, antivirus, and everything provided by Trellix.
 

Also Known As

MS Defender for Office 365
McAfee Advanced Threat Defense
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
The Radicati Group, Florida International University, MGM Resorts International, County Durham andDarlington NHS Foundation Trust
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Advanced Threat Defense and other solutions. Updated: March 2025.
847,959 professionals have used our research since 2012.