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Microsoft Defender for Office 365 vs Trellix Network Detection and Response comparison

 

Comparison Buyer's Guide

Executive SummaryUpdated on Dec 1, 2024

Review summaries and opinions

We asked business professionals to review the solutions they use. Here are some excerpts of what they said:
 

ROI

Sentiment score
7.1
Microsoft Defender for Office 365 boosts efficiency, cuts phishing, integrates security, reduces tool costs, and mitigates risk.
Sentiment score
7.8
Trellix NDR boosts productivity and ROI, reduces threat response time, and is valued for preventing attacks and breaches.
It has also decreased our time to detection and response by about 15 to 20 percent.
Technology support manager at Alfred State College
Overall, cost of owning and operating our system goes down.
Designation Chief Consultant at Avtow
It's hard to quantify the return on investment we've seen from Microsoft Defender for Office 365.
Chief Architect at a tech vendor with 1,001-5,000 employees
The time was reduced because of the automated detections.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
 

Customer Service

Sentiment score
5.7
Microsoft Defender for Office 365 support is reliable but varies with subscription level and complexity of issues.
Sentiment score
6.6
Trellix Network Detection and Response support is mostly effective, with some users noting communication delays and areas for improvement.
Over the past two years, there have been no critical problems.
Solution Consultant at BIM Group of Companies
we opened tickets, and they typically resolve them quickly.
Chief Architect at a tech vendor with 1,001-5,000 employees
With a subscription for Microsoft Defender for Office 365, it is an eight. Without it, it is a six.
Manager at a tech services company with 10,001+ employees
Technical support needs improvement as sometimes engineers are not available promptly, especially during high-severity incidents.
Information Security Engineer at Nhq Distribution Ltd
They were constantly relaying our message to the engineering team and the engineering team was looping that back to them and then to us.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
The customer support for Trellix Network Detection and Response is great.
Agente De Servicios Técnicos at a computer software company with 11-50 employees
 

Scalability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 efficiently scales with cloud-native design, ensuring reliable performance and seamless integration for diverse organizations.
Sentiment score
7.1
Trellix Network Detection and Response effectively scales in cloud environments, smoothly handling diverse user bases and existing configurations.
We have never faced scalability problems, and Microsoft manages it effectively.
Solution Consultant at BIM Group of Companies
Microsoft Defender for Office 365 scales transparently for us, as we grew from 1,000 users to 3,000 users, and we didn't notice much difference.
Chief Architect at a tech vendor with 1,001-5,000 employees
Microsoft Defender for Office 365 scales with the growing needs of my company well.
Senior Client Director and Advisory Service Leader at Crossfuze
The connectors were always out of sync and we have had multiple noise floods from these connectors which were not configured well.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
 

Stability Issues

Sentiment score
7.8
Microsoft Defender for Office 365 offers consistently reliable performance with minimal downtime, high user ratings, and manageable minor issues.
Sentiment score
7.8
Trellix Network Detection is praised for stability and reliability, though some face downtime and memory or CPU issues.
I would rate the stability of Microsoft Defender for Office 365 as 10 over 10 because it's highly available, it works, and it does the job it is meant to do.
Cloud Solutions Architect at a tech services company with 201-500 employees
I have not experienced any downtime, crashes, or performance issues because of Defender.
Technology Associate at a financial services firm with 51-200 employees
The solution is stable, as we have been using it for the past two years.
Solution Consultant at BIM Group of Companies
Trellix Network Detection and Response is somewhat stable but there is a bit of downtime sometimes during the off-hours.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
 

Room For Improvement

Microsoft Defender for Office 365 needs improvements in usability, false positive reduction, phishing detection, scalability, and reporting capabilities.
Trellix Network Detection and Response needs enhancements in customization, integration, support, threat intelligence, and AI capabilities to reduce false positives.
The main area for improvement is simplifying the implementation and rollout process.
Infrastructure and Security Lead at Vedanta
Microsoft could improve by offering recommendations for domain spoofing attacks, especially scenarios where DNS records like SPF, DKIM, and DMARC are not properly published.
Solution Consultant at BIM Group of Companies
There is a different console for different things; I just want one consolidated console.
Senior Director, Security Architecture & Engineering at a leisure / travel company with 10,001+ employees
There should be improvements in AI intelligence, faster decision-making, and a more responsive technical support team.
Information Security Engineer at Nhq Distribution Ltd
When I need urgent support from Trellix, there is a response after four hours or three hours.
IT Manager at Gigabit Technologies Pvt Ltd
Trellix Network Detection and Response needs to deepen the cloud-native support with parity between on-premises and cloud deployments.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
 

Setup Cost

Microsoft Defender for Office 365 is cost-effective with E5, costly standalone, requiring careful planning for subscription-based licensing.
Trellix Network Detection and Response is costly, yet valued for quality threat detection, appealing to larger enterprises over smaller clients.
We've likely saved 30% of costs.
Designation Chief Consultant at Avtow
Money-wise, it is a part of the Office 365 suite, making it slightly more expensive compared to Trend Micro.
Infrastructure and Security Lead at Vedanta
Microsoft is quite affordable with a lot of features available for any size organization.
Solution Consultant at BIM Group of Companies
The price for Trellix Network Detection and Response is reasonable.
IT Manager at Gigabit Technologies Pvt Ltd
I am sure the ROI was definitely fine for this because we were using this tool for three years.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
 

Valuable Features

Microsoft Defender for Office 365 enhances security with AI-driven phishing detection and robust protection across Microsoft 365 services.
Trellix NDR excels in zero-day detection, integrates with security platforms, reduces alert fatigue, and offers user-friendly threat analysis.
It ranks the threats and allows us to prioritize those hitting us the hardest, such as email threats.
Technology support manager at Alfred State College
It provides end-to-end visibility on email threats such as phishing, extending beyond Exchange Online Protection.
Solution Consultant at BIM Group of Companies
The value of the DLP feature is significant to us because we have internal data, sometimes sensitive, and the users may not always be aware of security and privacy, which might lead them to send out information mistakenly to external parties.
Chief Architect at a tech vendor with 1,001-5,000 employees
Per day we used to have 70 to 80 alerts and those could be reduced up to 40 to 30 a day. This is almost a 40 to 50% decrease.
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
Trellix NDR provides an essential defense by automatically responding to network incidents that firewalls may not catch.
Information Security Engineer at Nhq Distribution Ltd
What makes Trellix Network Detection and Response stand out for me compared to other tools is the way you can detect threats. It is very easy and comfortable to use, and the detection shows clearly on the screen, which is very easy to understand.
Agente De Servicios Técnicos at a computer software company with 11-50 employees
 

Categories and Ranking

Microsoft Defender for Offi...
Ranking in Advanced Threat Protection (ATP)
2nd
Average Rating
8.4
Reviews Sentiment
6.8
Number of Reviews
61
Ranking in other categories
Email Archiving (1st), Email Security (2nd), Microsoft Security Suite (8th), Secure Email Gateway (SEG) (1st)
Trellix Network Detection a...
Ranking in Advanced Threat Protection (ATP)
17th
Average Rating
8.4
Reviews Sentiment
7.1
Number of Reviews
42
Ranking in other categories
Network Detection and Response (NDR) (13th)
 

Mindshare comparison

As of May 2026, in the Advanced Threat Protection (ATP) category, the mindshare of Microsoft Defender for Office 365 is 6.7%, down from 14.9% compared to the previous year. The mindshare of Trellix Network Detection and Response is 4.1%, up from 3.9% compared to the previous year. It is calculated based on PeerSpot user engagement data.
Advanced Threat Protection (ATP) Mindshare Distribution
ProductMindshare (%)
Microsoft Defender for Office 3656.7%
Trellix Network Detection and Response4.1%
Other89.2%
Advanced Threat Protection (ATP)
 

Featured Reviews

Emeka Ndulu - PeerSpot reviewer
Cloud Solutions Architect at a tech services company with 201-500 employees
Improves threat visibility and response while reducing manual tasks and training users against phishing
I appreciate the attack simulation feature whereby I get to train users and educate them on how to identify phishing emails and spam emails, as well as the anti-spam protection. It gives me visibility into my threat environment and threat landscape to ensure that I am one step ahead of any likelihood of threats within my environment. I get to detect it and respond, so the threat intelligence is very effective. Microsoft security solutions save my time. It saves money because once I protect my environment, I don't lose money. It has decreased my detection time and my time to respond.
reviewer2840397 - PeerSpot reviewer
Associate Cybersecurity Analyst at a tech vendor with 10,001+ employees
Threat detection has improved for zero‑day attacks but alert noise and support still need work
There are many ways Trellix Network Detection and Response can be improved. Trellix Network Detection and Response needs to reduce the alert noise because even after a lot of filtering, there is still a lot of noise which needs to be tuned by the industry vertical. Trellix Network Detection and Response needs to deepen the cloud-native support with parity between on-premises and cloud deployments. Trellix Network Detection and Response needs to improve threat intelligence depth as Trellix Network Detection and Response is not known to have the best signatures or the AI-supported intelligence that competitors may have. Trellix Network Detection and Response also needs revamped documentation because we had a lot of issues trying to find the syntaxes for all the rule-making. We had to search a lot and Trellix Network Detection and Response does not really help with their documentation, as it only covers basic information. The customer service is not that good. Trellix Network Detection and Response needs accelerated customer support to reach out to the top-level heads. Most of the time we are just stuck at the ground level talking to their customer support team, and they are not able to help us because we usually need to connect with the engineering team to help us out with the specifics.
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Top Industries

By visitors reading reviews
Computer Software Company
12%
Financial Services Firm
9%
Manufacturing Company
8%
Comms Service Provider
7%
Financial Services Firm
14%
Comms Service Provider
12%
Manufacturing Company
11%
Government
8%
 

Company Size

By reviewers
Large Enterprise
Midsize Enterprise
Small Business
By reviewers
Company SizeCount
Small Business24
Midsize Enterprise12
Large Enterprise32
By reviewers
Company SizeCount
Small Business21
Midsize Enterprise8
Large Enterprise20
 

Questions from the Community

What is your experience regarding pricing and costs for Microsoft Defender for Office 365?
My experience with pricing, setup, and licensing is that it's actually quite reasonable even on the licensing side as a standalone product. It's very competitive compared to what competitors are ch...
What needs improvement with Microsoft Defender for Office 365?
I think Microsoft Defender for Office 365 can be improved by creating more educational pieces about not just looking for malware. We are seeing a lot more malware-less emails that Defender for Offi...
What is your primary use case for Microsoft Defender for Office 365?
My main use cases for Microsoft Defender for Office 365 include email hygiene.
What is your experience regarding pricing and costs for FireEye Network Security?
My experience with pricing, setup cost, and licensing for Trellix Network Detection and Response is very great.
What needs improvement with FireEye Network Security?
I would like to see in Trellix Network Detection and Response more explanation about some details of the threat, and I wish it had more actions that you can take to contain the host or move it some...
What is your primary use case for FireEye Network Security?
My main use case for Trellix Network Detection and Response is providing support for our customers, and one of our customers has Trellix, so we had to provide monitoring or specific XDR tools for t...
 

Also Known As

MS Defender for Office 365
FireEye Network Security, FireEye
 

Overview

 

Sample Customers

Microsoft Defender for Office 365 is trusted by companies such as Ithaca College.
FFRDC, Finansbank, Japan Advanced Institute of Science and Technology, Investis, Kelsey-Seybold Clinic, Bank of Thailand, City of Miramar, Citizens National Bank, D-Wave Systems
Find out what your peers are saying about Microsoft Defender for Office 365 vs. Trellix Network Detection and Response and other solutions. Updated: April 2026.
894,998 professionals have used our research since 2012.